8KGI
Molecular mechanism of prostaglandin transporter SLCO2A1
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 238 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | MET1-LYS32 | |
| B | ASP197-SER215 | |
| B | ARG280-ARG321 | |
| B | LYS388-VAL391 | |
| B | ARG542-SER550 | |
| B | LYS630-ILE643 | |
| A | SER93-PRO98 | |
| A | ASP197-SER215 | |
| A | ARG280-ARG321 | |
| A | LYS388-VAL391 | |
| A | ARG542-SER550 | |
| A | LYS630-ILE643 | |
| B | MET1-LYS32 | |
| B | SER93-PRO98 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL33-PHE52 | |
| B | VAL33-PHE52 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 464 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS53-GLY71 | |
| B | GLY344-TYR363 | |
| B | PHE416-ALA518 | |
| B | ASP577-GLN610 | |
| A | PRO124-SER167 | |
| A | GLY237-ILE254 | |
| A | GLY344-TYR363 | |
| A | PHE416-ALA518 | |
| A | ASP577-GLN610 | |
| B | LYS53-GLY71 | |
| B | PRO124-SER167 | |
| B | GLY237-ILE254 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU72-GLY92 | |
| B | LEU72-GLY92 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 48 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | ARG99-GLU123 | |
| B | ARG99-GLU123 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 56 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | SER168-ASP196 | |
| B | SER168-ASP196 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL216-TYR236 | |
| B | VAL216-TYR236 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 48 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY255-PRO279 | |
| B | GLY255-PRO279 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU322-ALA343 | |
| B | LEU322-ALA343 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 46 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA364-MET387 | |
| B | ALA364-MET387 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 46 |
| Details | TRANSMEM: Helical; Name=9 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE392-LEU415 | |
| B | PHE392-LEU415 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 44 |
| Details | TRANSMEM: Helical; Name=10 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE519-LEU541 | |
| B | ILE519-LEU541 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 50 |
| Details | TRANSMEM: Helical; Name=11 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE551-ILE576 | |
| B | PHE551-ILE576 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 36 |
| Details | TRANSMEM: Helical; Name=12 => ECO:0000255 |
| Chain | Residue | Details |
| A | MET611-LYS629 | |
| B | MET611-LYS629 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN134 | |
| A | ASN478 | |
| A | ASN491 | |
| B | ASN134 | |
| B | ASN478 | |
| B | ASN491 |
