8PIN

Crystal structure of Ser33

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004617	molecular_function	phosphoglycerate dehydrogenase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0006564	biological_process	L-serine biosynthetic process
A	0008652	biological_process	amino acid biosynthetic process
A	0009070	biological_process	serine family amino acid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0042802	molecular_function	identical protein binding
A	0051287	molecular_function	NAD binding
A	0061759	molecular_function	alpha-ketoglutarate reductase activity
B	0004617	molecular_function	phosphoglycerate dehydrogenase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0006564	biological_process	L-serine biosynthetic process
B	0008652	biological_process	amino acid biosynthetic process
B	0009070	biological_process	serine family amino acid biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0042802	molecular_function	identical protein binding
B	0051287	molecular_function	NAD binding
B	0061759	molecular_function	alpha-ketoglutarate reductase activity
C	0004617	molecular_function	phosphoglycerate dehydrogenase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0006564	biological_process	L-serine biosynthetic process
C	0008652	biological_process	amino acid biosynthetic process
C	0009070	biological_process	serine family amino acid biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0042802	molecular_function	identical protein binding
C	0051287	molecular_function	NAD binding
C	0061759	molecular_function	alpha-ketoglutarate reductase activity
D	0004617	molecular_function	phosphoglycerate dehydrogenase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0006564	biological_process	L-serine biosynthetic process
D	0008652	biological_process	amino acid biosynthetic process
D	0009070	biological_process	serine family amino acid biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0042802	molecular_function	identical protein binding
D	0051287	molecular_function	NAD binding
D	0061759	molecular_function	alpha-ketoglutarate reductase activity

Functional Information from PROSITE/UniProt

site_id	PS00065
Number of Residues	28
Details	D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. LGIIGyGHIGsqlsvlaeamglh.VLyYD

Chain	Residue	Details
A	LEU201-ASP228

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site_id	PS00670
Number of Residues	23
Details	D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. LLnkSDFVtLHvPatpeTekMlS

Chain	Residue	Details
A	LEU247-SER269

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site_id	PS00671
Number of Residues	17
Details	D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKdGaYVINaSRGtVVD

Chain	Residue	Details
A	MET276-ASP292

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000250

Chain	Residue	Details
A	ARG287
A	GLU316
C	ARG287
C	GLU316
D	ARG287
D	GLU316
B	ARG287
B	GLU316

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000250

Chain	Residue	Details
A	HIS347
C	HIS347
D	HIS347
B	HIS347

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0A9T0

Chain	Residue	Details
A	HIS208
C	HIS347
D	HIS208
D	ASP228
D	ALA285
D	ASP311
D	HIS347
B	HIS208
B	ASP228
B	ALA285
B	ASP311
A	ASP228
B	HIS347
A	ALA285
A	ASP311
A	HIS347
C	HIS208
C	ASP228
C	ALA285
C	ASP311

---