8Q9T

CryoEM structure of a S. Cerevisiae Ski238 complex bound to RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000956	biological_process	nuclear-transcribed mRNA catabolic process
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0003729	molecular_function	mRNA binding
A	0004386	molecular_function	helicase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006401	biological_process	RNA catabolic process
A	0006402	biological_process	mRNA catabolic process
A	0006417	biological_process	regulation of translation
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0051607	biological_process	defense response to virus
A	0055087	cellular_component	Ski complex
A	0070478	biological_process	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
A	0070481	biological_process	nuclear-transcribed mRNA catabolic process, non-stop decay
C	0000228	cellular_component	nuclear chromosome
C	0000956	biological_process	nuclear-transcribed mRNA catabolic process
C	0003674	molecular_function	molecular_function
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0005737	cellular_component	cytoplasm
C	0006402	biological_process	mRNA catabolic process
C	0007131	biological_process	reciprocal meiotic recombination
C	0051321	biological_process	meiotic cell cycle
C	0051607	biological_process	defense response to virus
C	0055087	cellular_component	Ski complex
C	0065003	biological_process	protein-containing complex assembly
C	0065004	biological_process	protein-DNA complex assembly
C	0070478	biological_process	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
C	0070481	biological_process	nuclear-transcribed mRNA catabolic process, non-stop decay
D	0000228	cellular_component	nuclear chromosome
D	0000956	biological_process	nuclear-transcribed mRNA catabolic process
D	0003674	molecular_function	molecular_function
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005694	cellular_component	chromosome
D	0005737	cellular_component	cytoplasm
D	0006402	biological_process	mRNA catabolic process
D	0007131	biological_process	reciprocal meiotic recombination
D	0051321	biological_process	meiotic cell cycle
D	0051607	biological_process	defense response to virus
D	0055087	cellular_component	Ski complex
D	0065003	biological_process	protein-containing complex assembly
D	0065004	biological_process	protein-DNA complex assembly
D	0070478	biological_process	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
D	0070481	biological_process	nuclear-transcribed mRNA catabolic process, non-stop decay
E	0000956	biological_process	nuclear-transcribed mRNA catabolic process
E	0003674	molecular_function	molecular_function
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0006401	biological_process	RNA catabolic process
E	0006402	biological_process	mRNA catabolic process
E	0051607	biological_process	defense response to virus
E	0055087	cellular_component	Ski complex
E	0070478	biological_process	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
E	0070481	biological_process	nuclear-transcribed mRNA catabolic process, non-stop decay

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. TVSCsgDgYLKVWDN

Chain	Residue	Details
C	THR29-ASN43
C	LEU306-VAL320

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541

Chain	Residue	Details
A	ALA351

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198

Chain	Residue	Details
A	SER209

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