Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000837 | cellular_component | Doa10p ubiquitin ligase complex |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005635 | cellular_component | nuclear envelope |
| A | 0005637 | cellular_component | nuclear inner membrane |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016567 | biological_process | protein ubiquitination |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030970 | biological_process | retrograde protein transport, ER to cytosol |
| A | 0036503 | biological_process | ERAD pathway |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0061630 | molecular_function | ubiquitin protein ligase activity |
Functional Information from PROSITE/UniProt
| site_id | PS01159 |
| Number of Residues | 25 |
| Details | WW_DOMAIN_1 WW/rsp5/WWP domain signature. Wkfntilltl..YFtkrilesSSYVKP |
| Chain | Residue | Details |
| A | TRP781-PRO805 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 832 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-ALA131 | |
| A | ARG225-LYS468 | |
| A | LEU513-VAL626 | |
| A | GLY682-MET739 | |
| A | GLU798-TYR965 | |
| A | SER1041-ASN1113 | |
| A | LYS1190-LYS1213 | |
| A | GLN1292-SER1319 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 279 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU132-PHE152 | |
| A | LEU1020-LEU1040 | |
| A | LEU1114-LEU1134 | |
| A | LEU1169-LEU1189 | |
| A | GLN1214-LEU1234 | |
| A | PHE1271-ILE1291 | |
| A | LEU204-VAL224 | |
| A | LEU469-ILE489 | |
| A | LEU492-ILE512 | |
| A | PHE627-PHE647 | |
| A | LEU661-ILE681 | |
| A | PHE740-PHE760 | |
| A | ILE778-LEU797 | |
| A | MET966-ILE986 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 179 |
| Details | TOPO_DOM: Lumenal => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY153-SER203 | |
| A | SER490-TYR491 | |
| A | SER648-MET660 | |
| A | MET761-SER777 | |
| A | SER987-GLU1019 | |
| A | THR1135-SER1168 | |
| A | ARG1235-TYR1270 | |
| Chain | Residue | Details |
| A | ASP31-LYS100 | |
| Chain | Residue | Details |
| A | CYS39 | |
| A | CYS42 | |
| A | CYS56 | |
| A | CYS58 | |
| A | HIS66 | |
| A | CYS69 | |
| A | CYS90 | |
| A | CYS93 | |
