8Q7X

Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4)

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0016020	cellular_component	membrane
A	0016607	cellular_component	nuclear speck
A	0017070	molecular_function	U6 snRNA binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0097157	molecular_function	pre-mRNA intronic binding
A	0140492	molecular_function	metal-dependent deubiquitinase activity
A	1990904	cellular_component	ribonucleoprotein complex
B	0000166	molecular_function	nucleotide binding
B	0000354	biological_process	cis assembly of pre-catalytic spliceosome
B	0000388	biological_process	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0001649	biological_process	osteoblast differentiation
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0003724	molecular_function	RNA helicase activity
B	0004386	molecular_function	helicase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005682	cellular_component	U5 snRNP
B	0005886	cellular_component	plasma membrane
B	0005929	cellular_component	cilium
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0030532	cellular_component	small nuclear ribonucleoprotein complex
B	0042802	molecular_function	identical protein binding
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071006	cellular_component	U2-type catalytic step 1 spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
C	0000166	molecular_function	nucleotide binding
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003723	molecular_function	RNA binding
C	0003924	molecular_function	GTPase activity
C	0005515	molecular_function	protein binding
C	0005525	molecular_function	GTP binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0005829	cellular_component	cytosol
C	0006397	biological_process	mRNA processing
C	0008380	biological_process	RNA splicing
C	0015030	cellular_component	Cajal body
C	0016020	cellular_component	membrane
C	0016607	cellular_component	nuclear speck
C	0030623	molecular_function	U5 snRNA binding
C	0042220	biological_process	response to cocaine
C	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
C	0071005	cellular_component	U2-type precatalytic spliceosome
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071466	biological_process	cellular response to xenobiotic stimulus
D	0000375	biological_process	RNA splicing, via transesterification reactions
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005681	cellular_component	spliceosomal complex
D	0005682	cellular_component	U5 snRNP
D	0005732	cellular_component	sno(s)RNA-containing ribonucleoprotein complex
D	0005829	cellular_component	cytosol
D	0006396	biological_process	RNA processing
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0016607	cellular_component	nuclear speck
D	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
D	0071007	cellular_component	U2-type catalytic step 2 spliceosome
D	0071013	cellular_component	catalytic step 2 spliceosome
E	0000166	molecular_function	nucleotide binding
E	0000354	biological_process	cis assembly of pre-catalytic spliceosome
E	0000375	biological_process	RNA splicing, via transesterification reactions
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0000785	cellular_component	chromatin
E	0003676	molecular_function	nucleic acid binding
E	0003723	molecular_function	RNA binding
E	0003724	molecular_function	RNA helicase activity
E	0003729	molecular_function	mRNA binding
E	0004386	molecular_function	helicase activity
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0005682	cellular_component	U5 snRNP
E	0005694	cellular_component	chromosome
E	0005730	cellular_component	nucleolus
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
E	0062176	biological_process	R-loop processing
E	0070062	cellular_component	extracellular exosome
E	0071013	cellular_component	catalytic step 2 spliceosome
F	0000244	biological_process	spliceosomal tri-snRNP complex assembly
F	0000245	biological_process	spliceosomal complex assembly
F	0000375	biological_process	RNA splicing, via transesterification reactions
F	0000398	biological_process	mRNA splicing, via spliceosome
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005681	cellular_component	spliceosomal complex
F	0005682	cellular_component	U5 snRNP
F	0005813	cellular_component	centrosome
F	0005829	cellular_component	cytosol
F	0006396	biological_process	RNA processing
F	0006397	biological_process	mRNA processing
F	0006403	biological_process	RNA localization
F	0008380	biological_process	RNA splicing
F	0016020	cellular_component	membrane
F	0016607	cellular_component	nuclear speck
F	0030674	molecular_function	protein-macromolecule adaptor activity
F	0036064	cellular_component	ciliary basal body
F	0042802	molecular_function	identical protein binding
F	0043021	molecular_function	ribonucleoprotein complex binding
F	0045944	biological_process	positive regulation of transcription by RNA polymerase II
F	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
F	0071005	cellular_component	U2-type precatalytic spliceosome
F	0071013	cellular_component	catalytic step 2 spliceosome
G	0000244	biological_process	spliceosomal tri-snRNP complex assembly
G	0001650	cellular_component	fibrillar center
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005682	cellular_component	U5 snRNP
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006397	biological_process	mRNA processing
G	0008380	biological_process	RNA splicing
G	0016607	cellular_component	nuclear speck
G	0043021	molecular_function	ribonucleoprotein complex binding
G	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0000243	cellular_component	commitment complex
a	0000245	biological_process	spliceosomal complex assembly
a	0000387	biological_process	spliceosomal snRNP assembly
a	0000398	biological_process	mRNA splicing, via spliceosome
a	0003723	molecular_function	RNA binding
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005681	cellular_component	spliceosomal complex
a	0005682	cellular_component	U5 snRNP
a	0005684	cellular_component	U2-type spliceosomal complex
a	0005685	cellular_component	U1 snRNP
a	0005686	cellular_component	U2 snRNP
a	0005687	cellular_component	U4 snRNP
a	0005689	cellular_component	U12-type spliceosomal complex
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0006396	biological_process	RNA processing
a	0006397	biological_process	mRNA processing
a	0008380	biological_process	RNA splicing
a	0030532	cellular_component	small nuclear ribonucleoprotein complex
a	0034709	cellular_component	methylosome
a	0034715	cellular_component	pICln-Sm protein complex
a	0034719	cellular_component	SMN-Sm protein complex
a	0036261	biological_process	7-methylguanosine cap hypermethylation
a	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
a	0071005	cellular_component	U2-type precatalytic spliceosome
a	0071007	cellular_component	U2-type catalytic step 2 spliceosome
a	0071011	cellular_component	precatalytic spliceosome
a	0071013	cellular_component	catalytic step 2 spliceosome
a	0097526	cellular_component	spliceosomal tri-snRNP complex
a	1903241	biological_process	U2-type prespliceosome assembly
a	1990446	molecular_function	U1 snRNP binding
a	1990904	cellular_component	ribonucleoprotein complex
b	0000387	biological_process	spliceosomal snRNP assembly
b	0000398	biological_process	mRNA splicing, via spliceosome
b	0003723	molecular_function	RNA binding
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0005654	cellular_component	nucleoplasm
b	0005681	cellular_component	spliceosomal complex
b	0005682	cellular_component	U5 snRNP
b	0005683	cellular_component	U7 snRNP
b	0005684	cellular_component	U2-type spliceosomal complex
b	0005685	cellular_component	U1 snRNP
b	0005686	cellular_component	U2 snRNP
b	0005687	cellular_component	U4 snRNP
b	0005689	cellular_component	U12-type spliceosomal complex
b	0005697	cellular_component	telomerase holoenzyme complex
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0006397	biological_process	mRNA processing
b	0006479	biological_process	protein methylation
b	0008380	biological_process	RNA splicing
b	0030532	cellular_component	small nuclear ribonucleoprotein complex
b	0034709	cellular_component	methylosome
b	0034719	cellular_component	SMN-Sm protein complex
b	0036261	biological_process	7-methylguanosine cap hypermethylation
b	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
b	0070034	molecular_function	telomerase RNA binding
b	0070990	molecular_function	snRNP binding
b	0071004	cellular_component	U2-type prespliceosome
b	0071005	cellular_component	U2-type precatalytic spliceosome
b	0071007	cellular_component	U2-type catalytic step 2 spliceosome
b	0071013	cellular_component	catalytic step 2 spliceosome
b	0071204	cellular_component	histone pre-mRNA 3'end processing complex
b	0071208	molecular_function	histone pre-mRNA DCP binding
b	1903241	biological_process	U2-type prespliceosome assembly
b	1990446	molecular_function	U1 snRNP binding
b	1990447	molecular_function	U2 snRNP binding
b	1990904	cellular_component	ribonucleoprotein complex
c	0000245	biological_process	spliceosomal complex assembly
c	0000387	biological_process	spliceosomal snRNP assembly
c	0000398	biological_process	mRNA splicing, via spliceosome
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0005634	cellular_component	nucleus
c	0005654	cellular_component	nucleoplasm
c	0005681	cellular_component	spliceosomal complex
c	0005682	cellular_component	U5 snRNP
c	0005684	cellular_component	U2-type spliceosomal complex
c	0005685	cellular_component	U1 snRNP
c	0005686	cellular_component	U2 snRNP
c	0005687	cellular_component	U4 snRNP
c	0005689	cellular_component	U12-type spliceosomal complex
c	0005829	cellular_component	cytosol
c	0006397	biological_process	mRNA processing
c	0008380	biological_process	RNA splicing
c	0030532	cellular_component	small nuclear ribonucleoprotein complex
c	0034709	cellular_component	methylosome
c	0034715	cellular_component	pICln-Sm protein complex
c	0034719	cellular_component	SMN-Sm protein complex
c	0036261	biological_process	7-methylguanosine cap hypermethylation
c	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
c	0070062	cellular_component	extracellular exosome
c	0071005	cellular_component	U2-type precatalytic spliceosome
c	0071007	cellular_component	U2-type catalytic step 2 spliceosome
c	0071011	cellular_component	precatalytic spliceosome
c	0071013	cellular_component	catalytic step 2 spliceosome
c	0097525	cellular_component	spliceosomal snRNP complex
c	1903241	biological_process	U2-type prespliceosome assembly
c	1990904	cellular_component	ribonucleoprotein complex
d	0000243	cellular_component	commitment complex
d	0000387	biological_process	spliceosomal snRNP assembly
d	0000398	biological_process	mRNA splicing, via spliceosome
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005654	cellular_component	nucleoplasm
d	0005681	cellular_component	spliceosomal complex
d	0005682	cellular_component	U5 snRNP
d	0005683	cellular_component	U7 snRNP
d	0005684	cellular_component	U2-type spliceosomal complex
d	0005685	cellular_component	U1 snRNP
d	0005686	cellular_component	U2 snRNP
d	0005687	cellular_component	U4 snRNP
d	0005689	cellular_component	U12-type spliceosomal complex
d	0005697	cellular_component	telomerase holoenzyme complex
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0006396	biological_process	RNA processing
d	0006397	biological_process	mRNA processing
d	0006479	biological_process	protein methylation
d	0008380	biological_process	RNA splicing
d	0016604	cellular_component	nuclear body
d	0019899	molecular_function	enzyme binding
d	0030532	cellular_component	small nuclear ribonucleoprotein complex
d	0034709	cellular_component	methylosome
d	0034715	cellular_component	pICln-Sm protein complex
d	0034719	cellular_component	SMN-Sm protein complex
d	0036261	biological_process	7-methylguanosine cap hypermethylation
d	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
d	0070034	molecular_function	telomerase RNA binding
d	0071005	cellular_component	U2-type precatalytic spliceosome
d	0071007	cellular_component	U2-type catalytic step 2 spliceosome
d	0071011	cellular_component	precatalytic spliceosome
d	0071013	cellular_component	catalytic step 2 spliceosome
d	0071208	molecular_function	histone pre-mRNA DCP binding
d	0071209	molecular_function	U7 snRNA binding
d	0097526	cellular_component	spliceosomal tri-snRNP complex
d	1903241	biological_process	U2-type prespliceosome assembly
d	1990904	cellular_component	ribonucleoprotein complex
e	0000245	biological_process	spliceosomal complex assembly
e	0000387	biological_process	spliceosomal snRNP assembly
e	0000398	biological_process	mRNA splicing, via spliceosome
e	0003723	molecular_function	RNA binding
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005654	cellular_component	nucleoplasm
e	0005681	cellular_component	spliceosomal complex
e	0005682	cellular_component	U5 snRNP
e	0005683	cellular_component	U7 snRNP
e	0005684	cellular_component	U2-type spliceosomal complex
e	0005685	cellular_component	U1 snRNP
e	0005686	cellular_component	U2 snRNP
e	0005687	cellular_component	U4 snRNP
e	0005689	cellular_component	U12-type spliceosomal complex
e	0005697	cellular_component	telomerase holoenzyme complex
e	0005829	cellular_component	cytosol
e	0006397	biological_process	mRNA processing
e	0008380	biological_process	RNA splicing
e	0030532	cellular_component	small nuclear ribonucleoprotein complex
e	0034709	cellular_component	methylosome
e	0034715	cellular_component	pICln-Sm protein complex
e	0034719	cellular_component	SMN-Sm protein complex
e	0036261	biological_process	7-methylguanosine cap hypermethylation
e	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
e	0071005	cellular_component	U2-type precatalytic spliceosome
e	0071007	cellular_component	U2-type catalytic step 2 spliceosome
e	0071011	cellular_component	precatalytic spliceosome
e	0071013	cellular_component	catalytic step 2 spliceosome
e	1903241	biological_process	U2-type prespliceosome assembly
e	1990904	cellular_component	ribonucleoprotein complex
f	0000387	biological_process	spliceosomal snRNP assembly
f	0000398	biological_process	mRNA splicing, via spliceosome
f	0003723	molecular_function	RNA binding
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005654	cellular_component	nucleoplasm
f	0005681	cellular_component	spliceosomal complex
f	0005682	cellular_component	U5 snRNP
f	0005683	cellular_component	U7 snRNP
f	0005684	cellular_component	U2-type spliceosomal complex
f	0005685	cellular_component	U1 snRNP
f	0005686	cellular_component	U2 snRNP
f	0005687	cellular_component	U4 snRNP
f	0005689	cellular_component	U12-type spliceosomal complex
f	0005829	cellular_component	cytosol
f	0006397	biological_process	mRNA processing
f	0008380	biological_process	RNA splicing
f	0022618	biological_process	protein-RNA complex assembly
f	0030532	cellular_component	small nuclear ribonucleoprotein complex
f	0034709	cellular_component	methylosome
f	0034715	cellular_component	pICln-Sm protein complex
f	0034719	cellular_component	SMN-Sm protein complex
f	0036261	biological_process	7-methylguanosine cap hypermethylation
f	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
f	0071005	cellular_component	U2-type precatalytic spliceosome
f	0071007	cellular_component	U2-type catalytic step 2 spliceosome
f	0071013	cellular_component	catalytic step 2 spliceosome
f	1903241	biological_process	U2-type prespliceosome assembly
f	1990904	cellular_component	ribonucleoprotein complex
g	0000245	biological_process	spliceosomal complex assembly
g	0000387	biological_process	spliceosomal snRNP assembly
g	0000398	biological_process	mRNA splicing, via spliceosome
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0005654	cellular_component	nucleoplasm
g	0005681	cellular_component	spliceosomal complex
g	0005682	cellular_component	U5 snRNP
g	0005683	cellular_component	U7 snRNP
g	0005684	cellular_component	U2-type spliceosomal complex
g	0005685	cellular_component	U1 snRNP
g	0005686	cellular_component	U2 snRNP
g	0005687	cellular_component	U4 snRNP
g	0005689	cellular_component	U12-type spliceosomal complex
g	0005829	cellular_component	cytosol
g	0006397	biological_process	mRNA processing
g	0008380	biological_process	RNA splicing
g	0030532	cellular_component	small nuclear ribonucleoprotein complex
g	0034709	cellular_component	methylosome
g	0034719	cellular_component	SMN-Sm protein complex
g	0036261	biological_process	7-methylguanosine cap hypermethylation
g	0043186	cellular_component	P granule
g	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
g	0071004	cellular_component	U2-type prespliceosome
g	0071005	cellular_component	U2-type precatalytic spliceosome
g	0071007	cellular_component	U2-type catalytic step 2 spliceosome
g	0071011	cellular_component	precatalytic spliceosome
g	0071013	cellular_component	catalytic step 2 spliceosome
g	0097526	cellular_component	spliceosomal tri-snRNP complex
g	1903241	biological_process	U2-type prespliceosome assembly
g	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADRmI

Chain	Residue	Details
E	VAL547-ILE555

---

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LASAgfDrLILLWNV

Chain	Residue	Details
D	LEU81-VAL95
D	LEU124-SER138
D	VAL167-ILE181
D	ILE208-LEU222
D	ILE300-THR314

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	131
Details	Domain: {"description":"MPN","evidences":[{"source":"PROSITE-ProRule","id":"PRU01182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	491
Details	Region: {"description":"Reverse transcriptase homology domain"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	171
Details	Region: {"description":"Restriction endonuclease homology domain"}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	34
Details	Region: {"description":"Required for interaction with EFTUD2 and SNRNP200","evidences":[{"source":"PubMed","id":"17317632","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N6,N6-dimethyllysine","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	183
Details	Domain: {"description":"Helicase ATP-binding 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	237
Details	Domain: {"description":"Helicase C-terminal 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	305
Details	Domain: {"description":"SEC63 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	175
Details	Domain: {"description":"Helicase ATP-binding 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	208
Details	Domain: {"description":"Helicase C-terminal 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	312
Details	Domain: {"description":"SEC63 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	3
Details	Motif: {"description":"DEIH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	3
Details	Motif: {"description":"DEVH box"}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23045696","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4F93","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"F1LNJ2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q6P4T2","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	282
Details	Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	39
Details	Repeat: {"description":"WD 1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	39
Details	Repeat: {"description":"WD 2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	40
Details	Repeat: {"description":"WD 3"}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	39
Details	Repeat: {"description":"WD 4"}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	39
Details	Repeat: {"description":"WD 5"}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	39
Details	Repeat: {"description":"WD 6"}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	32
Details	Repeat: {"description":"WD 7"}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	28
Details	Motif: {"description":"Q motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00552","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	3
Details	Motif: {"description":"DEAD box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	216
Details	Domain: {"description":"Sm","evidences":[{"source":"PROSITE-ProRule","id":"PRU01346","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---