8KE6

PylRS C-terminus domain mutant bound with L-3-chlorophenylalanine and AMPNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0043039	biological_process	tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	27
Details	binding site for residue ANP A 501

Chain	Residue
A	ARG330
A	SER399
A	GLY423
A	ARG426
A	MG502
A	MG503
A	HOH607
A	HOH616
A	HOH619
A	HOH632
A	HOH638
A	GLU332
A	HOH646
A	HOH651
A	HOH666
A	HOH689
A	HOH696
A	HOH722
A	HOH727
A	HOH744
A	HIS338
A	LEU339
A	PHE342
A	MET344
A	GLU396
A	LEU397
A	SER398

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site_id	AC2
Number of Residues	5
Details	binding site for residue MG A 502

Chain	Residue
A	GLU396
A	SER399
A	ANP501
A	HOH619
A	HOH744

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site_id	AC3
Number of Residues	5
Details	binding site for residue MG A 503

Chain	Residue
A	ANP501
A	HOH616
A	HOH666
A	HOH689
A	HOH696

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site_id	AC4
Number of Residues	10
Details	binding site for residue FCL A 504

Chain	Residue
A	MET300
A	LEU301
A	ALA302
A	MET344
A	GLY401
A	GLY419
A	ALA420
A	GLY421
A	HOH646
A	HOH730

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