8OYT
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '3 up' RBD conformation
This is a non-PDB format compatible entry.
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32142651, ECO:0000269|PubMed:32362314, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | SER682 | |
| B | SER682 | |
| C | SER682 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host TMPRSS2 or CTSL => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32703818, ECO:0000269|PubMed:34159616 |
| Chain | Residue | Details |
| A | ARG812 | |
| B | ARG812 | |
| C | ARG812 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN17 | |
| A | ASN1155 | |
| A | ASN1170 | |
| B | ASN17 | |
| B | ASN1155 | |
| B | ASN1170 | |
| C | ASN17 | |
| C | ASN1155 | |
| C | ASN1170 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN61 | |
| B | ASN1071 | |
| C | ASN61 | |
| C | ASN120 | |
| C | ASN714 | |
| C | ASN798 | |
| C | ASN1071 | |
| A | ASN120 | |
| A | ASN714 | |
| A | ASN798 | |
| A | ASN1071 | |
| B | ASN61 | |
| B | ASN120 | |
| B | ASN714 | |
| B | ASN798 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN72 | |
| A | LYS145 | |
| A | ASN1191 | |
| B | ASN72 | |
| B | LYS145 | |
| B | ASN1191 | |
| C | ASN72 | |
| C | LYS145 | |
| C | ASN1191 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 21 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | CYS161 | |
| B | ASN328 | |
| B | ASN340 | |
| B | ASN613 | |
| B | ASN654 | |
| B | ASN1095 | |
| C | CYS161 | |
| C | ASN279 | |
| C | ASN328 | |
| C | ASN340 | |
| C | ASN613 | |
| A | ASN279 | |
| C | ASN654 | |
| C | ASN1095 | |
| A | ASN328 | |
| A | ASN340 | |
| A | ASN613 | |
| A | ASN654 | |
| A | ASN1095 | |
| B | CYS161 | |
| B | ASN279 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32363391, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN231 | |
| A | ASN706 | |
| B | ASN231 | |
| B | ASN706 | |
| C | ASN231 | |
| C | ASN706 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (GalNAc) threonine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | THR320 | |
| B | THR320 | |
| C | THR320 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | CARBOHYD: O-linked (HexNAc...) serine; by host => ECO:0000269|PubMed:32363391 |
| Chain | Residue | Details |
| A | SER322 | |
| B | SER322 | |
| C | SER322 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (hybrid) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN600 | |
| B | ASN600 | |
| C | ASN600 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 6 |
| Details | CARBOHYD: O-linked (GlcNAc...) threonine; by host GALNT1 => ECO:0000269|PubMed:34732583 |
| Chain | Residue | Details |
| A | THR673 | |
| A | THR675 | |
| B | THR673 | |
| B | THR675 | |
| C | THR673 | |
| C | THR675 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04099, ECO:0000269|PubMed:32155444, ECO:0000269|PubMed:32366695, ECO:0000269|PubMed:32979942 |
| Chain | Residue | Details |
| A | ASN1131 | |
| B | ASN1131 | |
| C | ASN1131 |
