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8P3T

Homomeric GluA1 in tandem with TARP gamma-3, desensitized conformation 1

Functional Information from GO Data
ChainGOidnamespacecontents
A0001540molecular_functionamyloid-beta binding
A0001919biological_processregulation of receptor recycling
A0001965molecular_functionG-protein alpha-subunit binding
A0004970molecular_functionglutamate-gated receptor activity
A0004971molecular_functionAMPA glutamate receptor activity
A0005216molecular_functionmonoatomic ion channel activity
A0005515molecular_functionprotein binding
A0005768cellular_componentendosome
A0005769cellular_componentearly endosome
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005886cellular_componentplasma membrane
A0005911cellular_componentcell-cell junction
A0006811biological_processmonoatomic ion transport
A0007268biological_processchemical synaptic transmission
A0007416biological_processsynapse assembly
A0007616biological_processlong-term memory
A0008021cellular_componentsynaptic vesicle
A0008179molecular_functionadenylate cyclase binding
A0008328cellular_componentionotropic glutamate receptor complex
A0009410biological_processresponse to xenobiotic stimulus
A0009636biological_processresponse to toxic substance
A0009986cellular_componentcell surface
A0010226biological_processresponse to lithium ion
A0010628biological_processpositive regulation of gene expression
A0014069cellular_componentpostsynaptic density
A0014070biological_processresponse to organic cyclic compound
A0015276molecular_functionligand-gated monoatomic ion channel activity
A0016020cellular_componentmembrane
A0019228biological_processneuronal action potential
A0019722biological_processcalcium-mediated signaling
A0019865molecular_functionimmunoglobulin binding
A0019901molecular_functionprotein kinase binding
A0019904molecular_functionprotein domain specific binding
A0021510biological_processspinal cord development
A0021987biological_processcerebral cortex development
A0022849molecular_functionglutamate-gated calcium ion channel activity
A0022890molecular_functioninorganic cation transmembrane transporter activity
A0030165molecular_functionPDZ domain binding
A0030425cellular_componentdendrite
A0030672cellular_componentsynaptic vesicle membrane
A0031267molecular_functionsmall GTPase binding
A0031489molecular_functionmyosin V binding
A0031594cellular_componentneuromuscular junction
A0031623biological_processreceptor internalization
A0031681molecular_functionG-protein beta-subunit binding
A0031698molecular_functionbeta-2 adrenergic receptor binding
A0031901cellular_componentearly endosome membrane
A0032279cellular_componentasymmetric synapse
A0032281cellular_componentAMPA glutamate receptor complex
A0032355biological_processresponse to estradiol
A0032590cellular_componentdendrite membrane
A0032591cellular_componentdendritic spine membrane
A0032809cellular_componentneuronal cell body membrane
A0032991cellular_componentprotein-containing complex
A0034220biological_processmonoatomic ion transmembrane transport
A0035235biological_processionotropic glutamate receptor signaling pathway
A0035249biological_processsynaptic transmission, glutamatergic
A0035254molecular_functionglutamate receptor binding
A0036477cellular_componentsomatodendritic compartment
A0038023molecular_functionsignaling receptor activity
A0042220biological_processresponse to cocaine
A0042734cellular_componentpresynaptic membrane
A0042802molecular_functionidentical protein binding
A0042995cellular_componentcell projection
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043197cellular_componentdendritic spine
A0043198cellular_componentdendritic shaft
A0043226cellular_componentorganelle
A0043278biological_processresponse to morphine
A0043434biological_processresponse to peptide hormone
A0044297cellular_componentcell body
A0044308cellular_componentaxonal spine
A0044309cellular_componentneuron spine
A0045202cellular_componentsynapse
A0045211cellular_componentpostsynaptic membrane
A0045838biological_processpositive regulation of membrane potential
A0046685biological_processresponse to arsenic-containing substance
A0048167biological_processregulation of synaptic plasticity
A0048266biological_processbehavioral response to pain
A0048787cellular_componentpresynaptic active zone membrane
A0050804biological_processmodulation of chemical synaptic transmission
A0050806biological_processpositive regulation of synaptic transmission
A0051018molecular_functionprotein kinase A binding
A0051602biological_processresponse to electrical stimulus
A0055037cellular_componentrecycling endosome
A0055038cellular_componentrecycling endosome membrane
A0060076cellular_componentexcitatory synapse
A0060078biological_processregulation of postsynaptic membrane potential
A0060291biological_processlong-term synaptic potentiation
A0060292biological_processlong-term synaptic depression
A0060992biological_processresponse to fungicide
A0071230biological_processcellular response to amino acid stimulus
A0071242biological_processcellular response to ammonium ion
A0071359biological_processcellular response to dsRNA
A0071363biological_processcellular response to growth factor stimulus
A0071375biological_processcellular response to peptide hormone stimulus
A0071407biological_processcellular response to organic cyclic compound
A0071418biological_processcellular response to amine stimulus
A0097060cellular_componentsynaptic membrane
A0097110molecular_functionscaffold protein binding
A0098793cellular_componentpresynapse
A0098794cellular_componentpostsynapse
A0098839cellular_componentpostsynaptic density membrane
A0098978cellular_componentglutamatergic synapse
A0099092cellular_componentpostsynaptic density, intracellular component
A0099505biological_processregulation of presynaptic membrane potential
A0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
A0099544cellular_componentperisynaptic space
A0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
A0099583molecular_functionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
A1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
A1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
B0001540molecular_functionamyloid-beta binding
B0001919biological_processregulation of receptor recycling
B0001965molecular_functionG-protein alpha-subunit binding
B0004970molecular_functionglutamate-gated receptor activity
B0004971molecular_functionAMPA glutamate receptor activity
B0005216molecular_functionmonoatomic ion channel activity
B0005515molecular_functionprotein binding
B0005768cellular_componentendosome
B0005769cellular_componentearly endosome
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0005886cellular_componentplasma membrane
B0005911cellular_componentcell-cell junction
B0006811biological_processmonoatomic ion transport
B0007268biological_processchemical synaptic transmission
B0007416biological_processsynapse assembly
B0007616biological_processlong-term memory
B0008021cellular_componentsynaptic vesicle
B0008179molecular_functionadenylate cyclase binding
B0008328cellular_componentionotropic glutamate receptor complex
B0009410biological_processresponse to xenobiotic stimulus
B0009636biological_processresponse to toxic substance
B0009986cellular_componentcell surface
B0010226biological_processresponse to lithium ion
B0010628biological_processpositive regulation of gene expression
B0014069cellular_componentpostsynaptic density
B0014070biological_processresponse to organic cyclic compound
B0015276molecular_functionligand-gated monoatomic ion channel activity
B0016020cellular_componentmembrane
B0019228biological_processneuronal action potential
B0019722biological_processcalcium-mediated signaling
B0019865molecular_functionimmunoglobulin binding
B0019901molecular_functionprotein kinase binding
B0019904molecular_functionprotein domain specific binding
B0021510biological_processspinal cord development
B0021987biological_processcerebral cortex development
B0022849molecular_functionglutamate-gated calcium ion channel activity
B0022890molecular_functioninorganic cation transmembrane transporter activity
B0030165molecular_functionPDZ domain binding
B0030425cellular_componentdendrite
B0030672cellular_componentsynaptic vesicle membrane
B0031267molecular_functionsmall GTPase binding
B0031489molecular_functionmyosin V binding
B0031594cellular_componentneuromuscular junction
B0031623biological_processreceptor internalization
B0031681molecular_functionG-protein beta-subunit binding
B0031698molecular_functionbeta-2 adrenergic receptor binding
B0031901cellular_componentearly endosome membrane
B0032279cellular_componentasymmetric synapse
B0032281cellular_componentAMPA glutamate receptor complex
B0032355biological_processresponse to estradiol
B0032590cellular_componentdendrite membrane
B0032591cellular_componentdendritic spine membrane
B0032809cellular_componentneuronal cell body membrane
B0032991cellular_componentprotein-containing complex
B0034220biological_processmonoatomic ion transmembrane transport
B0035235biological_processionotropic glutamate receptor signaling pathway
B0035249biological_processsynaptic transmission, glutamatergic
B0035254molecular_functionglutamate receptor binding
B0036477cellular_componentsomatodendritic compartment
B0038023molecular_functionsignaling receptor activity
B0042220biological_processresponse to cocaine
B0042734cellular_componentpresynaptic membrane
B0042802molecular_functionidentical protein binding
B0042995cellular_componentcell projection
B0043005cellular_componentneuron projection
B0043025cellular_componentneuronal cell body
B0043197cellular_componentdendritic spine
B0043198cellular_componentdendritic shaft
B0043226cellular_componentorganelle
B0043278biological_processresponse to morphine
B0043434biological_processresponse to peptide hormone
B0044297cellular_componentcell body
B0044308cellular_componentaxonal spine
B0044309cellular_componentneuron spine
B0045202cellular_componentsynapse
B0045211cellular_componentpostsynaptic membrane
B0045838biological_processpositive regulation of membrane potential
B0046685biological_processresponse to arsenic-containing substance
B0048167biological_processregulation of synaptic plasticity
B0048266biological_processbehavioral response to pain
B0048787cellular_componentpresynaptic active zone membrane
B0050804biological_processmodulation of chemical synaptic transmission
B0050806biological_processpositive regulation of synaptic transmission
B0051018molecular_functionprotein kinase A binding
B0051602biological_processresponse to electrical stimulus
B0055037cellular_componentrecycling endosome
B0055038cellular_componentrecycling endosome membrane
B0060076cellular_componentexcitatory synapse
B0060078biological_processregulation of postsynaptic membrane potential
B0060291biological_processlong-term synaptic potentiation
B0060292biological_processlong-term synaptic depression
B0060992biological_processresponse to fungicide
B0071230biological_processcellular response to amino acid stimulus
B0071242biological_processcellular response to ammonium ion
B0071359biological_processcellular response to dsRNA
B0071363biological_processcellular response to growth factor stimulus
B0071375biological_processcellular response to peptide hormone stimulus
B0071407biological_processcellular response to organic cyclic compound
B0071418biological_processcellular response to amine stimulus
B0097060cellular_componentsynaptic membrane
B0097110molecular_functionscaffold protein binding
B0098793cellular_componentpresynapse
B0098794cellular_componentpostsynapse
B0098839cellular_componentpostsynaptic density membrane
B0098978cellular_componentglutamatergic synapse
B0099092cellular_componentpostsynaptic density, intracellular component
B0099505biological_processregulation of presynaptic membrane potential
B0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
B0099544cellular_componentperisynaptic space
B0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
B0099583molecular_functionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
B1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
C0001540molecular_functionamyloid-beta binding
C0001919biological_processregulation of receptor recycling
C0001965molecular_functionG-protein alpha-subunit binding
C0004970molecular_functionglutamate-gated receptor activity
C0004971molecular_functionAMPA glutamate receptor activity
C0005216molecular_functionmonoatomic ion channel activity
C0005515molecular_functionprotein binding
C0005768cellular_componentendosome
C0005769cellular_componentearly endosome
C0005783cellular_componentendoplasmic reticulum
C0005789cellular_componentendoplasmic reticulum membrane
C0005886cellular_componentplasma membrane
C0005911cellular_componentcell-cell junction
C0006811biological_processmonoatomic ion transport
C0007268biological_processchemical synaptic transmission
C0007416biological_processsynapse assembly
C0007616biological_processlong-term memory
C0008021cellular_componentsynaptic vesicle
C0008179molecular_functionadenylate cyclase binding
C0008328cellular_componentionotropic glutamate receptor complex
C0009410biological_processresponse to xenobiotic stimulus
C0009636biological_processresponse to toxic substance
C0009986cellular_componentcell surface
C0010226biological_processresponse to lithium ion
C0010628biological_processpositive regulation of gene expression
C0014069cellular_componentpostsynaptic density
C0014070biological_processresponse to organic cyclic compound
C0015276molecular_functionligand-gated monoatomic ion channel activity
C0016020cellular_componentmembrane
C0019228biological_processneuronal action potential
C0019722biological_processcalcium-mediated signaling
C0019865molecular_functionimmunoglobulin binding
C0019901molecular_functionprotein kinase binding
C0019904molecular_functionprotein domain specific binding
C0021510biological_processspinal cord development
C0021987biological_processcerebral cortex development
C0022849molecular_functionglutamate-gated calcium ion channel activity
C0022890molecular_functioninorganic cation transmembrane transporter activity
C0030165molecular_functionPDZ domain binding
C0030425cellular_componentdendrite
C0030672cellular_componentsynaptic vesicle membrane
C0031267molecular_functionsmall GTPase binding
C0031489molecular_functionmyosin V binding
C0031594cellular_componentneuromuscular junction
C0031623biological_processreceptor internalization
C0031681molecular_functionG-protein beta-subunit binding
C0031698molecular_functionbeta-2 adrenergic receptor binding
C0031901cellular_componentearly endosome membrane
C0032279cellular_componentasymmetric synapse
C0032281cellular_componentAMPA glutamate receptor complex
C0032355biological_processresponse to estradiol
C0032590cellular_componentdendrite membrane
C0032591cellular_componentdendritic spine membrane
C0032809cellular_componentneuronal cell body membrane
C0032991cellular_componentprotein-containing complex
C0034220biological_processmonoatomic ion transmembrane transport
C0035235biological_processionotropic glutamate receptor signaling pathway
C0035249biological_processsynaptic transmission, glutamatergic
C0035254molecular_functionglutamate receptor binding
C0036477cellular_componentsomatodendritic compartment
C0038023molecular_functionsignaling receptor activity
C0042220biological_processresponse to cocaine
C0042734cellular_componentpresynaptic membrane
C0042802molecular_functionidentical protein binding
C0042995cellular_componentcell projection
C0043005cellular_componentneuron projection
C0043025cellular_componentneuronal cell body
C0043197cellular_componentdendritic spine
C0043198cellular_componentdendritic shaft
C0043226cellular_componentorganelle
C0043278biological_processresponse to morphine
C0043434biological_processresponse to peptide hormone
C0044297cellular_componentcell body
C0044308cellular_componentaxonal spine
C0044309cellular_componentneuron spine
C0045202cellular_componentsynapse
C0045211cellular_componentpostsynaptic membrane
C0045838biological_processpositive regulation of membrane potential
C0046685biological_processresponse to arsenic-containing substance
C0048167biological_processregulation of synaptic plasticity
C0048266biological_processbehavioral response to pain
C0048787cellular_componentpresynaptic active zone membrane
C0050804biological_processmodulation of chemical synaptic transmission
C0050806biological_processpositive regulation of synaptic transmission
C0051018molecular_functionprotein kinase A binding
C0051602biological_processresponse to electrical stimulus
C0055037cellular_componentrecycling endosome
C0055038cellular_componentrecycling endosome membrane
C0060076cellular_componentexcitatory synapse
C0060078biological_processregulation of postsynaptic membrane potential
C0060291biological_processlong-term synaptic potentiation
C0060292biological_processlong-term synaptic depression
C0060992biological_processresponse to fungicide
C0071230biological_processcellular response to amino acid stimulus
C0071242biological_processcellular response to ammonium ion
C0071359biological_processcellular response to dsRNA
C0071363biological_processcellular response to growth factor stimulus
C0071375biological_processcellular response to peptide hormone stimulus
C0071407biological_processcellular response to organic cyclic compound
C0071418biological_processcellular response to amine stimulus
C0097060cellular_componentsynaptic membrane
C0097110molecular_functionscaffold protein binding
C0098793cellular_componentpresynapse
C0098794cellular_componentpostsynapse
C0098839cellular_componentpostsynaptic density membrane
C0098978cellular_componentglutamatergic synapse
C0099092cellular_componentpostsynaptic density, intracellular component
C0099505biological_processregulation of presynaptic membrane potential
C0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
C0099544cellular_componentperisynaptic space
C0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
C0099583molecular_functionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
C1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
D0001540molecular_functionamyloid-beta binding
D0001919biological_processregulation of receptor recycling
D0001965molecular_functionG-protein alpha-subunit binding
D0004970molecular_functionglutamate-gated receptor activity
D0004971molecular_functionAMPA glutamate receptor activity
D0005216molecular_functionmonoatomic ion channel activity
D0005515molecular_functionprotein binding
D0005768cellular_componentendosome
D0005769cellular_componentearly endosome
D0005783cellular_componentendoplasmic reticulum
D0005789cellular_componentendoplasmic reticulum membrane
D0005886cellular_componentplasma membrane
D0005911cellular_componentcell-cell junction
D0006811biological_processmonoatomic ion transport
D0007268biological_processchemical synaptic transmission
D0007416biological_processsynapse assembly
D0007616biological_processlong-term memory
D0008021cellular_componentsynaptic vesicle
D0008179molecular_functionadenylate cyclase binding
D0008328cellular_componentionotropic glutamate receptor complex
D0009410biological_processresponse to xenobiotic stimulus
D0009636biological_processresponse to toxic substance
D0009986cellular_componentcell surface
D0010226biological_processresponse to lithium ion
D0010628biological_processpositive regulation of gene expression
D0014069cellular_componentpostsynaptic density
D0014070biological_processresponse to organic cyclic compound
D0015276molecular_functionligand-gated monoatomic ion channel activity
D0016020cellular_componentmembrane
D0019228biological_processneuronal action potential
D0019722biological_processcalcium-mediated signaling
D0019865molecular_functionimmunoglobulin binding
D0019901molecular_functionprotein kinase binding
D0019904molecular_functionprotein domain specific binding
D0021510biological_processspinal cord development
D0021987biological_processcerebral cortex development
D0022849molecular_functionglutamate-gated calcium ion channel activity
D0022890molecular_functioninorganic cation transmembrane transporter activity
D0030165molecular_functionPDZ domain binding
D0030425cellular_componentdendrite
D0030672cellular_componentsynaptic vesicle membrane
D0031267molecular_functionsmall GTPase binding
D0031489molecular_functionmyosin V binding
D0031594cellular_componentneuromuscular junction
D0031623biological_processreceptor internalization
D0031681molecular_functionG-protein beta-subunit binding
D0031698molecular_functionbeta-2 adrenergic receptor binding
D0031901cellular_componentearly endosome membrane
D0032279cellular_componentasymmetric synapse
D0032281cellular_componentAMPA glutamate receptor complex
D0032355biological_processresponse to estradiol
D0032590cellular_componentdendrite membrane
D0032591cellular_componentdendritic spine membrane
D0032809cellular_componentneuronal cell body membrane
D0032991cellular_componentprotein-containing complex
D0034220biological_processmonoatomic ion transmembrane transport
D0035235biological_processionotropic glutamate receptor signaling pathway
D0035249biological_processsynaptic transmission, glutamatergic
D0035254molecular_functionglutamate receptor binding
D0036477cellular_componentsomatodendritic compartment
D0038023molecular_functionsignaling receptor activity
D0042220biological_processresponse to cocaine
D0042734cellular_componentpresynaptic membrane
D0042802molecular_functionidentical protein binding
D0042995cellular_componentcell projection
D0043005cellular_componentneuron projection
D0043025cellular_componentneuronal cell body
D0043197cellular_componentdendritic spine
D0043198cellular_componentdendritic shaft
D0043226cellular_componentorganelle
D0043278biological_processresponse to morphine
D0043434biological_processresponse to peptide hormone
D0044297cellular_componentcell body
D0044308cellular_componentaxonal spine
D0044309cellular_componentneuron spine
D0045202cellular_componentsynapse
D0045211cellular_componentpostsynaptic membrane
D0045838biological_processpositive regulation of membrane potential
D0046685biological_processresponse to arsenic-containing substance
D0048167biological_processregulation of synaptic plasticity
D0048266biological_processbehavioral response to pain
D0048787cellular_componentpresynaptic active zone membrane
D0050804biological_processmodulation of chemical synaptic transmission
D0050806biological_processpositive regulation of synaptic transmission
D0051018molecular_functionprotein kinase A binding
D0051602biological_processresponse to electrical stimulus
D0055037cellular_componentrecycling endosome
D0055038cellular_componentrecycling endosome membrane
D0060076cellular_componentexcitatory synapse
D0060078biological_processregulation of postsynaptic membrane potential
D0060291biological_processlong-term synaptic potentiation
D0060292biological_processlong-term synaptic depression
D0060992biological_processresponse to fungicide
D0071230biological_processcellular response to amino acid stimulus
D0071242biological_processcellular response to ammonium ion
D0071359biological_processcellular response to dsRNA
D0071363biological_processcellular response to growth factor stimulus
D0071375biological_processcellular response to peptide hormone stimulus
D0071407biological_processcellular response to organic cyclic compound
D0071418biological_processcellular response to amine stimulus
D0097060cellular_componentsynaptic membrane
D0097110molecular_functionscaffold protein binding
D0098793cellular_componentpresynapse
D0098794cellular_componentpostsynapse
D0098839cellular_componentpostsynaptic density membrane
D0098978cellular_componentglutamatergic synapse
D0099092cellular_componentpostsynaptic density, intracellular component
D0099505biological_processregulation of presynaptic membrane potential
D0099507molecular_functionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
D0099544cellular_componentperisynaptic space
D0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
D0099583molecular_functionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration
D1904315molecular_functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D1990416biological_processcellular response to brain-derived neurotrophic factor stimulus
E0005245molecular_functionvoltage-gated calcium channel activity
E0005262molecular_functioncalcium channel activity
E0006605biological_processprotein targeting
E0006816biological_processcalcium ion transport
E0008104biological_processprotein localization
E0014069cellular_componentpostsynaptic density
E0016020cellular_componentmembrane
E0016247molecular_functionchannel regulator activity
E0019226biological_processtransmission of nerve impulse
E0030165molecular_functionPDZ domain binding
E0030425cellular_componentdendrite
E0032281cellular_componentAMPA glutamate receptor complex
E0034702cellular_componentmonoatomic ion channel complex
E0035255molecular_functionionotropic glutamate receptor binding
E0036477cellular_componentsomatodendritic compartment
E0051968biological_processpositive regulation of synaptic transmission, glutamatergic
E0060076cellular_componentexcitatory synapse
E0070588biological_processcalcium ion transmembrane transport
E0098685cellular_componentSchaffer collateral - CA1 synapse
E0098839cellular_componentpostsynaptic density membrane
E0098943biological_processneurotransmitter receptor transport, postsynaptic endosome to lysosome
E0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
E0098978cellular_componentglutamatergic synapse
E0099590biological_processneurotransmitter receptor internalization
E0099645biological_processneurotransmitter receptor localization to postsynaptic specialization membrane
E2000311biological_processregulation of AMPA receptor activity
F0005245molecular_functionvoltage-gated calcium channel activity
F0005262molecular_functioncalcium channel activity
F0006605biological_processprotein targeting
F0006816biological_processcalcium ion transport
F0008104biological_processprotein localization
F0014069cellular_componentpostsynaptic density
F0016020cellular_componentmembrane
F0016247molecular_functionchannel regulator activity
F0019226biological_processtransmission of nerve impulse
F0030165molecular_functionPDZ domain binding
F0030425cellular_componentdendrite
F0032281cellular_componentAMPA glutamate receptor complex
F0034702cellular_componentmonoatomic ion channel complex
F0035255molecular_functionionotropic glutamate receptor binding
F0036477cellular_componentsomatodendritic compartment
F0051968biological_processpositive regulation of synaptic transmission, glutamatergic
F0060076cellular_componentexcitatory synapse
F0070588biological_processcalcium ion transmembrane transport
F0098685cellular_componentSchaffer collateral - CA1 synapse
F0098839cellular_componentpostsynaptic density membrane
F0098943biological_processneurotransmitter receptor transport, postsynaptic endosome to lysosome
F0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
F0098978cellular_componentglutamatergic synapse
F0099590biological_processneurotransmitter receptor internalization
F0099645biological_processneurotransmitter receptor localization to postsynaptic specialization membrane
F2000311biological_processregulation of AMPA receptor activity
G0005245molecular_functionvoltage-gated calcium channel activity
G0005262molecular_functioncalcium channel activity
G0006605biological_processprotein targeting
G0006816biological_processcalcium ion transport
G0008104biological_processprotein localization
G0014069cellular_componentpostsynaptic density
G0016020cellular_componentmembrane
G0016247molecular_functionchannel regulator activity
G0019226biological_processtransmission of nerve impulse
G0030165molecular_functionPDZ domain binding
G0030425cellular_componentdendrite
G0032281cellular_componentAMPA glutamate receptor complex
G0034702cellular_componentmonoatomic ion channel complex
G0035255molecular_functionionotropic glutamate receptor binding
G0036477cellular_componentsomatodendritic compartment
G0051968biological_processpositive regulation of synaptic transmission, glutamatergic
G0060076cellular_componentexcitatory synapse
G0070588biological_processcalcium ion transmembrane transport
G0098685cellular_componentSchaffer collateral - CA1 synapse
G0098839cellular_componentpostsynaptic density membrane
G0098943biological_processneurotransmitter receptor transport, postsynaptic endosome to lysosome
G0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
G0098978cellular_componentglutamatergic synapse
G0099590biological_processneurotransmitter receptor internalization
G0099645biological_processneurotransmitter receptor localization to postsynaptic specialization membrane
G2000311biological_processregulation of AMPA receptor activity
H0005245molecular_functionvoltage-gated calcium channel activity
H0005262molecular_functioncalcium channel activity
H0006605biological_processprotein targeting
H0006816biological_processcalcium ion transport
H0008104biological_processprotein localization
H0014069cellular_componentpostsynaptic density
H0016020cellular_componentmembrane
H0016247molecular_functionchannel regulator activity
H0019226biological_processtransmission of nerve impulse
H0030165molecular_functionPDZ domain binding
H0030425cellular_componentdendrite
H0032281cellular_componentAMPA glutamate receptor complex
H0034702cellular_componentmonoatomic ion channel complex
H0035255molecular_functionionotropic glutamate receptor binding
H0036477cellular_componentsomatodendritic compartment
H0051968biological_processpositive regulation of synaptic transmission, glutamatergic
H0060076cellular_componentexcitatory synapse
H0070588biological_processcalcium ion transmembrane transport
H0098685cellular_componentSchaffer collateral - CA1 synapse
H0098839cellular_componentpostsynaptic density membrane
H0098943biological_processneurotransmitter receptor transport, postsynaptic endosome to lysosome
H0098970biological_processpostsynaptic neurotransmitter receptor diffusion trapping
H0098978cellular_componentglutamatergic synapse
H0099590biological_processneurotransmitter receptor internalization
H0099645biological_processneurotransmitter receptor localization to postsynaptic specialization membrane
H2000311biological_processregulation of AMPA receptor activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues320
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
EILE8-VAL28
ESER104-ALA124
EILE135-VAL155
EPHE181-ILE201
FILE8-VAL28
FSER104-ALA124
FILE135-VAL155
FPHE181-ILE201
GILE8-VAL28
GSER104-ALA124
GILE135-VAL155
GPHE181-ILE201
HILE8-VAL28
HSER104-ALA124
HILE135-VAL155
HPHE181-ILE201

site_idSWS_FT_FI2
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:22673903
ChainResidueDetails
ESER248
FSER248
GSER248
HSER248
CTYR519-VAL539
CLEU592-TYR612
DTYR519-VAL539
DLEU592-TYR612

site_idSWS_FT_FI3
Number of Residues444
DetailsTOPO_DOM: Cytoplasmic => ECO:0000250
ChainResidueDetails
ASER540-GLU566
AASP586-SER591
AGLU809-LEU889
BASP586-SER591
BGLU809-LEU889
CSER540-GLU566
CGLU809-LEU889
DSER540-GLU566
BSER540-GLU566
CASP586-SER591
DASP586-SER591
DGLU809-LEU889

site_idSWS_FT_FI4
Number of Residues60
DetailsINTRAMEM: Helical; Pore-forming => ECO:0000250
ChainResidueDetails
APHE567-GLN582
BPHE567-GLN582
CPHE567-GLN582
DPHE567-GLN582

site_idSWS_FT_FI5
Number of Residues8
DetailsINTRAMEM: INTRAMEM => ECO:0000250
ChainResidueDetails
AGLN583-CYS585
BGLN583-CYS585
DGLN583-CYS585
CGLN583-CYS585

site_idSWS_FT_FI6
Number of Residues80
DetailsTRANSMEM: Helical; Name=M4 => ECO:0000250
ChainResidueDetails
AVAL788-ILE808
BVAL788-ILE808
CVAL788-ILE808
DVAL788-ILE808

site_idSWS_FT_FI7
Number of Residues20
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
ATYR446
APRO474
AARG481
ASER650
AGLU701
BTYR446
BPRO474
BSER650
BGLU701
CTYR446
CPRO474
CARG481
CSER650
CGLU701
BARG481
DTYR446
DPRO474
DARG481
DSER650
DGLU701

site_idSWS_FT_FI8
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:7877986
ChainResidueDetails
ASER627
BSER627
CSER627
DSER627

site_idSWS_FT_FI9
Number of Residues4
DetailsMOD_RES: Phosphoserine; by PKC => ECO:0000269|PubMed:8848293
ChainResidueDetails
ASER692
BSER692
CSER692
DSER692

site_idSWS_FT_FI10
Number of Residues4
DetailsMOD_RES: Phosphoserine; by PKC, PKA and CAMK2 => ECO:0000269|PubMed:7877986, ECO:0000269|PubMed:9405465
ChainResidueDetails
ASER831
BSER831
CSER831
DSER831

site_idSWS_FT_FI11
Number of Residues4
DetailsMOD_RES: Phosphoserine; by PKC, PKA and PKG/PRKG2 => ECO:0000269|PubMed:18031684, ECO:0000269|PubMed:9405465
ChainResidueDetails
ASER845
BSER845
CSER845
DSER845

site_idSWS_FT_FI12
Number of Residues8
DetailsLIPID: S-palmitoyl cysteine => ECO:0000250
ChainResidueDetails
ACYS585
ACYS811
BCYS585
BCYS811
CCYS585
CCYS811
DCYS585
DCYS811

site_idSWS_FT_FI13
Number of Residues16
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:21639859
ChainResidueDetails
AASN45
AASN231
AASN239
AASN345
BASN45
BASN231
BASN239
BASN345
CASN345
DASN45
DASN231
DASN239
DASN345
CASN45
CASN231
CASN239

site_idSWS_FT_FI14
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN383
AASN388
BASN383
BASN388
CASN383
CASN388
DASN383
DASN388

219869

PDB entries from 2024-05-15

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