8QLL

Crystal structure of rat glutathione transferase Omega 1 bound to glutathione

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0005604	cellular_component	basement membrane
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006749	biological_process	glutathione metabolic process
A	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
A	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
A	0014810	biological_process	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
A	0016491	molecular_function	oxidoreductase activity
A	0016740	molecular_function	transferase activity
A	0019852	biological_process	L-ascorbic acid metabolic process
A	0019853	biological_process	L-ascorbic acid biosynthetic process
A	0030424	cellular_component	axon
A	0031965	cellular_component	nuclear membrane
A	0042178	biological_process	xenobiotic catabolic process
A	0044297	cellular_component	cell body
A	0045174	molecular_function	glutathione dehydrogenase (ascorbate) activity
A	0050610	molecular_function	methylarsonate reductase activity
A	0051280	biological_process	negative regulation of release of sequestered calcium ion into cytosol
A	0051281	biological_process	positive regulation of release of sequestered calcium ion into cytosol
A	0071243	biological_process	cellular response to arsenic-containing substance
A	0098869	biological_process	cellular oxidant detoxification
B	0004364	molecular_function	glutathione transferase activity
B	0005604	cellular_component	basement membrane
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006749	biological_process	glutathione metabolic process
B	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
B	0014810	biological_process	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
B	0016491	molecular_function	oxidoreductase activity
B	0016740	molecular_function	transferase activity
B	0019852	biological_process	L-ascorbic acid metabolic process
B	0019853	biological_process	L-ascorbic acid biosynthetic process
B	0030424	cellular_component	axon
B	0031965	cellular_component	nuclear membrane
B	0042178	biological_process	xenobiotic catabolic process
B	0044297	cellular_component	cell body
B	0045174	molecular_function	glutathione dehydrogenase (ascorbate) activity
B	0050610	molecular_function	methylarsonate reductase activity
B	0051280	biological_process	negative regulation of release of sequestered calcium ion into cytosol
B	0051281	biological_process	positive regulation of release of sequestered calcium ion into cytosol
B	0071243	biological_process	cellular response to arsenic-containing substance
B	0098869	biological_process	cellular oxidant detoxification

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	158
Details	Domain: {"description":"GST N-terminal"}

Chain

Residue

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site_id	SWS_FT_FI2
Number of Residues	244
Details	Domain: {"description":"GST C-terminal"}

Chain

Residue

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"P78417","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P78417","evidenceCode":"ECO:0000250"}]}

Chain

Residue

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site_id	SWS_FT_FI5
Number of Residues	8
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P78417","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P78417","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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