8PVG

Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004356	molecular_function	glutamine synthetase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006542	biological_process	glutamine biosynthetic process
A	0009314	biological_process	response to radiation
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0016879	molecular_function	ligase activity, forming carbon-nitrogen bonds
A	0019676	biological_process	ammonia assimilation cycle
A	0019740	biological_process	nitrogen utilization
A	0042802	molecular_function	identical protein binding
A	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00180
Number of Residues	19
Details	GLNA_1 Glutamine synthetase signature 1. FDGSSiggwkginESDmvL

Chain	Residue	Details
A	PHE50-LEU68

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site_id	PS00181
Number of Residues	16
Details	GLNA_ATP Glutamine synthetase putative ATP-binding region signature. KPMfgd..NGSGmHchmS

Chain	Residue	Details
A	LYS259-SER274

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P9WN39

Chain	Residue	Details
A	GLU130
A	GLU132
A	GLU213
A	GLU221
A	HIS270
A	ARG340
A	ARG345
A	GLU358

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0A1P6

Chain	Residue	Details
A	GLU208
A	ASN265
A	HIS272
A	ARG322
A	GLU328
A	ARG360

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P12425

Chain	Residue	Details
A	GLY266

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P77961

Chain	Residue	Details
A	SER274
A	LYS353

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: O-AMP-tyrosine => ECO:0000269|PubMed:4904088, ECO:0000269|PubMed:5543675

Chain	Residue	Details
A	PHE398

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