8PPC
Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with L-chiro-inositol 2,3,5-trisphosphate/ATP/Mn
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15350214, ECO:0007744|PDB:1W2D |
| Chain | Residue | Details |
| A | SER197 | |
| B | SER197 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15350214, ECO:0007744|PDB:1W2C |
| Chain | Residue | Details |
| A | LYS209 | |
| B | GLN249 | |
| B | ASP262 | |
| B | LYS264 | |
| B | ARG285 | |
| B | LYS336 | |
| B | ASP416 | |
| B | LYS419 | |
| A | GLN249 | |
| A | ASP262 | |
| A | LYS264 | |
| A | ARG285 | |
| A | LYS336 | |
| A | ASP416 | |
| A | LYS419 | |
| B | LYS209 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15350214 |
| Chain | Residue | Details |
| A | LYS312 | |
| B | LYS312 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER197 | |
| B | SER197 |
