8QKK
Cryo-EM structure of MmpL3 from Mycobacterium smegmatis reconstituted into peptidiscs
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 240 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE15-GLY35 | |
| A | MET631-VAL651 | |
| A | ILE679-VAL699 | |
| A | LEU704-VAL724 | |
| A | VAL197-ILE217 | |
| A | GLY218-VAL238 | |
| A | PHE241-ILE261 | |
| A | VAL291-PHE311 | |
| A | ALA318-LEU338 | |
| A | ILE402-LEU422 | |
| A | ALA568-LEU588 | |
| A | ALA592-VAL612 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 330 |
| Details | TOPO_DOM: Periplasmic => ECO:0000305|PubMed:30682372, ECO:0000305|PubMed:31113875 |
| Chain | Residue | Details |
| A | ASN36-LEU196 | |
| A | HIS239-PHE240 | |
| A | LEU312-TYR317 | |
| A | SER423-MET567 | |
| A | ASP613-PRO630 | |
| A | MET700-TYR703 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 118 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:30682372, ECO:0000305|PubMed:31113875 |
| Chain | Residue | Details |
| A | VAL262-VAL290 | |
| A | ALA339-PRO401 | |
| A | PRO589-LYS591 | |
| A | SER652-LEU678 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31113875, ECO:0007744|PDB:6OR2 |
| Chain | Residue | Details |
| A | GLN40 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:30682372, ECO:0007744|PDB:6AJG |
| Chain | Residue | Details |
| A | ASP645 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | SITE: Part of the proton-transportation channel => ECO:0000305|PubMed:30682372, ECO:0000305|PubMed:31113875 |
| Chain | Residue | Details |
| A | ASP256 | |
| A | TYR257 | |
| A | TYR646 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | SITE: Part of the proton transportation network => ECO:0000305|PubMed:31113875 |
| Chain | Residue | Details |
| A | LYS591 | |
| A | GLU647 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | SITE: Part of the proton-transportation channel => ECO:0000305|PubMed:30682372, ECO:0000305|PubMed:31113875, ECO:0000305|PubMed:32512002 |
| Chain | Residue | Details |
| A | ASP645 |
