8QHD

Hantaan virus polymerase in hexameric state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001172	biological_process	RNA-templated transcription
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0006351	biological_process	DNA-templated transcription
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0019079	biological_process	viral genome replication
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0039689	biological_process	negative stranded viral RNA replication
A	0039694	biological_process	viral RNA genome replication
A	0039696	biological_process	RNA-templated viral transcription
A	0044220	cellular_component	host cell perinuclear region of cytoplasm
A	0046872	molecular_function	metal ion binding
A	0075526	biological_process	cap snatching
B	0000166	molecular_function	nucleotide binding
B	0001172	biological_process	RNA-templated transcription
B	0003968	molecular_function	RNA-directed RNA polymerase activity
B	0004518	molecular_function	nuclease activity
B	0004519	molecular_function	endonuclease activity
B	0006351	biological_process	DNA-templated transcription
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0016787	molecular_function	hydrolase activity
B	0019079	biological_process	viral genome replication
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0039689	biological_process	negative stranded viral RNA replication
B	0039694	biological_process	viral RNA genome replication
B	0039696	biological_process	RNA-templated viral transcription
B	0044220	cellular_component	host cell perinuclear region of cytoplasm
B	0046872	molecular_function	metal ion binding
B	0075526	biological_process	cap snatching
C	0000166	molecular_function	nucleotide binding
C	0001172	biological_process	RNA-templated transcription
C	0003968	molecular_function	RNA-directed RNA polymerase activity
C	0004518	molecular_function	nuclease activity
C	0004519	molecular_function	endonuclease activity
C	0006351	biological_process	DNA-templated transcription
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0016787	molecular_function	hydrolase activity
C	0019079	biological_process	viral genome replication
C	0034062	molecular_function	5'-3' RNA polymerase activity
C	0039689	biological_process	negative stranded viral RNA replication
C	0039694	biological_process	viral RNA genome replication
C	0039696	biological_process	RNA-templated viral transcription
C	0044220	cellular_component	host cell perinuclear region of cytoplasm
C	0046872	molecular_function	metal ion binding
C	0075526	biological_process	cap snatching
D	0000166	molecular_function	nucleotide binding
D	0001172	biological_process	RNA-templated transcription
D	0003968	molecular_function	RNA-directed RNA polymerase activity
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0006351	biological_process	DNA-templated transcription
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0016787	molecular_function	hydrolase activity
D	0019079	biological_process	viral genome replication
D	0034062	molecular_function	5'-3' RNA polymerase activity
D	0039689	biological_process	negative stranded viral RNA replication
D	0039694	biological_process	viral RNA genome replication
D	0039696	biological_process	RNA-templated viral transcription
D	0044220	cellular_component	host cell perinuclear region of cytoplasm
D	0046872	molecular_function	metal ion binding
D	0075526	biological_process	cap snatching
E	0000166	molecular_function	nucleotide binding
E	0001172	biological_process	RNA-templated transcription
E	0003968	molecular_function	RNA-directed RNA polymerase activity
E	0004518	molecular_function	nuclease activity
E	0004519	molecular_function	endonuclease activity
E	0006351	biological_process	DNA-templated transcription
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0016787	molecular_function	hydrolase activity
E	0019079	biological_process	viral genome replication
E	0034062	molecular_function	5'-3' RNA polymerase activity
E	0039689	biological_process	negative stranded viral RNA replication
E	0039694	biological_process	viral RNA genome replication
E	0039696	biological_process	RNA-templated viral transcription
E	0044220	cellular_component	host cell perinuclear region of cytoplasm
E	0046872	molecular_function	metal ion binding
E	0075526	biological_process	cap snatching
F	0000166	molecular_function	nucleotide binding
F	0001172	biological_process	RNA-templated transcription
F	0003968	molecular_function	RNA-directed RNA polymerase activity
F	0004518	molecular_function	nuclease activity
F	0004519	molecular_function	endonuclease activity
F	0006351	biological_process	DNA-templated transcription
F	0016740	molecular_function	transferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0016787	molecular_function	hydrolase activity
F	0019079	biological_process	viral genome replication
F	0034062	molecular_function	5'-3' RNA polymerase activity
F	0039689	biological_process	negative stranded viral RNA replication
F	0039694	biological_process	viral RNA genome replication
F	0039696	biological_process	RNA-templated viral transcription
F	0044220	cellular_component	host cell perinuclear region of cytoplasm
F	0046872	molecular_function	metal ion binding
F	0075526	biological_process	cap snatching

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1116
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Active site: {"description":"For endonuclease activity","evidences":[{"source":"PubMed","id":"27304209","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	30
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27304209","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"I0DF35","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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