8P1K

Structure of hantaan orthohantavirus (HTNV) polymerase - Apo core endonuclease

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0001172	biological_process	RNA-templated transcription
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0006351	biological_process	DNA-templated transcription
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0016787	molecular_function	hydrolase activity
A	0019079	biological_process	viral genome replication
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0039689	biological_process	negative stranded viral RNA replication
A	0039694	biological_process	viral RNA genome replication
A	0039696	biological_process	RNA-templated viral transcription
A	0044220	cellular_component	host cell perinuclear region of cytoplasm
A	0046872	molecular_function	metal ion binding
A	0075526	biological_process	cap snatching

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	186
Details	Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"For endonuclease activity","evidences":[{"source":"PubMed","id":"27304209","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27304209","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"I0DF35","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---