Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

8OPQ

Structure of Human Solute Carrier 26 family member A6 (SLC26A6) anion transporter in an inward-facing state

Functional Information from GO Data
ChainGOidnamespacecontents
A0005254molecular_functionchloride channel activity
A0005452molecular_functionsolute:inorganic anion antiporter activity
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0006821biological_processchloride transport
A0008271molecular_functionsecondary active sulfate transmembrane transporter activity
A0012506cellular_componentvesicle membrane
A0015106molecular_functionbicarbonate transmembrane transporter activity
A0015108molecular_functionchloride transmembrane transporter activity
A0015116molecular_functionsulfate transmembrane transporter activity
A0015297molecular_functionantiporter activity
A0015499molecular_functionformate transmembrane transporter activity
A0015562molecular_functionefflux transmembrane transporter activity
A0015701biological_processbicarbonate transport
A0015724biological_processformate transport
A0015797biological_processmannitol transmembrane transport
A0016020cellular_componentmembrane
A0016323cellular_componentbasolateral plasma membrane
A0016324cellular_componentapical plasma membrane
A0016740molecular_functiontransferase activity
A0019531molecular_functionoxalate transmembrane transporter activity
A0019532biological_processoxalate transport
A0030165molecular_functionPDZ domain binding
A0030321biological_processtransepithelial chloride transport
A0030659cellular_componentcytoplasmic vesicle membrane
A0031410cellular_componentcytoplasmic vesicle
A0031526cellular_componentbrush border membrane
A0031982cellular_componentvesicle
A0034220biological_processmonoatomic ion transmembrane transport
A0034707cellular_componentchloride channel complex
A0042045biological_processepithelial fluid transport
A0044849biological_processestrous cycle
A0046724biological_processoxalic acid secretion
A0048240biological_processsperm capacitation
A0050892biological_processintestinal absorption
A0051453biological_processregulation of intracellular pH
A0051454biological_processintracellular pH elevation
A0055085biological_processtransmembrane transport
A0070633biological_processtransepithelial transport
A0071320biological_processcellular response to cAMP
A0071332biological_processcellular response to fructose stimulus
A0071346biological_processcellular response to type II interferon
A0097225cellular_componentsperm midpiece
A0140900molecular_functionchloride:bicarbonate antiporter activity
A1902358biological_processsulfate transmembrane transport
A1902476biological_processchloride transmembrane transport
A2001150biological_processpositive regulation of dipeptide transmembrane transport
B0005254molecular_functionchloride channel activity
B0005452molecular_functionsolute:inorganic anion antiporter activity
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0006821biological_processchloride transport
B0008271molecular_functionsecondary active sulfate transmembrane transporter activity
B0012506cellular_componentvesicle membrane
B0015106molecular_functionbicarbonate transmembrane transporter activity
B0015108molecular_functionchloride transmembrane transporter activity
B0015116molecular_functionsulfate transmembrane transporter activity
B0015297molecular_functionantiporter activity
B0015499molecular_functionformate transmembrane transporter activity
B0015562molecular_functionefflux transmembrane transporter activity
B0015701biological_processbicarbonate transport
B0015724biological_processformate transport
B0015797biological_processmannitol transmembrane transport
B0016020cellular_componentmembrane
B0016323cellular_componentbasolateral plasma membrane
B0016324cellular_componentapical plasma membrane
B0016740molecular_functiontransferase activity
B0019531molecular_functionoxalate transmembrane transporter activity
B0019532biological_processoxalate transport
B0030165molecular_functionPDZ domain binding
B0030321biological_processtransepithelial chloride transport
B0030659cellular_componentcytoplasmic vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0031526cellular_componentbrush border membrane
B0031982cellular_componentvesicle
B0034220biological_processmonoatomic ion transmembrane transport
B0034707cellular_componentchloride channel complex
B0042045biological_processepithelial fluid transport
B0044849biological_processestrous cycle
B0046724biological_processoxalic acid secretion
B0048240biological_processsperm capacitation
B0050892biological_processintestinal absorption
B0051453biological_processregulation of intracellular pH
B0051454biological_processintracellular pH elevation
B0055085biological_processtransmembrane transport
B0070633biological_processtransepithelial transport
B0071320biological_processcellular response to cAMP
B0071332biological_processcellular response to fructose stimulus
B0071346biological_processcellular response to type II interferon
B0097225cellular_componentsperm midpiece
B0140900molecular_functionchloride:bicarbonate antiporter activity
B1902358biological_processsulfate transmembrane transport
B1902476biological_processchloride transmembrane transport
B2001150biological_processpositive regulation of dipeptide transmembrane transport
Functional Information from PROSITE/UniProt
site_idPS01130
Number of Residues22
DetailsSLC26A SLC26A transporters signature. PvFGLYSSfypvFIYflfGTSR
ChainResidueDetails
APRO119-ARG140

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues320
DetailsTransmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues226
DetailsTopological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues204
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues4
DetailsGlycosylation: {"description":"N-linked (GlcNAc) asparagine","evidences":[{"source":"PubMed","id":"27681177","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues4
DetailsModified residue: {"description":"Phosphoserine; by PKC","evidences":[{"source":"PubMed","id":"15990874","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

248335

PDB entries from 2026-01-28

PDB statisticsPDBj update infoContact PDBjnumon