8OIQ

39S mammalian mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
Aa	0003747	molecular_function	translation release factor activity
Aa	0005739	cellular_component	mitochondrion
Aa	0005759	cellular_component	mitochondrial matrix
Aa	0006415	biological_process	translational termination
Aa	0016149	molecular_function	translation release factor activity, codon specific
Aa	0070126	biological_process	mitochondrial translational termination
B1	0003735	molecular_function	structural constituent of ribosome
B1	0005739	cellular_component	mitochondrion
B1	0005743	cellular_component	mitochondrial inner membrane
B1	0005759	cellular_component	mitochondrial matrix
B1	0005762	cellular_component	mitochondrial large ribosomal subunit
B1	0005840	cellular_component	ribosome
B1	0006390	biological_process	mitochondrial transcription
B1	0006412	biological_process	translation
B1	0045893	biological_process	positive regulation of DNA-templated transcription
B2	0003735	molecular_function	structural constituent of ribosome
B2	0005739	cellular_component	mitochondrion
B2	0005743	cellular_component	mitochondrial inner membrane
B2	0005759	cellular_component	mitochondrial matrix
B2	0005762	cellular_component	mitochondrial large ribosomal subunit
B2	0005840	cellular_component	ribosome
B2	0006390	biological_process	mitochondrial transcription
B2	0006412	biological_process	translation
B2	0045893	biological_process	positive regulation of DNA-templated transcription
B3	0003735	molecular_function	structural constituent of ribosome
B3	0005739	cellular_component	mitochondrion
B3	0005743	cellular_component	mitochondrial inner membrane
B3	0005759	cellular_component	mitochondrial matrix
B3	0005762	cellular_component	mitochondrial large ribosomal subunit
B3	0005840	cellular_component	ribosome
B3	0006390	biological_process	mitochondrial transcription
B3	0006412	biological_process	translation
B3	0045893	biological_process	positive regulation of DNA-templated transcription
B4	0003735	molecular_function	structural constituent of ribosome
B4	0005739	cellular_component	mitochondrion
B4	0005743	cellular_component	mitochondrial inner membrane
B4	0005759	cellular_component	mitochondrial matrix
B4	0005762	cellular_component	mitochondrial large ribosomal subunit
B4	0005840	cellular_component	ribosome
B4	0006390	biological_process	mitochondrial transcription
B4	0006412	biological_process	translation
B4	0045893	biological_process	positive regulation of DNA-templated transcription
B5	0003735	molecular_function	structural constituent of ribosome
B5	0005739	cellular_component	mitochondrion
B5	0005743	cellular_component	mitochondrial inner membrane
B5	0005759	cellular_component	mitochondrial matrix
B5	0005762	cellular_component	mitochondrial large ribosomal subunit
B5	0005840	cellular_component	ribosome
B5	0006390	biological_process	mitochondrial transcription
B5	0006412	biological_process	translation
B5	0045893	biological_process	positive regulation of DNA-templated transcription
B6	0003735	molecular_function	structural constituent of ribosome
B6	0005739	cellular_component	mitochondrion
B6	0005743	cellular_component	mitochondrial inner membrane
B6	0005759	cellular_component	mitochondrial matrix
B6	0005762	cellular_component	mitochondrial large ribosomal subunit
B6	0005840	cellular_component	ribosome
B6	0006390	biological_process	mitochondrial transcription
B6	0006412	biological_process	translation
B6	0045893	biological_process	positive regulation of DNA-templated transcription
Ba	0003735	molecular_function	structural constituent of ribosome
Ba	0005739	cellular_component	mitochondrion
Ba	0005762	cellular_component	mitochondrial large ribosomal subunit
Ba	0006412	biological_process	translation
Ba	0032543	biological_process	mitochondrial translation
BA	0003735	molecular_function	structural constituent of ribosome
BA	0005739	cellular_component	mitochondrion
BA	0005762	cellular_component	mitochondrial large ribosomal subunit
BA	0005840	cellular_component	ribosome
BA	0006412	biological_process	translation
BA	0015934	cellular_component	large ribosomal subunit
BB	0003735	molecular_function	structural constituent of ribosome
BB	0005739	cellular_component	mitochondrion
BB	0005840	cellular_component	ribosome
BB	0006412	biological_process	translation
BB	0044391	cellular_component	ribosomal subunit
BC	0003723	molecular_function	RNA binding
BC	0003735	molecular_function	structural constituent of ribosome
BC	0005739	cellular_component	mitochondrion
BC	0005762	cellular_component	mitochondrial large ribosomal subunit
BC	0005840	cellular_component	ribosome
BC	0006412	biological_process	translation
Bd	0003735	molecular_function	structural constituent of ribosome
Bd	0005762	cellular_component	mitochondrial large ribosomal subunit
BD	0003735	molecular_function	structural constituent of ribosome
BD	0005840	cellular_component	ribosome
BD	0006412	biological_process	translation
Be	0003735	molecular_function	structural constituent of ribosome
Be	0005739	cellular_component	mitochondrion
Be	0005761	cellular_component	mitochondrial ribosome
Be	0005762	cellular_component	mitochondrial large ribosomal subunit
BE	0003735	molecular_function	structural constituent of ribosome
Bf	0003747	molecular_function	translation release factor activity
Bf	0004045	molecular_function	peptidyl-tRNA hydrolase activity
Bf	0005739	cellular_component	mitochondrion
Bf	0005743	cellular_component	mitochondrial inner membrane
Bf	0005762	cellular_component	mitochondrial large ribosomal subunit
Bf	0006415	biological_process	translational termination
Bf	0016150	molecular_function	translation release factor activity, codon nonspecific
Bf	0070126	biological_process	mitochondrial translational termination
Bf	7770016	biological_process	rescue of stalled mitochondrial ribosome
BF	0003735	molecular_function	structural constituent of ribosome
BF	0005739	cellular_component	mitochondrion
BF	0005761	cellular_component	mitochondrial ribosome
BF	0005762	cellular_component	mitochondrial large ribosomal subunit
BF	0006412	biological_process	translation
BF	0032543	biological_process	mitochondrial translation
Bg	0003735	molecular_function	structural constituent of ribosome
Bg	0005634	cellular_component	nucleus
Bg	0005739	cellular_component	mitochondrion
Bg	0005759	cellular_component	mitochondrial matrix
Bg	0005762	cellular_component	mitochondrial large ribosomal subunit
Bg	0032543	biological_process	mitochondrial translation
BG	0003735	molecular_function	structural constituent of ribosome
BG	0005739	cellular_component	mitochondrion
BG	0005743	cellular_component	mitochondrial inner membrane
BG	0006412	biological_process	translation
BG	0015934	cellular_component	large ribosomal subunit
Bh	0003735	molecular_function	structural constituent of ribosome
Bh	0005840	cellular_component	ribosome
Bh	0006412	biological_process	translation
BH	0003735	molecular_function	structural constituent of ribosome
BH	0005739	cellular_component	mitochondrion
BH	0005762	cellular_component	mitochondrial large ribosomal subunit
BH	0006412	biological_process	translation
BH	0015934	cellular_component	large ribosomal subunit
Bi	0003735	molecular_function	structural constituent of ribosome
Bi	0005739	cellular_component	mitochondrion
Bi	0005762	cellular_component	mitochondrial large ribosomal subunit
Bi	0005840	cellular_component	ribosome
Bi	0006412	biological_process	translation
BI	0003735	molecular_function	structural constituent of ribosome
BI	0005737	cellular_component	cytoplasm
BI	0005739	cellular_component	mitochondrion
BI	0005762	cellular_component	mitochondrial large ribosomal subunit
BI	0005840	cellular_component	ribosome
BI	0006412	biological_process	translation
Bj	0003723	molecular_function	RNA binding
Bj	0003735	molecular_function	structural constituent of ribosome
Bj	0005739	cellular_component	mitochondrion
Bj	0005743	cellular_component	mitochondrial inner membrane
Bj	0006412	biological_process	translation
Bj	0015934	cellular_component	large ribosomal subunit
BJ	0003735	molecular_function	structural constituent of ribosome
BJ	0005739	cellular_component	mitochondrion
BJ	0005762	cellular_component	mitochondrial large ribosomal subunit
BJ	0005840	cellular_component	ribosome
BJ	0006412	biological_process	translation
BK	0003735	molecular_function	structural constituent of ribosome
BK	0005739	cellular_component	mitochondrion
BK	0005840	cellular_component	ribosome
BK	0006412	biological_process	translation
Bl	0003735	molecular_function	structural constituent of ribosome
Bl	0005739	cellular_component	mitochondrion
Bl	0005762	cellular_component	mitochondrial large ribosomal subunit
Bl	0005840	cellular_component	ribosome
Bl	0006412	biological_process	translation
BL	0003735	molecular_function	structural constituent of ribosome
BL	0005739	cellular_component	mitochondrion
BL	0005743	cellular_component	mitochondrial inner membrane
BL	0005762	cellular_component	mitochondrial large ribosomal subunit
BL	0005840	cellular_component	ribosome
BL	0006412	biological_process	translation
BL	0032543	biological_process	mitochondrial translation
Bm	0003735	molecular_function	structural constituent of ribosome
Bm	0005739	cellular_component	mitochondrion
Bm	0005762	cellular_component	mitochondrial large ribosomal subunit
Bm	0005840	cellular_component	ribosome
Bm	0006412	biological_process	translation
BM	0003735	molecular_function	structural constituent of ribosome
BM	0005739	cellular_component	mitochondrion
BM	0005743	cellular_component	mitochondrial inner membrane
BM	0005762	cellular_component	mitochondrial large ribosomal subunit
BM	0005840	cellular_component	ribosome
BM	0006412	biological_process	translation
Bn	0005739	cellular_component	mitochondrion
Bn	0005743	cellular_component	mitochondrial inner membrane
Bn	0005762	cellular_component	mitochondrial large ribosomal subunit
BN	0003735	molecular_function	structural constituent of ribosome
BN	0005739	cellular_component	mitochondrion
BN	0005743	cellular_component	mitochondrial inner membrane
BN	0005840	cellular_component	ribosome
BN	0006412	biological_process	translation
Bo	0000166	molecular_function	nucleotide binding
Bo	0005739	cellular_component	mitochondrion
BO	0003735	molecular_function	structural constituent of ribosome
BO	0005739	cellular_component	mitochondrion
BO	0005762	cellular_component	mitochondrial large ribosomal subunit
BO	0005840	cellular_component	ribosome
BO	0006412	biological_process	translation
Bp	0005739	cellular_component	mitochondrion
Bp	0005762	cellular_component	mitochondrial large ribosomal subunit
BP	0005739	cellular_component	mitochondrion
BP	0005743	cellular_component	mitochondrial inner membrane
BP	0005762	cellular_component	mitochondrial large ribosomal subunit
Bq	0003735	molecular_function	structural constituent of ribosome
Bq	0005739	cellular_component	mitochondrion
Bq	0005762	cellular_component	mitochondrial large ribosomal subunit
Bq	0006412	biological_process	translation
Bq	1990904	cellular_component	ribonucleoprotein complex
BQ	0003735	molecular_function	structural constituent of ribosome
BQ	0005840	cellular_component	ribosome
BQ	0006412	biological_process	translation
Br	0005739	cellular_component	mitochondrion
Br	0005762	cellular_component	mitochondrial large ribosomal subunit
BR	0003735	molecular_function	structural constituent of ribosome
BR	0005739	cellular_component	mitochondrion
BR	0005761	cellular_component	mitochondrial ribosome
BR	0005762	cellular_component	mitochondrial large ribosomal subunit
BR	0005840	cellular_component	ribosome
BR	0006412	biological_process	translation
BR	0017148	biological_process	negative regulation of translation
Bs	0003735	molecular_function	structural constituent of ribosome
Bs	0005739	cellular_component	mitochondrion
Bs	0005743	cellular_component	mitochondrial inner membrane
Bs	0032543	biological_process	mitochondrial translation
BS	0003735	molecular_function	structural constituent of ribosome
BS	0005739	cellular_component	mitochondrion
BS	0005743	cellular_component	mitochondrial inner membrane
BS	0005840	cellular_component	ribosome
BS	0006412	biological_process	translation
Bt	0003723	molecular_function	RNA binding
Bt	0003725	molecular_function	double-stranded RNA binding
Bt	0004525	molecular_function	ribonuclease III activity
Bt	0005739	cellular_component	mitochondrion
Bt	0005759	cellular_component	mitochondrial matrix
Bt	0005762	cellular_component	mitochondrial large ribosomal subunit
Bt	0006396	biological_process	RNA processing
Bt	0070125	biological_process	mitochondrial translational elongation
BT	0003735	molecular_function	structural constituent of ribosome
BT	0005739	cellular_component	mitochondrion
BT	0005762	cellular_component	mitochondrial large ribosomal subunit
BT	0006412	biological_process	translation
BT	0015934	cellular_component	large ribosomal subunit
Bu	0005739	cellular_component	mitochondrion
BU	0003735	molecular_function	structural constituent of ribosome
BU	0005739	cellular_component	mitochondrion
BU	0005743	cellular_component	mitochondrial inner membrane
BU	0005762	cellular_component	mitochondrial large ribosomal subunit
BU	0005840	cellular_component	ribosome
BU	0006412	biological_process	translation
BU	0019843	molecular_function	rRNA binding
BU	0032543	biological_process	mitochondrial translation
Bv	0003735	molecular_function	structural constituent of ribosome
Bv	0005739	cellular_component	mitochondrion
Bv	0005743	cellular_component	mitochondrial inner membrane
Bv	0005762	cellular_component	mitochondrial large ribosomal subunit
BV	0003735	molecular_function	structural constituent of ribosome
BV	0005739	cellular_component	mitochondrion
BV	0005762	cellular_component	mitochondrial large ribosomal subunit
BV	0005840	cellular_component	ribosome
BV	0006412	biological_process	translation
BV	0019904	molecular_function	protein domain specific binding
Bw	0005739	cellular_component	mitochondrion
Bw	0005743	cellular_component	mitochondrial inner membrane
Bw	0005761	cellular_component	mitochondrial ribosome
Bw	0005762	cellular_component	mitochondrial large ribosomal subunit
BW	0003735	molecular_function	structural constituent of ribosome
BW	0005739	cellular_component	mitochondrion
BW	0005743	cellular_component	mitochondrial inner membrane
BW	0005840	cellular_component	ribosome
BW	0006412	biological_process	translation
Bx	0003735	molecular_function	structural constituent of ribosome
Bx	0005739	cellular_component	mitochondrion
Bx	0005761	cellular_component	mitochondrial ribosome
Bx	0005762	cellular_component	mitochondrial large ribosomal subunit
Bx	0005840	cellular_component	ribosome
Bx	0006412	biological_process	translation
BX	0003735	molecular_function	structural constituent of ribosome
BX	0005739	cellular_component	mitochondrion
BX	0005840	cellular_component	ribosome
BX	0006412	biological_process	translation
By	0005739	cellular_component	mitochondrion
By	0005762	cellular_component	mitochondrial large ribosomal subunit
BY	0003735	molecular_function	structural constituent of ribosome
BY	0005739	cellular_component	mitochondrion
BY	0005761	cellular_component	mitochondrial ribosome
BY	0005762	cellular_component	mitochondrial large ribosomal subunit
BY	0005840	cellular_component	ribosome
BY	0006412	biological_process	translation
BY	0015934	cellular_component	large ribosomal subunit
BY	0019843	molecular_function	rRNA binding
Bz	0003735	molecular_function	structural constituent of ribosome
Bz	0005739	cellular_component	mitochondrion
Bz	0005761	cellular_component	mitochondrial ribosome
Bz	0005762	cellular_component	mitochondrial large ribosomal subunit
BZ	0003723	molecular_function	RNA binding
BZ	0003735	molecular_function	structural constituent of ribosome
BZ	0005737	cellular_component	cytoplasm
BZ	0005840	cellular_component	ribosome
BZ	0006412	biological_process	translation

Functional Information from PROSITE/UniProt

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FrpgqyvDvtAkTiGKGfqGvmrR

Chain	Residue	Details
BM	PHE198-ARG221

---

site_id	PS00745
Number of Residues	17
Details	RF_PROK_I Prokaryotic-type class I peptide chain release factors signature. RAkGaGGQHVNktdSAV

Chain	Residue	Details
Aa	ARG306-VAL322

---

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. IYGMLPknlh.RRtmmqrLhLFpD

Chain	Residue	Details
BR	ILE108-ASP130

---

site_id	PS01108
Number of Residues	18
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. GDkVeILeGkdAGkq.GkV

Chain	Residue	Details
BC	GLY59-VAL76

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI32
Number of Residues	64
Details	Region: {"description":"GGQ domain","evidences":[{"source":"UniProtKB","id":"Q80VP5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	2
Details	Motif: {"description":"GGQ","evidences":[{"source":"PubMed","id":"37141370","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	1
Details	Modified residue: {"description":"N5-methylglutamine","evidences":[{"source":"PubMed","id":"35260756","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---