8PIU

60-meric complex of dihydrolipoamide acetyltransferase (E2) of the human pyruvate dehydrogenase complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
A	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
A	0006090	biological_process	pyruvate metabolic process
A	0016746	molecular_function	acyltransferase activity
A	0045254	cellular_component	pyruvate dehydrogenase complex
AA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
AA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
AA	0006090	biological_process	pyruvate metabolic process
AA	0016746	molecular_function	acyltransferase activity
AA	0045254	cellular_component	pyruvate dehydrogenase complex
AB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
AB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
AB	0006090	biological_process	pyruvate metabolic process
AB	0016746	molecular_function	acyltransferase activity
AB	0045254	cellular_component	pyruvate dehydrogenase complex
B	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
B	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
B	0006090	biological_process	pyruvate metabolic process
B	0016746	molecular_function	acyltransferase activity
B	0045254	cellular_component	pyruvate dehydrogenase complex
BA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
BA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
BA	0006090	biological_process	pyruvate metabolic process
BA	0016746	molecular_function	acyltransferase activity
BA	0045254	cellular_component	pyruvate dehydrogenase complex
BB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
BB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
BB	0006090	biological_process	pyruvate metabolic process
BB	0016746	molecular_function	acyltransferase activity
BB	0045254	cellular_component	pyruvate dehydrogenase complex
C	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
C	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
C	0006090	biological_process	pyruvate metabolic process
C	0016746	molecular_function	acyltransferase activity
C	0045254	cellular_component	pyruvate dehydrogenase complex
CA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
CA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
CA	0006090	biological_process	pyruvate metabolic process
CA	0016746	molecular_function	acyltransferase activity
CA	0045254	cellular_component	pyruvate dehydrogenase complex
CB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
CB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
CB	0006090	biological_process	pyruvate metabolic process
CB	0016746	molecular_function	acyltransferase activity
CB	0045254	cellular_component	pyruvate dehydrogenase complex
D	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
D	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
D	0006090	biological_process	pyruvate metabolic process
D	0016746	molecular_function	acyltransferase activity
D	0045254	cellular_component	pyruvate dehydrogenase complex
DA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
DA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
DA	0006090	biological_process	pyruvate metabolic process
DA	0016746	molecular_function	acyltransferase activity
DA	0045254	cellular_component	pyruvate dehydrogenase complex
DB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
DB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
DB	0006090	biological_process	pyruvate metabolic process
DB	0016746	molecular_function	acyltransferase activity
DB	0045254	cellular_component	pyruvate dehydrogenase complex
E	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
E	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
E	0006090	biological_process	pyruvate metabolic process
E	0016746	molecular_function	acyltransferase activity
E	0045254	cellular_component	pyruvate dehydrogenase complex
EA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
EA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
EA	0006090	biological_process	pyruvate metabolic process
EA	0016746	molecular_function	acyltransferase activity
EA	0045254	cellular_component	pyruvate dehydrogenase complex
EB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
EB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
EB	0006090	biological_process	pyruvate metabolic process
EB	0016746	molecular_function	acyltransferase activity
EB	0045254	cellular_component	pyruvate dehydrogenase complex
F	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
F	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
F	0006090	biological_process	pyruvate metabolic process
F	0016746	molecular_function	acyltransferase activity
F	0045254	cellular_component	pyruvate dehydrogenase complex
FA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
FA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
FA	0006090	biological_process	pyruvate metabolic process
FA	0016746	molecular_function	acyltransferase activity
FA	0045254	cellular_component	pyruvate dehydrogenase complex
FB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
FB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
FB	0006090	biological_process	pyruvate metabolic process
FB	0016746	molecular_function	acyltransferase activity
FB	0045254	cellular_component	pyruvate dehydrogenase complex
G	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
G	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
G	0006090	biological_process	pyruvate metabolic process
G	0016746	molecular_function	acyltransferase activity
G	0045254	cellular_component	pyruvate dehydrogenase complex
GA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
GA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
GA	0006090	biological_process	pyruvate metabolic process
GA	0016746	molecular_function	acyltransferase activity
GA	0045254	cellular_component	pyruvate dehydrogenase complex
GB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
GB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
GB	0006090	biological_process	pyruvate metabolic process
GB	0016746	molecular_function	acyltransferase activity
GB	0045254	cellular_component	pyruvate dehydrogenase complex
H	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
H	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
H	0006090	biological_process	pyruvate metabolic process
H	0016746	molecular_function	acyltransferase activity
H	0045254	cellular_component	pyruvate dehydrogenase complex
HA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
HA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
HA	0006090	biological_process	pyruvate metabolic process
HA	0016746	molecular_function	acyltransferase activity
HA	0045254	cellular_component	pyruvate dehydrogenase complex
HB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
HB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
HB	0006090	biological_process	pyruvate metabolic process
HB	0016746	molecular_function	acyltransferase activity
HB	0045254	cellular_component	pyruvate dehydrogenase complex
I	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
I	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
I	0006090	biological_process	pyruvate metabolic process
I	0016746	molecular_function	acyltransferase activity
I	0045254	cellular_component	pyruvate dehydrogenase complex
IA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
IA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
IA	0006090	biological_process	pyruvate metabolic process
IA	0016746	molecular_function	acyltransferase activity
IA	0045254	cellular_component	pyruvate dehydrogenase complex
IB	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
IB	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
IB	0006090	biological_process	pyruvate metabolic process
IB	0016746	molecular_function	acyltransferase activity
IB	0045254	cellular_component	pyruvate dehydrogenase complex
J	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
J	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
J	0006090	biological_process	pyruvate metabolic process
J	0016746	molecular_function	acyltransferase activity
J	0045254	cellular_component	pyruvate dehydrogenase complex
JA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
JA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
JA	0006090	biological_process	pyruvate metabolic process
JA	0016746	molecular_function	acyltransferase activity
JA	0045254	cellular_component	pyruvate dehydrogenase complex
K	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
K	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
K	0006090	biological_process	pyruvate metabolic process
K	0016746	molecular_function	acyltransferase activity
K	0045254	cellular_component	pyruvate dehydrogenase complex
KA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
KA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
KA	0006090	biological_process	pyruvate metabolic process
KA	0016746	molecular_function	acyltransferase activity
KA	0045254	cellular_component	pyruvate dehydrogenase complex
L	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
L	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
L	0006090	biological_process	pyruvate metabolic process
L	0016746	molecular_function	acyltransferase activity
L	0045254	cellular_component	pyruvate dehydrogenase complex
LA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
LA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
LA	0006090	biological_process	pyruvate metabolic process
LA	0016746	molecular_function	acyltransferase activity
LA	0045254	cellular_component	pyruvate dehydrogenase complex
M	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
M	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
M	0006090	biological_process	pyruvate metabolic process
M	0016746	molecular_function	acyltransferase activity
M	0045254	cellular_component	pyruvate dehydrogenase complex
MA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
MA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
MA	0006090	biological_process	pyruvate metabolic process
MA	0016746	molecular_function	acyltransferase activity
MA	0045254	cellular_component	pyruvate dehydrogenase complex
N	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
N	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
N	0006090	biological_process	pyruvate metabolic process
N	0016746	molecular_function	acyltransferase activity
N	0045254	cellular_component	pyruvate dehydrogenase complex
NA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
NA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
NA	0006090	biological_process	pyruvate metabolic process
NA	0016746	molecular_function	acyltransferase activity
NA	0045254	cellular_component	pyruvate dehydrogenase complex
O	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
O	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
O	0006090	biological_process	pyruvate metabolic process
O	0016746	molecular_function	acyltransferase activity
O	0045254	cellular_component	pyruvate dehydrogenase complex
OA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
OA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
OA	0006090	biological_process	pyruvate metabolic process
OA	0016746	molecular_function	acyltransferase activity
OA	0045254	cellular_component	pyruvate dehydrogenase complex
P	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
P	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
P	0006090	biological_process	pyruvate metabolic process
P	0016746	molecular_function	acyltransferase activity
P	0045254	cellular_component	pyruvate dehydrogenase complex
PA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
PA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
PA	0006090	biological_process	pyruvate metabolic process
PA	0016746	molecular_function	acyltransferase activity
PA	0045254	cellular_component	pyruvate dehydrogenase complex
Q	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
Q	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
Q	0006090	biological_process	pyruvate metabolic process
Q	0016746	molecular_function	acyltransferase activity
Q	0045254	cellular_component	pyruvate dehydrogenase complex
QA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
QA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
QA	0006090	biological_process	pyruvate metabolic process
QA	0016746	molecular_function	acyltransferase activity
QA	0045254	cellular_component	pyruvate dehydrogenase complex
R	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
R	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
R	0006090	biological_process	pyruvate metabolic process
R	0016746	molecular_function	acyltransferase activity
R	0045254	cellular_component	pyruvate dehydrogenase complex
RA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
RA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
RA	0006090	biological_process	pyruvate metabolic process
RA	0016746	molecular_function	acyltransferase activity
RA	0045254	cellular_component	pyruvate dehydrogenase complex
S	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
S	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
S	0006090	biological_process	pyruvate metabolic process
S	0016746	molecular_function	acyltransferase activity
S	0045254	cellular_component	pyruvate dehydrogenase complex
SA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
SA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
SA	0006090	biological_process	pyruvate metabolic process
SA	0016746	molecular_function	acyltransferase activity
SA	0045254	cellular_component	pyruvate dehydrogenase complex
T	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
T	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
T	0006090	biological_process	pyruvate metabolic process
T	0016746	molecular_function	acyltransferase activity
T	0045254	cellular_component	pyruvate dehydrogenase complex
TA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
TA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
TA	0006090	biological_process	pyruvate metabolic process
TA	0016746	molecular_function	acyltransferase activity
TA	0045254	cellular_component	pyruvate dehydrogenase complex
UA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
UA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
UA	0006090	biological_process	pyruvate metabolic process
UA	0016746	molecular_function	acyltransferase activity
UA	0045254	cellular_component	pyruvate dehydrogenase complex
V	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
V	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
V	0006090	biological_process	pyruvate metabolic process
V	0016746	molecular_function	acyltransferase activity
V	0045254	cellular_component	pyruvate dehydrogenase complex
VA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
VA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
VA	0006090	biological_process	pyruvate metabolic process
VA	0016746	molecular_function	acyltransferase activity
VA	0045254	cellular_component	pyruvate dehydrogenase complex
W	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
W	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
W	0006090	biological_process	pyruvate metabolic process
W	0016746	molecular_function	acyltransferase activity
W	0045254	cellular_component	pyruvate dehydrogenase complex
WA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
WA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
WA	0006090	biological_process	pyruvate metabolic process
WA	0016746	molecular_function	acyltransferase activity
WA	0045254	cellular_component	pyruvate dehydrogenase complex
X	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
X	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
X	0006090	biological_process	pyruvate metabolic process
X	0016746	molecular_function	acyltransferase activity
X	0045254	cellular_component	pyruvate dehydrogenase complex
XA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
XA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
XA	0006090	biological_process	pyruvate metabolic process
XA	0016746	molecular_function	acyltransferase activity
XA	0045254	cellular_component	pyruvate dehydrogenase complex
Y	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
Y	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
Y	0006090	biological_process	pyruvate metabolic process
Y	0016746	molecular_function	acyltransferase activity
Y	0045254	cellular_component	pyruvate dehydrogenase complex
YA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
YA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
YA	0006090	biological_process	pyruvate metabolic process
YA	0016746	molecular_function	acyltransferase activity
YA	0045254	cellular_component	pyruvate dehydrogenase complex
Z	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
Z	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
Z	0006090	biological_process	pyruvate metabolic process
Z	0016746	molecular_function	acyltransferase activity
Z	0045254	cellular_component	pyruvate dehydrogenase complex
ZA	0004742	molecular_function	dihydrolipoyllysine-residue acetyltransferase activity
ZA	0006086	biological_process	pyruvate decarboxylation to acetyl-CoA
ZA	0006090	biological_process	pyruvate metabolic process
ZA	0016746	molecular_function	acyltransferase activity
ZA	0045254	cellular_component	pyruvate dehydrogenase complex

Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	12
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PalSPtMTMGTV

Chain	Residue	Details
B	PRO224-VAL235

---

site_id	PS00189
Number of Residues	30
Details	LIPOYL 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. GdkInegDLIaeVETdKATvgFesleeCyM

Chain	Residue	Details
B	GLY116-MET145
B	GLY243-LEU272

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	120
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q9N0F1

Chain	Residue	Details
B	HIS620
CB	ASP624
PA	ASP624
QA	HIS620
QA	ASP624
RA	HIS620
RA	ASP624
SA	HIS620
SA	ASP624
TA	HIS620
TA	ASP624
UA	HIS620
DB	HIS620
UA	ASP624
VA	HIS620
VA	ASP624
WA	HIS620
WA	ASP624
XA	HIS620
XA	ASP624
YA	HIS620
YA	ASP624
ZA	HIS620
DB	ASP624
ZA	ASP624
EB	HIS620
EB	ASP624
FB	HIS620
FB	ASP624
GB	HIS620
GB	ASP624
HB	HIS620
B	ASP624
HB	ASP624
IB	HIS620
IB	ASP624
C	HIS620
C	ASP624
D	HIS620
D	ASP624
E	HIS620
E	ASP624
F	HIS620
AB	HIS620
F	ASP624
G	HIS620
G	ASP624
H	HIS620
H	ASP624
I	HIS620
I	ASP624
J	HIS620
J	ASP624
K	HIS620
AB	ASP624
K	ASP624
L	HIS620
L	ASP624
M	HIS620
M	ASP624
N	HIS620
N	ASP624
O	HIS620
O	ASP624
P	HIS620
A	HIS620
P	ASP624
Q	HIS620
Q	ASP624
R	HIS620
R	ASP624
BA	HIS620
BA	ASP624
S	HIS620
S	ASP624
T	HIS620
A	ASP624
T	ASP624
V	HIS620
V	ASP624
W	HIS620
W	ASP624
X	HIS620
X	ASP624
Y	HIS620
Y	ASP624
Z	HIS620
BB	HIS620
Z	ASP624
AA	HIS620
AA	ASP624
CA	HIS620
CA	ASP624
DA	HIS620
DA	ASP624
EA	HIS620
EA	ASP624
FA	HIS620
BB	ASP624
FA	ASP624
GA	HIS620
GA	ASP624
HA	HIS620
HA	ASP624
IA	HIS620
IA	ASP624
JA	HIS620
JA	ASP624
KA	HIS620
CB	HIS620
KA	ASP624
LA	HIS620
LA	ASP624
MA	HIS620
MA	ASP624
NA	HIS620
NA	ASP624
OA	HIS620
OA	ASP624
PA	HIS620

---

site_id	SWS_FT_FI2
Number of Residues	300
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P11181

Chain	Residue	Details
B	ARG461
AB	GLY591
K	GLY591
L	ARG461
L	SER475
L	SER566
L	ASN567
L	GLY591
M	ARG461
M	SER475
M	SER566
M	ASN567
A	ARG461
M	GLY591
N	ARG461
N	SER475
N	SER566
N	ASN567
N	GLY591
O	ARG461
O	SER475
O	SER566
O	ASN567
A	SER475
O	GLY591
P	ARG461
P	SER475
P	SER566
P	ASN567
P	GLY591
Q	ARG461
Q	SER475
Q	SER566
Q	ASN567
A	SER566
Q	GLY591
R	ARG461
R	SER475
R	SER566
R	ASN567
R	GLY591
BA	ARG461
BA	SER475
BA	SER566
BA	ASN567
A	ASN567
BA	GLY591
S	ARG461
S	SER475
S	SER566
S	ASN567
S	GLY591
T	ARG461
T	SER475
T	SER566
T	ASN567
A	GLY591
T	GLY591
V	ARG461
V	SER475
V	SER566
V	ASN567
V	GLY591
W	ARG461
W	SER475
W	SER566
W	ASN567
BB	ARG461
W	GLY591
X	ARG461
X	SER475
X	SER566
X	ASN567
X	GLY591
Y	ARG461
Y	SER475
Y	SER566
Y	ASN567
BB	SER475
Y	GLY591
Z	ARG461
Z	SER475
Z	SER566
Z	ASN567
Z	GLY591
AA	ARG461
AA	SER475
AA	SER566
AA	ASN567
BB	SER566
AA	GLY591
CA	ARG461
CA	SER475
CA	SER566
CA	ASN567
CA	GLY591
DA	ARG461
DA	SER475
DA	SER566
DA	ASN567
BB	ASN567
DA	GLY591
EA	ARG461
EA	SER475
EA	SER566
EA	ASN567
EA	GLY591
FA	ARG461
FA	SER475
FA	SER566
FA	ASN567
B	SER475
BB	GLY591
FA	GLY591
GA	ARG461
GA	SER475
GA	SER566
GA	ASN567
GA	GLY591
HA	ARG461
HA	SER475
HA	SER566
HA	ASN567
CB	ARG461
HA	GLY591
IA	ARG461
IA	SER475
IA	SER566
IA	ASN567
IA	GLY591
JA	ARG461
JA	SER475
JA	SER566
JA	ASN567
CB	SER475
JA	GLY591
KA	ARG461
KA	SER475
KA	SER566
KA	ASN567
KA	GLY591
LA	ARG461
LA	SER475
LA	SER566
LA	ASN567
CB	SER566
LA	GLY591
MA	ARG461
MA	SER475
MA	SER566
MA	ASN567
MA	GLY591
NA	ARG461
NA	SER475
NA	SER566
NA	ASN567
CB	ASN567
NA	GLY591
OA	ARG461
OA	SER475
OA	SER566
OA	ASN567
OA	GLY591
PA	ARG461
PA	SER475
PA	SER566
PA	ASN567
CB	GLY591
PA	GLY591
QA	ARG461
QA	SER475
QA	SER566
QA	ASN567
QA	GLY591
RA	ARG461
RA	SER475
RA	SER566
RA	ASN567
DB	ARG461
RA	GLY591
SA	ARG461
SA	SER475
SA	SER566
SA	ASN567
SA	GLY591
TA	ARG461
TA	SER475
TA	SER566
TA	ASN567
DB	SER475
TA	GLY591
UA	ARG461
UA	SER475
UA	SER566
UA	ASN567
UA	GLY591
VA	ARG461
VA	SER475
VA	SER566
VA	ASN567
DB	SER566
VA	GLY591
WA	ARG461
WA	SER475
WA	SER566
WA	ASN567
WA	GLY591
XA	ARG461
XA	SER475
XA	SER566
XA	ASN567
DB	ASN567
XA	GLY591
YA	ARG461
YA	SER475
YA	SER566
YA	ASN567
YA	GLY591
ZA	ARG461
ZA	SER475
ZA	SER566
ZA	ASN567
B	SER566
DB	GLY591
ZA	GLY591
EB	ARG461
EB	SER475
EB	SER566
EB	ASN567
EB	GLY591
FB	ARG461
FB	SER475
FB	SER566
FB	ASN567
B	ASN567
FB	GLY591
GB	ARG461
GB	SER475
GB	SER566
GB	ASN567
GB	GLY591
HB	ARG461
HB	SER475
HB	SER566
HB	ASN567
B	GLY591
HB	GLY591
IB	ARG461
IB	SER475
IB	SER566
IB	ASN567
IB	GLY591
C	ARG461
C	SER475
C	SER566
C	ASN567
AB	ARG461
C	GLY591
D	ARG461
D	SER475
D	SER566
D	ASN567
D	GLY591
E	ARG461
E	SER475
E	SER566
E	ASN567
AB	SER475
E	GLY591
F	ARG461
F	SER475
F	SER566
F	ASN567
F	GLY591
G	ARG461
G	SER475
G	SER566
G	ASN567
AB	SER566
G	GLY591
H	ARG461
H	SER475
H	SER566
H	ASN567
H	GLY591
I	ARG461
I	SER475
I	SER566
I	ASN567
AB	ASN567
I	GLY591
J	ARG461
J	SER475
J	SER566
J	ASN567
J	GLY591
K	ARG461
K	SER475
K	SER566
K	ASN567

---

site_id	SWS_FT_FI3
Number of Residues	60
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
B	SER100
HB	SER100
IB	SER100
C	SER100
D	SER100
E	SER100
F	SER100
G	SER100
H	SER100
I	SER100
J	SER100
AB	SER100
K	SER100
L	SER100
M	SER100
N	SER100
O	SER100
P	SER100
Q	SER100
R	SER100
BA	SER100
S	SER100
A	SER100
T	SER100
V	SER100
W	SER100
X	SER100
Y	SER100
Z	SER100
AA	SER100
CA	SER100
DA	SER100
EA	SER100
BB	SER100
FA	SER100
GA	SER100
HA	SER100
IA	SER100
JA	SER100
KA	SER100
LA	SER100
MA	SER100
NA	SER100
OA	SER100
CB	SER100
PA	SER100
QA	SER100
RA	SER100
SA	SER100
TA	SER100
UA	SER100
VA	SER100
WA	SER100
XA	SER100
YA	SER100
DB	SER100
ZA	SER100
EB	SER100
FB	SER100
GB	SER100

---

site_id	SWS_FT_FI4
Number of Residues	60
Details	MOD_RES: N6-lipoyllysine => ECO:0000255|PROSITE-ProRule:PRU01066, ECO:0000269|PubMed:25525879

Chain	Residue	Details
B	LYS132
HB	LYS132
IB	LYS132
C	LYS132
D	LYS132
E	LYS132
F	LYS132
G	LYS132
H	LYS132
I	LYS132
J	LYS132
AB	LYS132
K	LYS132
L	LYS132
M	LYS132
N	LYS132
O	LYS132
P	LYS132
Q	LYS132
R	LYS132
BA	LYS132
S	LYS132
A	LYS132
T	LYS132
V	LYS132
W	LYS132
X	LYS132
Y	LYS132
Z	LYS132
AA	LYS132
CA	LYS132
DA	LYS132
EA	LYS132
BB	LYS132
FA	LYS132
GA	LYS132
HA	LYS132
IA	LYS132
JA	LYS132
KA	LYS132
LA	LYS132
MA	LYS132
NA	LYS132
OA	LYS132
CB	LYS132
PA	LYS132
QA	LYS132
RA	LYS132
SA	LYS132
TA	LYS132
UA	LYS132
VA	LYS132
WA	LYS132
XA	LYS132
YA	LYS132
DB	LYS132
ZA	LYS132
EB	LYS132
FB	LYS132
GB	LYS132

---

site_id	SWS_FT_FI5
Number of Residues	60
Details	MOD_RES: N6-lipoyllysine => ECO:0000255|PROSITE-ProRule:PRU01066, ECO:0000269|PubMed:15861126, ECO:0000269|PubMed:17532006, ECO:0000269|PubMed:17683942, ECO:0000269|PubMed:25525879, ECO:0007744|PDB:1Y8N, ECO:0007744|PDB:1Y8O, ECO:0007744|PDB:1Y8P, ECO:0007744|PDB:2PNR, ECO:0007744|PDB:2Q8I

Chain	Residue	Details
B	LYS259
HB	LYS259
IB	LYS259
C	LYS259
D	LYS259
E	LYS259
F	LYS259
G	LYS259
H	LYS259
I	LYS259
J	LYS259
AB	LYS259
K	LYS259
L	LYS259
M	LYS259
N	LYS259
O	LYS259
P	LYS259
Q	LYS259
R	LYS259
BA	LYS259
S	LYS259
A	LYS259
T	LYS259
V	LYS259
W	LYS259
X	LYS259
Y	LYS259
Z	LYS259
AA	LYS259
CA	LYS259
DA	LYS259
EA	LYS259
BB	LYS259
FA	LYS259
GA	LYS259
HA	LYS259
IA	LYS259
JA	LYS259
KA	LYS259
LA	LYS259
MA	LYS259
NA	LYS259
OA	LYS259
CB	LYS259
PA	LYS259
QA	LYS259
RA	LYS259
SA	LYS259
TA	LYS259
UA	LYS259
VA	LYS259
WA	LYS259
XA	LYS259
YA	LYS259
DB	LYS259
ZA	LYS259
EB	LYS259
FB	LYS259
GB	LYS259

---

site_id	SWS_FT_FI6
Number of Residues	60
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
B	LYS466
HB	LYS466
IB	LYS466
C	LYS466
D	LYS466
E	LYS466
F	LYS466
G	LYS466
H	LYS466
I	LYS466
J	LYS466
AB	LYS466
K	LYS466
L	LYS466
M	LYS466
N	LYS466
O	LYS466
P	LYS466
Q	LYS466
R	LYS466
BA	LYS466
S	LYS466
A	LYS466
T	LYS466
V	LYS466
W	LYS466
X	LYS466
Y	LYS466
Z	LYS466
AA	LYS466
CA	LYS466
DA	LYS466
EA	LYS466
BB	LYS466
FA	LYS466
GA	LYS466
HA	LYS466
IA	LYS466
JA	LYS466
KA	LYS466
LA	LYS466
MA	LYS466
NA	LYS466
OA	LYS466
CB	LYS466
PA	LYS466
QA	LYS466
RA	LYS466
SA	LYS466
TA	LYS466
UA	LYS466
VA	LYS466
WA	LYS466
XA	LYS466
YA	LYS466
DB	LYS466
ZA	LYS466
EB	LYS466
FB	LYS466
GB	LYS466

---

site_id	SWS_FT_FI7
Number of Residues	120
Details	MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q8BMF4

Chain	Residue	Details
B	LYS473
CB	LYS547
PA	LYS547
QA	LYS473
QA	LYS547
RA	LYS473
RA	LYS547
SA	LYS473
SA	LYS547
TA	LYS473
TA	LYS547
UA	LYS473
DB	LYS473
UA	LYS547
VA	LYS473
VA	LYS547
WA	LYS473
WA	LYS547
XA	LYS473
XA	LYS547
YA	LYS473
YA	LYS547
ZA	LYS473
DB	LYS547
ZA	LYS547
EB	LYS473
EB	LYS547
FB	LYS473
FB	LYS547
GB	LYS473
GB	LYS547
HB	LYS473
B	LYS547
HB	LYS547
IB	LYS473
IB	LYS547
C	LYS473
C	LYS547
D	LYS473
D	LYS547
E	LYS473
E	LYS547
F	LYS473
AB	LYS473
F	LYS547
G	LYS473
G	LYS547
H	LYS473
H	LYS547
I	LYS473
I	LYS547
J	LYS473
J	LYS547
K	LYS473
AB	LYS547
K	LYS547
L	LYS473
L	LYS547
M	LYS473
M	LYS547
N	LYS473
N	LYS547
O	LYS473
O	LYS547
P	LYS473
A	LYS473
P	LYS547
Q	LYS473
Q	LYS547
R	LYS473
R	LYS547
BA	LYS473
BA	LYS547
S	LYS473
S	LYS547
T	LYS473
A	LYS547
T	LYS547
V	LYS473
V	LYS547
W	LYS473
W	LYS547
X	LYS473
X	LYS547
Y	LYS473
Y	LYS547
Z	LYS473
BB	LYS473
Z	LYS547
AA	LYS473
AA	LYS547
CA	LYS473
CA	LYS547
DA	LYS473
DA	LYS547
EA	LYS473
EA	LYS547
FA	LYS473
BB	LYS547
FA	LYS547
GA	LYS473
GA	LYS547
HA	LYS473
HA	LYS547
IA	LYS473
IA	LYS547
JA	LYS473
JA	LYS547
KA	LYS473
CB	LYS473
KA	LYS547
LA	LYS473
LA	LYS547
MA	LYS473
MA	LYS547
NA	LYS473
NA	LYS547
OA	LYS473
OA	LYS547
PA	LYS473

---