8Q5H

Human KMN network (outer kinetochore)

Functional Information from GO Data

Chain	GOid	namespace	contents
5	0007059	biological_process	chromosome segregation
5	0031262	cellular_component	Ndc80 complex
A	0000070	biological_process	mitotic sister chromatid segregation
A	0000278	biological_process	mitotic cell cycle
A	0000444	cellular_component	MIS12/MIND type complex
A	0000775	cellular_component	chromosome, centromeric region
A	0000776	cellular_component	kinetochore
A	0000922	cellular_component	spindle pole
A	0000940	cellular_component	outer kinetochore
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005829	cellular_component	cytosol
A	0007059	biological_process	chromosome segregation
A	0008608	biological_process	attachment of spindle microtubules to kinetochore
A	0051301	biological_process	cell division
A	0051315	biological_process	attachment of mitotic spindle microtubules to kinetochore
A	0051382	biological_process	kinetochore assembly
B	0000444	cellular_component	MIS12/MIND type complex
B	0000776	cellular_component	kinetochore
B	0000922	cellular_component	spindle pole
B	0000940	cellular_component	outer kinetochore
B	0003713	molecular_function	transcription coactivator activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005667	cellular_component	transcription regulator complex
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006366	biological_process	transcription by RNA polymerase II
B	0007059	biological_process	chromosome segregation
B	0008608	biological_process	attachment of spindle microtubules to kinetochore
B	0043522	molecular_function	leucine zipper domain binding
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0051301	biological_process	cell division
D	0000444	cellular_component	MIS12/MIND type complex
D	0000776	cellular_component	kinetochore
D	0000922	cellular_component	spindle pole
D	0000940	cellular_component	outer kinetochore
D	0001650	cellular_component	fibrillar center
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005829	cellular_component	cytosol
D	0007059	biological_process	chromosome segregation
D	0008608	biological_process	attachment of spindle microtubules to kinetochore
D	0016604	cellular_component	nuclear body
D	0035578	cellular_component	azurophil granule lumen
D	0051301	biological_process	cell division
K	0008608	biological_process	attachment of spindle microtubules to kinetochore
K	0034501	biological_process	protein localization to kinetochore
N	0000070	biological_process	mitotic sister chromatid segregation
N	0000444	cellular_component	MIS12/MIND type complex
N	0000776	cellular_component	kinetochore
N	0000922	cellular_component	spindle pole
N	0000940	cellular_component	outer kinetochore
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005829	cellular_component	cytosol
N	0007059	biological_process	chromosome segregation
N	0008608	biological_process	attachment of spindle microtubules to kinetochore
N	0016607	cellular_component	nuclear speck
N	0051301	biological_process	cell division

Functional Information from PROSITE/UniProt

site_id	PS00092
Number of Residues	7
Details	N6_MTASE N-6 Adenine-specific DNA methylases signature. VVLDPPW

Chain	Residue	Details
N	VAL8-TRP14

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	79
Details	Region: {"description":"Interaction with the C-terminus of SPBC24"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	149
Details	Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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