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8QHD

Hantaan virus polymerase in hexameric state

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0001172biological_processRNA-templated transcription
A0003968molecular_functionRNA-dependent RNA polymerase activity
A0004519molecular_functionendonuclease activity
A0006351biological_processDNA-templated transcription
A0019079biological_processviral genome replication
A0030430cellular_componenthost cell cytoplasm
A0034062molecular_function5'-3' RNA polymerase activity
A0039689biological_processnegative stranded viral RNA replication
A0039694biological_processviral RNA genome replication
A0039696biological_processRNA-templated viral transcription
A0044220cellular_componenthost cell perinuclear region of cytoplasm
A0046872molecular_functionmetal ion binding
A0075526biological_processcap snatching
B0000166molecular_functionnucleotide binding
B0001172biological_processRNA-templated transcription
B0003968molecular_functionRNA-dependent RNA polymerase activity
B0004519molecular_functionendonuclease activity
B0006351biological_processDNA-templated transcription
B0019079biological_processviral genome replication
B0030430cellular_componenthost cell cytoplasm
B0034062molecular_function5'-3' RNA polymerase activity
B0039689biological_processnegative stranded viral RNA replication
B0039694biological_processviral RNA genome replication
B0039696biological_processRNA-templated viral transcription
B0044220cellular_componenthost cell perinuclear region of cytoplasm
B0046872molecular_functionmetal ion binding
B0075526biological_processcap snatching
C0000166molecular_functionnucleotide binding
C0001172biological_processRNA-templated transcription
C0003968molecular_functionRNA-dependent RNA polymerase activity
C0004519molecular_functionendonuclease activity
C0006351biological_processDNA-templated transcription
C0019079biological_processviral genome replication
C0030430cellular_componenthost cell cytoplasm
C0034062molecular_function5'-3' RNA polymerase activity
C0039689biological_processnegative stranded viral RNA replication
C0039694biological_processviral RNA genome replication
C0039696biological_processRNA-templated viral transcription
C0044220cellular_componenthost cell perinuclear region of cytoplasm
C0046872molecular_functionmetal ion binding
C0075526biological_processcap snatching
D0000166molecular_functionnucleotide binding
D0001172biological_processRNA-templated transcription
D0003968molecular_functionRNA-dependent RNA polymerase activity
D0004519molecular_functionendonuclease activity
D0006351biological_processDNA-templated transcription
D0019079biological_processviral genome replication
D0030430cellular_componenthost cell cytoplasm
D0034062molecular_function5'-3' RNA polymerase activity
D0039689biological_processnegative stranded viral RNA replication
D0039694biological_processviral RNA genome replication
D0039696biological_processRNA-templated viral transcription
D0044220cellular_componenthost cell perinuclear region of cytoplasm
D0046872molecular_functionmetal ion binding
D0075526biological_processcap snatching
E0000166molecular_functionnucleotide binding
E0001172biological_processRNA-templated transcription
E0003968molecular_functionRNA-dependent RNA polymerase activity
E0004519molecular_functionendonuclease activity
E0006351biological_processDNA-templated transcription
E0019079biological_processviral genome replication
E0030430cellular_componenthost cell cytoplasm
E0034062molecular_function5'-3' RNA polymerase activity
E0039689biological_processnegative stranded viral RNA replication
E0039694biological_processviral RNA genome replication
E0039696biological_processRNA-templated viral transcription
E0044220cellular_componenthost cell perinuclear region of cytoplasm
E0046872molecular_functionmetal ion binding
E0075526biological_processcap snatching
F0000166molecular_functionnucleotide binding
F0001172biological_processRNA-templated transcription
F0003968molecular_functionRNA-dependent RNA polymerase activity
F0004519molecular_functionendonuclease activity
F0006351biological_processDNA-templated transcription
F0019079biological_processviral genome replication
F0030430cellular_componenthost cell cytoplasm
F0034062molecular_function5'-3' RNA polymerase activity
F0039689biological_processnegative stranded viral RNA replication
F0039694biological_processviral RNA genome replication
F0039696biological_processRNA-templated viral transcription
F0044220cellular_componenthost cell perinuclear region of cytoplasm
F0046872molecular_functionmetal ion binding
F0075526biological_processcap snatching
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsACT_SITE: For endonuclease activity => ECO:0000305|PubMed:27304209
ChainResidueDetails
DLYS124
BLYS124
CLYS124
FLYS124
ALYS124
ELYS124

site_idSWS_FT_FI2
Number of Residues30
DetailsBINDING: BINDING => ECO:0000269|PubMed:27304209
ChainResidueDetails
DHIS36
BVAL111
CHIS36
CGLU54
CASP97
CGLU110
CVAL111
FHIS36
FGLU54
FASP97
FGLU110
DGLU54
FVAL111
AHIS36
AGLU54
AASP97
AGLU110
AVAL111
EHIS36
EGLU54
EASP97
EGLU110
DASP97
EVAL111
DGLU110
DVAL111
BHIS36
BGLU54
BASP97
BGLU110

site_idSWS_FT_FI3
Number of Residues6
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:I0DF35
ChainResidueDetails
DASP1099
BASP1099
CASP1099
FASP1099
AASP1099
EASP1099

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PDB entries from 2024-07-24

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