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8PK1

Cas1-Cas2 CRISPR integrase bound to prespacer DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system

Functional Information from GO Data
ChainGOidnamespacecontents
A0004518molecular_functionnuclease activity
A0004519molecular_functionendonuclease activity
A0004521molecular_functionRNA endonuclease activity
A0016787molecular_functionhydrolase activity
A0043571biological_processmaintenance of CRISPR repeat elements
A0046872molecular_functionmetal ion binding
A0051607biological_processdefense response to virus
B0003676molecular_functionnucleic acid binding
B0003677molecular_functionDNA binding
B0004518molecular_functionnuclease activity
B0004519molecular_functionendonuclease activity
B0004520molecular_functionDNA endonuclease activity
B0016787molecular_functionhydrolase activity
B0043571biological_processmaintenance of CRISPR repeat elements
B0046872molecular_functionmetal ion binding
B0051607biological_processdefense response to virus
C0003676molecular_functionnucleic acid binding
C0003677molecular_functionDNA binding
C0004518molecular_functionnuclease activity
C0004519molecular_functionendonuclease activity
C0004520molecular_functionDNA endonuclease activity
C0016787molecular_functionhydrolase activity
C0043571biological_processmaintenance of CRISPR repeat elements
C0046872molecular_functionmetal ion binding
C0051607biological_processdefense response to virus
D0004518molecular_functionnuclease activity
D0004519molecular_functionendonuclease activity
D0004521molecular_functionRNA endonuclease activity
D0016787molecular_functionhydrolase activity
D0043571biological_processmaintenance of CRISPR repeat elements
D0046872molecular_functionmetal ion binding
D0051607biological_processdefense response to virus
E0003676molecular_functionnucleic acid binding
E0003677molecular_functionDNA binding
E0004518molecular_functionnuclease activity
E0004519molecular_functionendonuclease activity
E0004520molecular_functionDNA endonuclease activity
E0016787molecular_functionhydrolase activity
E0043571biological_processmaintenance of CRISPR repeat elements
E0046872molecular_functionmetal ion binding
E0051607biological_processdefense response to virus
F0003676molecular_functionnucleic acid binding
F0003677molecular_functionDNA binding
F0004518molecular_functionnuclease activity
F0004519molecular_functionendonuclease activity
F0004520molecular_functionDNA endonuclease activity
F0016787molecular_functionhydrolase activity
F0043571biological_processmaintenance of CRISPR repeat elements
F0046872molecular_functionmetal ion binding
F0051607biological_processdefense response to virus
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
BGLU149
FGLU149
FHIS205
FGLU220
BHIS205
BGLU220
CGLU149
CHIS205
CGLU220
EGLU149
EHIS205
EGLU220

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PDB entries from 2025-06-11

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