8PPF

Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with beta-D-glucopyranosyl 1,3,4-trisphosphate/AMP-PNP/Mg

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016301	molecular_function	kinase activity
A	0032958	biological_process	inositol phosphate biosynthetic process
B	0016301	molecular_function	kinase activity
B	0032958	biological_process	inositol phosphate biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15350214, ECO:0007744|PDB:1W2D

Chain	Residue	Details
A	SER197
B	SER197

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:15350214, ECO:0007744|PDB:1W2C

Chain	Residue	Details
A	LYS209
B	GLN249
B	ASP262
B	LYS264
B	ARG285
B	LYS336
B	ASP416
B	LYS419
A	GLN249
A	ASP262
A	LYS264
A	ARG285
A	LYS336
A	ASP416
A	LYS419
B	LYS209

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15350214

Chain	Residue	Details
A	LYS312
B	LYS312

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER197
B	SER197

---