8KGV
Molecular mechanism of prostaglandin transporter SLCO2A1
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 106 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-LYS32 | |
| A | SER93-PRO98 | |
| A | ASP197-SER215 | |
| A | ARG280-ARG321 | |
| A | LYS388-VAL391 | |
| A | ARG542-SER550 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 19 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL33-PHE52 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 232 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS53-GLY71 | |
| A | PRO124-SER167 | |
| A | GLY237-ILE254 | |
| A | GLY344-TYR363 | |
| A | PHE416-ALA518 | |
| A | ASP577-GLN610 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU72-GLY92 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | ARG99-GLU123 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 28 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | SER168-ASP196 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL216-TYR236 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY255-PRO279 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU322-ALA343 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA364-MET387 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 23 |
| Details | TRANSMEM: Helical; Name=9 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE392-LEU415 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 22 |
| Details | TRANSMEM: Helical; Name=10 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE519-LEU541 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=11 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE551-ILE576 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 18 |
| Details | TRANSMEM: Helical; Name=12 => ECO:0000255 |
| Chain | Residue | Details |
| A | MET611-LYS629 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN134 | |
| A | ASN478 | |
| A | ASN491 |
