8Q3B

The closed state of the ASFV apo-RNA polymerase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019083	biological_process	viral transcription
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0039695	biological_process	DNA-templated viral transcription
A	0044423	cellular_component	virion component
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0006351	biological_process	DNA-templated transcription
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019083	biological_process	viral transcription
B	0030430	cellular_component	host cell cytoplasm
B	0032549	molecular_function	ribonucleoside binding
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0039695	biological_process	DNA-templated viral transcription
B	0044423	cellular_component	virion component
B	0046872	molecular_function	metal ion binding
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0006351	biological_process	DNA-templated transcription
C	0019083	biological_process	viral transcription
C	0030430	cellular_component	host cell cytoplasm
C	0044423	cellular_component	virion component
C	0046983	molecular_function	protein dimerization activity
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0019083	biological_process	viral transcription
D	0030430	cellular_component	host cell cytoplasm
D	0044423	cellular_component	virion component
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0019083	biological_process	viral transcription
E	0030430	cellular_component	host cell cytoplasm
E	0044423	cellular_component	virion component
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0001054	molecular_function	RNA polymerase I activity
F	0001055	molecular_function	RNA polymerase II activity
F	0001056	molecular_function	RNA polymerase III activity
F	0003677	molecular_function	DNA binding
F	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
F	0006351	biological_process	DNA-templated transcription
F	0006360	biological_process	transcription by RNA polymerase I
F	0006366	biological_process	transcription by RNA polymerase II
F	0019083	biological_process	viral transcription
F	0030430	cellular_component	host cell cytoplasm
F	0042797	biological_process	tRNA transcription by RNA polymerase III
F	0044423	cellular_component	virion component
I	0044423	cellular_component	virion component
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
J	0006351	biological_process	DNA-templated transcription
J	0008270	molecular_function	zinc ion binding
J	0019083	biological_process	viral transcription
J	0030430	cellular_component	host cell cytoplasm
J	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCKAVH

Chain	Residue	Details
A	TYR135-HIS141

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site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TtFEaTRlVAvRAqQ

Chain	Residue	Details
F	THR72-GLN86

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site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. LIPVvCFTCG

Chain	Residue	Details
J	LEU2-GLY11

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site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKMSSrSGNKGI

Chain	Residue	Details
B	GLY993-ILE1005

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P22139

Chain	Residue	Details
J	CYS7
J	CYS10
J	CYS65
J	CYS66

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