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8QAU

Outer kinetochore Ndc80-Dam1 alpha/beta-tubulin complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000775cellular_componentchromosome, centromeric region
A0000776cellular_componentkinetochore
A0000779cellular_componentcondensed chromosome, centromeric region
A0000940cellular_componentouter kinetochore
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005694cellular_componentchromosome
A0007059biological_processchromosome segregation
A0008017molecular_functionmicrotubule binding
A0031262cellular_componentNdc80 complex
A0034501biological_processprotein localization to kinetochore
A0042802molecular_functionidentical protein binding
A0051301biological_processcell division
A0051315biological_processattachment of mitotic spindle microtubules to kinetochore
A1990758biological_processmitotic sister chromatid biorientation
B0000775cellular_componentchromosome, centromeric region
B0000776cellular_componentkinetochore
B0000779cellular_componentcondensed chromosome, centromeric region
B0000940cellular_componentouter kinetochore
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005694cellular_componentchromosome
B0005816cellular_componentspindle pole body
B0005876cellular_componentspindle microtubule
B0007052biological_processmitotic spindle organization
B0007059biological_processchromosome segregation
B0008017molecular_functionmicrotubule binding
B0031262cellular_componentNdc80 complex
B0044877molecular_functionprotein-containing complex binding
B0045132biological_processmeiotic chromosome segregation
B0051301biological_processcell division
B0051315biological_processattachment of mitotic spindle microtubules to kinetochore
B0051383biological_processkinetochore organization
C0000226biological_processmicrotubule cytoskeleton organization
C0000278biological_processmitotic cell cycle
C0005200molecular_functionstructural constituent of cytoskeleton
C0005525molecular_functionGTP binding
C0005737cellular_componentcytoplasm
C0005856cellular_componentcytoskeleton
C0005874cellular_componentmicrotubule
C0007017biological_processmicrotubule-based process
C0016787molecular_functionhydrolase activity
C0031514cellular_componentmotile cilium
C0046872molecular_functionmetal ion binding
D0000226biological_processmicrotubule cytoskeleton organization
D0000278biological_processmitotic cell cycle
D0003924molecular_functionGTPase activity
D0005200molecular_functionstructural constituent of cytoskeleton
D0005515molecular_functionprotein binding
D0005525molecular_functionGTP binding
D0005737cellular_componentcytoplasm
D0005856cellular_componentcytoskeleton
D0005874cellular_componentmicrotubule
D0007017biological_processmicrotubule-based process
D0046872molecular_functionmetal ion binding
E0000775cellular_componentchromosome, centromeric region
E0000776cellular_componentkinetochore
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005694cellular_componentchromosome
E0005737cellular_componentcytoplasm
E0005819cellular_componentspindle
E0005856cellular_componentcytoskeleton
E0005874cellular_componentmicrotubule
E0007059biological_processchromosome segregation
E0008017molecular_functionmicrotubule binding
E0008608biological_processattachment of spindle microtubules to kinetochore
E0031116biological_processpositive regulation of microtubule polymerization
E0042729cellular_componentDASH complex
E0042802molecular_functionidentical protein binding
E0044732cellular_componentmitotic spindle pole body
E0051010molecular_functionmicrotubule plus-end binding
E0051301biological_processcell division
E0051987biological_processpositive regulation of attachment of spindle microtubules to kinetochore
E0071459biological_processprotein localization to chromosome, centromeric region
E0072686cellular_componentmitotic spindle
E0098653biological_processcentromere clustering
E1990537cellular_componentmitotic spindle polar microtubule
E1990758biological_processmitotic sister chromatid biorientation
E1990976biological_processprotein transport along microtubule to mitotic spindle pole body
Functional Information from PROSITE/UniProt
site_idPS00227
Number of Residues7
DetailsTUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG
ChainResidueDetails
CGLY142-GLY148
DGLY140-GLY146

site_idPS00228
Number of Residues4
DetailsTUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI
ChainResidueDetails
DMET1-ILE4

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378
ChainResidueDetails
ESER2
DSER138
DGLY142
DTHR143
DGLY144
DASN204
DASN226

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine; by IPL1 => ECO:0000269|PubMed:12408861
ChainResidueDetails
ESER20
ESER257
CSER140
CGLY144
CTHR145
CTHR179
CASN206
CASN228

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950
ChainResidueDetails
ESER31

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine; by IPL1 => ECO:0000269|PubMed:12408861, ECO:0007744|PubMed:19779198
ChainResidueDetails
ESER265
ESER292

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphoserine; by CDK1 => ECO:0000250|UniProtKB:Q13885
ChainResidueDetails
DSER172

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P07437
ChainResidueDetails
DTHR285
DTHR290

site_idSWS_FT_FI7
Number of Residues1
DetailsMOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:P07437
ChainResidueDetails
DARG318

site_idSWS_FT_FI8
Number of Residues1
DetailsMOD_RES: 5-glutamyl polyglutamate => ECO:0000250|UniProtKB:Q2T9S0
ChainResidueDetails
DGLU438

site_idSWS_FT_FI9
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P07437
ChainResidueDetails
DLYS58

site_idSWS_FT_FI10
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P07437
ChainResidueDetails
DLYS324

223790

PDB entries from 2024-08-14

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