8QGW
Crystal structure of oxidized respiratory Complex I subunits NuoEF from Aquifex aeolicus bound to oxidized 3-acetylpyridine adenine dinucleotide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003954 | molecular_function | NADH dehydrogenase activity |
| A | 0045271 | cellular_component | respiratory chain complex I |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048038 | molecular_function | quinone binding |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0048038 | molecular_function | quinone binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0003954 | molecular_function | NADH dehydrogenase activity |
| C | 0045271 | cellular_component | respiratory chain complex I |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0048038 | molecular_function | quinone binding |
| C | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0048038 | molecular_function | quinone binding |
| D | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGFGGTGTVIvLteeddive..........AALK |
| Chain | Residue | Details |
| B | LEU314-LYS337 |
| site_id | PS00644 |
| Number of Residues | 16 |
| Details | COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES |
| Chain | Residue | Details |
| B | GLY176-SER191 |
| site_id | PS00645 |
| Number of Residues | 12 |
| Details | COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ETCGqCtPCRvG |
| Chain | Residue | Details |
| B | GLU345-GLY356 |
| site_id | PS01099 |
| Number of Residues | 19 |
| Details | COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DgkFKivpvqCLGaCseAP |
| Chain | Residue | Details |
| A | ASP117-PRO135 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| B | GLY65 | |
| B | GLY176 | |
| D | GLY65 | |
| D | GLY176 | |
| C | CYS86 | |
| C | CYS91 | |
| C | CYS127 | |
| C | CYS131 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| B | CYS347 | |
| B | CYS350 | |
| B | CYS353 | |
| B | CYS393 | |
| D | CYS347 | |
| D | CYS350 | |
| D | CYS353 | |
| D | CYS393 |
