8QJX
Human Adenovirus type 11 fiber knob in complex with two copies of its cell receptor, Desmoglein-2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007155 | biological_process | cell adhesion |
| A | 0019028 | cellular_component | viral capsid |
| A | 0019058 | biological_process | viral life cycle |
| A | 0019062 | biological_process | virion attachment to host cell |
| A | 0042025 | cellular_component | host cell nucleus |
| A | 0046718 | biological_process | symbiont entry into host cell |
| A | 0098671 | biological_process | adhesion receptor-mediated virion attachment to host cell |
| B | 0007155 | biological_process | cell adhesion |
| B | 0019028 | cellular_component | viral capsid |
| B | 0019058 | biological_process | viral life cycle |
| B | 0019062 | biological_process | virion attachment to host cell |
| B | 0042025 | cellular_component | host cell nucleus |
| B | 0046718 | biological_process | symbiont entry into host cell |
| B | 0098671 | biological_process | adhesion receptor-mediated virion attachment to host cell |
| C | 0007155 | biological_process | cell adhesion |
| C | 0019028 | cellular_component | viral capsid |
| C | 0019058 | biological_process | viral life cycle |
| C | 0019062 | biological_process | virion attachment to host cell |
| C | 0042025 | cellular_component | host cell nucleus |
| C | 0046718 | biological_process | symbiont entry into host cell |
| C | 0098671 | biological_process | adhesion receptor-mediated virion attachment to host cell |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0007155 | biological_process | cell adhesion |
| D | 0007156 | biological_process | homophilic cell adhesion via plasma membrane adhesion molecules |
| D | 0016020 | cellular_component | membrane |
| E | 0005509 | molecular_function | calcium ion binding |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0007155 | biological_process | cell adhesion |
| E | 0007156 | biological_process | homophilic cell adhesion via plasma membrane adhesion molecules |
| E | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00232 |
| Number of Residues | 11 |
| Details | CADHERIN_1 Cadherin domain signature. IkVlDiNDNeP |
| Chain | Residue | Details |
| D | ILE98-PRO108 | |
| D | ILE211-PRO221 | |
| D | ILE438-PRO448 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1118 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| D | ALA1-GLY560 | |
| E | ALA1-GLY560 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 48 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| D | LEU561-MET585 | |
| E | LEU561-MET585 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 966 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| D | CYS586-SER1069 | |
| E | CYS586-SER1069 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| D | SER631 | |
| E | SER631 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| D | SER651 | |
| D | SER757 | |
| D | SER761 | |
| D | SER766 | |
| E | SER651 | |
| E | SER757 | |
| E | SER761 | |
| E | SER766 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692 |
| Chain | Residue | Details |
| D | SER654 | |
| E | SER654 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| D | SER674 | |
| D | SER677 | |
| E | SER674 | |
| E | SER677 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| D | THR755 | |
| D | THR873 | |
| E | THR755 | |
| E | THR873 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231 |
| Chain | Residue | Details |
| D | SER1069 | |
| E | SER1069 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| D | ASN63 | |
| E | ASN63 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| D | ASN133 | |
| E | ASN133 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| D | ASN260 | |
| D | ASN465 | |
| E | ASN260 | |
| E | ASN465 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:19139490, ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| D | ASN413 | |
| E | ASN413 |
