8OVX

Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus

Functional Information from GO Data

Chain	GOid	namespace	contents
O	0000775	cellular_component	chromosome, centromeric region
O	0000776	cellular_component	kinetochore
O	0000817	cellular_component	COMA complex
O	0003674	molecular_function	molecular_function
O	0005634	cellular_component	nucleus
O	0005694	cellular_component	chromosome
O	0008608	biological_process	attachment of spindle microtubules to kinetochore
O	0034087	biological_process	establishment of mitotic sister chromatid cohesion
O	0034508	biological_process	centromere complex assembly
O	0051301	biological_process	cell division
O	0051321	biological_process	meiotic cell cycle
O	0071459	biological_process	protein localization to chromosome, centromeric region
O	1905262	biological_process	negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination
P	0000775	cellular_component	chromosome, centromeric region
P	0000776	cellular_component	kinetochore
P	0000817	cellular_component	COMA complex
P	0003674	molecular_function	molecular_function
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005694	cellular_component	chromosome
P	0007059	biological_process	chromosome segregation
P	0007094	biological_process	mitotic spindle assembly checkpoint signaling
P	0008608	biological_process	attachment of spindle microtubules to kinetochore
P	0034087	biological_process	establishment of mitotic sister chromatid cohesion
P	0051301	biological_process	cell division
P	0051321	biological_process	meiotic cell cycle
P	0071459	biological_process	protein localization to chromosome, centromeric region
Q	0000775	cellular_component	chromosome, centromeric region
Q	0000776	cellular_component	kinetochore
Q	0000817	cellular_component	COMA complex
Q	0003674	molecular_function	molecular_function
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005694	cellular_component	chromosome
Q	0008608	biological_process	attachment of spindle microtubules to kinetochore
Q	0051301	biological_process	cell division
Q	0051321	biological_process	meiotic cell cycle
U	0000775	cellular_component	chromosome, centromeric region
U	0000776	cellular_component	kinetochore
U	0000817	cellular_component	COMA complex
U	0003674	molecular_function	molecular_function
U	0005634	cellular_component	nucleus
U	0005694	cellular_component	chromosome
U	0005737	cellular_component	cytoplasm
U	0005816	cellular_component	spindle pole body
U	0008608	biological_process	attachment of spindle microtubules to kinetochore
U	0034501	biological_process	protein localization to kinetochore
U	0051301	biological_process	cell division
U	0051321	biological_process	meiotic cell cycle
Y	0000775	cellular_component	chromosome, centromeric region
Y	0000776	cellular_component	kinetochore
Y	0003674	molecular_function	molecular_function
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005694	cellular_component	chromosome
Y	0008150	biological_process	biological_process
Y	0008608	biological_process	attachment of spindle microtubules to kinetochore
Y	0051301	biological_process	cell division
Y	0051321	biological_process	meiotic cell cycle
Z	0000775	cellular_component	chromosome, centromeric region
Z	0000776	cellular_component	kinetochore
Z	0003674	molecular_function	molecular_function
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005694	cellular_component	chromosome
Z	0007059	biological_process	chromosome segregation
Z	0008608	biological_process	attachment of spindle microtubules to kinetochore
Z	0031511	cellular_component	Mis6-Sim4 complex
Z	0051301	biological_process	cell division
Z	0051321	biological_process	meiotic cell cycle

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
Y	SER222

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198

Chain	Residue	Details
U	SER45

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198

Chain	Residue	Details
U	SER53

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site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956

Chain	Residue	Details
U	SER59
U	SER101

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