8OP2

Stacks of nucleocapsid rings of the N1-370 mutant of the human Respiratory Syncytial Virus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0019013	cellular_component	viral nucleocapsid
A	0019028	cellular_component	viral capsid
A	0019029	cellular_component	helical viral capsid
A	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
A	0030430	cellular_component	host cell cytoplasm
A	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
A	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
A	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
A	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
A	0044423	cellular_component	virion component
A	0052031	biological_process	symbiont-mediated perturbation of host defense response
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response
A	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
A	1990904	cellular_component	ribonucleoprotein complex
B	0003723	molecular_function	RNA binding
B	0005515	molecular_function	protein binding
B	0019013	cellular_component	viral nucleocapsid
B	0019028	cellular_component	viral capsid
B	0019029	cellular_component	helical viral capsid
B	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
B	0030430	cellular_component	host cell cytoplasm
B	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
B	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
B	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
B	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
B	0044423	cellular_component	virion component
B	0052031	biological_process	symbiont-mediated perturbation of host defense response
B	0052170	biological_process	symbiont-mediated suppression of host innate immune response
B	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
B	1990904	cellular_component	ribonucleoprotein complex
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0019013	cellular_component	viral nucleocapsid
D	0019028	cellular_component	viral capsid
D	0019029	cellular_component	helical viral capsid
D	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
D	0030430	cellular_component	host cell cytoplasm
D	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
D	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
D	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
D	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
D	0044423	cellular_component	virion component
D	0052031	biological_process	symbiont-mediated perturbation of host defense response
D	0052170	biological_process	symbiont-mediated suppression of host innate immune response
D	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
D	1990904	cellular_component	ribonucleoprotein complex
E	0003723	molecular_function	RNA binding
E	0005515	molecular_function	protein binding
E	0019013	cellular_component	viral nucleocapsid
E	0019028	cellular_component	viral capsid
E	0019029	cellular_component	helical viral capsid
E	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
E	0030430	cellular_component	host cell cytoplasm
E	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
E	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
E	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
E	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
E	0044423	cellular_component	virion component
E	0052031	biological_process	symbiont-mediated perturbation of host defense response
E	0052170	biological_process	symbiont-mediated suppression of host innate immune response
E	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
E	1990904	cellular_component	ribonucleoprotein complex
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0019013	cellular_component	viral nucleocapsid
G	0019028	cellular_component	viral capsid
G	0019029	cellular_component	helical viral capsid
G	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
G	0030430	cellular_component	host cell cytoplasm
G	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
G	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
G	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
G	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
G	0044423	cellular_component	virion component
G	0052031	biological_process	symbiont-mediated perturbation of host defense response
G	0052170	biological_process	symbiont-mediated suppression of host innate immune response
G	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
G	1990904	cellular_component	ribonucleoprotein complex
H	0003723	molecular_function	RNA binding
H	0005515	molecular_function	protein binding
H	0019013	cellular_component	viral nucleocapsid
H	0019028	cellular_component	viral capsid
H	0019029	cellular_component	helical viral capsid
H	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
H	0030430	cellular_component	host cell cytoplasm
H	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
H	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
H	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
H	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
H	0044423	cellular_component	virion component
H	0052031	biological_process	symbiont-mediated perturbation of host defense response
H	0052170	biological_process	symbiont-mediated suppression of host innate immune response
H	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
H	1990904	cellular_component	ribonucleoprotein complex
J	0003723	molecular_function	RNA binding
J	0005515	molecular_function	protein binding
J	0019013	cellular_component	viral nucleocapsid
J	0019028	cellular_component	viral capsid
J	0019029	cellular_component	helical viral capsid
J	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
J	0030430	cellular_component	host cell cytoplasm
J	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
J	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
J	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
J	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
J	0044423	cellular_component	virion component
J	0052031	biological_process	symbiont-mediated perturbation of host defense response
J	0052170	biological_process	symbiont-mediated suppression of host innate immune response
J	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
J	1990904	cellular_component	ribonucleoprotein complex
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0019013	cellular_component	viral nucleocapsid
K	0019028	cellular_component	viral capsid
K	0019029	cellular_component	helical viral capsid
K	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
K	0030430	cellular_component	host cell cytoplasm
K	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
K	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
K	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
K	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
K	0044423	cellular_component	virion component
K	0052031	biological_process	symbiont-mediated perturbation of host defense response
K	0052170	biological_process	symbiont-mediated suppression of host innate immune response
K	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
K	1990904	cellular_component	ribonucleoprotein complex
M	0003723	molecular_function	RNA binding
M	0005515	molecular_function	protein binding
M	0019013	cellular_component	viral nucleocapsid
M	0019028	cellular_component	viral capsid
M	0019029	cellular_component	helical viral capsid
M	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
M	0030430	cellular_component	host cell cytoplasm
M	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
M	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
M	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
M	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
M	0044423	cellular_component	virion component
M	0052031	biological_process	symbiont-mediated perturbation of host defense response
M	0052170	biological_process	symbiont-mediated suppression of host innate immune response
M	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
M	1990904	cellular_component	ribonucleoprotein complex
N	0003723	molecular_function	RNA binding
N	0005515	molecular_function	protein binding
N	0019013	cellular_component	viral nucleocapsid
N	0019028	cellular_component	viral capsid
N	0019029	cellular_component	helical viral capsid
N	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
N	0030430	cellular_component	host cell cytoplasm
N	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
N	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
N	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
N	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
N	0044423	cellular_component	virion component
N	0052031	biological_process	symbiont-mediated perturbation of host defense response
N	0052170	biological_process	symbiont-mediated suppression of host innate immune response
N	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
N	1990904	cellular_component	ribonucleoprotein complex
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0019013	cellular_component	viral nucleocapsid
P	0019028	cellular_component	viral capsid
P	0019029	cellular_component	helical viral capsid
P	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
P	0030430	cellular_component	host cell cytoplasm
P	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
P	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
P	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
P	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
P	0044423	cellular_component	virion component
P	0052031	biological_process	symbiont-mediated perturbation of host defense response
P	0052170	biological_process	symbiont-mediated suppression of host innate immune response
P	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
P	1990904	cellular_component	ribonucleoprotein complex
Q	0003723	molecular_function	RNA binding
Q	0005515	molecular_function	protein binding
Q	0019013	cellular_component	viral nucleocapsid
Q	0019028	cellular_component	viral capsid
Q	0019029	cellular_component	helical viral capsid
Q	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
Q	0030430	cellular_component	host cell cytoplasm
Q	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
Q	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
Q	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
Q	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
Q	0044423	cellular_component	virion component
Q	0052031	biological_process	symbiont-mediated perturbation of host defense response
Q	0052170	biological_process	symbiont-mediated suppression of host innate immune response
Q	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
Q	1990904	cellular_component	ribonucleoprotein complex
S	0003723	molecular_function	RNA binding
S	0005515	molecular_function	protein binding
S	0019013	cellular_component	viral nucleocapsid
S	0019028	cellular_component	viral capsid
S	0019029	cellular_component	helical viral capsid
S	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
S	0030430	cellular_component	host cell cytoplasm
S	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
S	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
S	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
S	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
S	0044423	cellular_component	virion component
S	0052031	biological_process	symbiont-mediated perturbation of host defense response
S	0052170	biological_process	symbiont-mediated suppression of host innate immune response
S	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
S	1990904	cellular_component	ribonucleoprotein complex
T	0003723	molecular_function	RNA binding
T	0005515	molecular_function	protein binding
T	0019013	cellular_component	viral nucleocapsid
T	0019028	cellular_component	viral capsid
T	0019029	cellular_component	helical viral capsid
T	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
T	0030430	cellular_component	host cell cytoplasm
T	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
T	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
T	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
T	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
T	0044423	cellular_component	virion component
T	0052031	biological_process	symbiont-mediated perturbation of host defense response
T	0052170	biological_process	symbiont-mediated suppression of host innate immune response
T	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
T	1990904	cellular_component	ribonucleoprotein complex
c	0003723	molecular_function	RNA binding
c	0005515	molecular_function	protein binding
c	0019013	cellular_component	viral nucleocapsid
c	0019028	cellular_component	viral capsid
c	0019029	cellular_component	helical viral capsid
c	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
c	0030430	cellular_component	host cell cytoplasm
c	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
c	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
c	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
c	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
c	0044423	cellular_component	virion component
c	0052031	biological_process	symbiont-mediated perturbation of host defense response
c	0052170	biological_process	symbiont-mediated suppression of host innate immune response
c	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
c	1990904	cellular_component	ribonucleoprotein complex
d	0003723	molecular_function	RNA binding
d	0005515	molecular_function	protein binding
d	0019013	cellular_component	viral nucleocapsid
d	0019028	cellular_component	viral capsid
d	0019029	cellular_component	helical viral capsid
d	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
d	0030430	cellular_component	host cell cytoplasm
d	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
d	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
d	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
d	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
d	0044423	cellular_component	virion component
d	0052031	biological_process	symbiont-mediated perturbation of host defense response
d	0052170	biological_process	symbiont-mediated suppression of host innate immune response
d	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
d	1990904	cellular_component	ribonucleoprotein complex
g	0003723	molecular_function	RNA binding
g	0005515	molecular_function	protein binding
g	0019013	cellular_component	viral nucleocapsid
g	0019028	cellular_component	viral capsid
g	0019029	cellular_component	helical viral capsid
g	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
g	0030430	cellular_component	host cell cytoplasm
g	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
g	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
g	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
g	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
g	0044423	cellular_component	virion component
g	0052031	biological_process	symbiont-mediated perturbation of host defense response
g	0052170	biological_process	symbiont-mediated suppression of host innate immune response
g	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
g	1990904	cellular_component	ribonucleoprotein complex
h	0003723	molecular_function	RNA binding
h	0005515	molecular_function	protein binding
h	0019013	cellular_component	viral nucleocapsid
h	0019028	cellular_component	viral capsid
h	0019029	cellular_component	helical viral capsid
h	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
h	0030430	cellular_component	host cell cytoplasm
h	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
h	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
h	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
h	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
h	0044423	cellular_component	virion component
h	0052031	biological_process	symbiont-mediated perturbation of host defense response
h	0052170	biological_process	symbiont-mediated suppression of host innate immune response
h	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
h	1990904	cellular_component	ribonucleoprotein complex
k	0003723	molecular_function	RNA binding
k	0005515	molecular_function	protein binding
k	0019013	cellular_component	viral nucleocapsid
k	0019028	cellular_component	viral capsid
k	0019029	cellular_component	helical viral capsid
k	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
k	0030430	cellular_component	host cell cytoplasm
k	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
k	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
k	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
k	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
k	0044423	cellular_component	virion component
k	0052031	biological_process	symbiont-mediated perturbation of host defense response
k	0052170	biological_process	symbiont-mediated suppression of host innate immune response
k	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
k	1990904	cellular_component	ribonucleoprotein complex
l	0003723	molecular_function	RNA binding
l	0005515	molecular_function	protein binding
l	0019013	cellular_component	viral nucleocapsid
l	0019028	cellular_component	viral capsid
l	0019029	cellular_component	helical viral capsid
l	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
l	0030430	cellular_component	host cell cytoplasm
l	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
l	0039545	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
l	0039554	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MDA-5 activity
l	0039580	biological_process	symbiont-mediated suppression of host PKR/eIFalpha signaling
l	0044423	cellular_component	virion component
l	0052031	biological_process	symbiont-mediated perturbation of host defense response
l	0052170	biological_process	symbiont-mediated suppression of host innate immune response
l	0085034	biological_process	symbiont-mediated suppression of host NF-kappaB cascade
l	1990904	cellular_component	ribonucleoprotein complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4420
Details	Region: {"description":"Interaction with the phosphoprotein","evidences":[{"source":"PubMed","id":"22623798","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1440
Details	Region: {"description":"Interaction with the phosphoprotein","evidences":[{"source":"UniProtKB","id":"P22677","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"22019509","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---