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8KC7

Rpd3S histone deacetylase complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000082biological_processG1/S transition of mitotic cell cycle
A0000086biological_processG2/M transition of mitotic cell cycle
A0000118cellular_componenthistone deacetylase complex
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0003713molecular_functiontranscription coactivator activity
A0003714molecular_functiontranscription corepressor activity
A0004407molecular_functionhistone deacetylase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0006325biological_processchromatin organization
A0006334biological_processnucleosome assembly
A0006355biological_processregulation of DNA-templated transcription
A0006357biological_processregulation of transcription by RNA polymerase II
A0006368biological_processtranscription elongation by RNA polymerase II
A0006979biological_processresponse to oxidative stress
A0006995biological_processcellular response to nitrogen starvation
A0008270molecular_functionzinc ion binding
A0016239biological_processpositive regulation of macroautophagy
A0016479biological_processnegative regulation of transcription by RNA polymerase I
A0016787molecular_functionhydrolase activity
A0030174biological_processregulation of DNA-templated DNA replication initiation
A0031507biological_processheterochromatin formation
A0032221cellular_componentRpd3S complex
A0033698cellular_componentRpd3L complex
A0034399cellular_componentnuclear periphery
A0034503biological_processprotein localization to nucleolar rDNA repeats
A0034605biological_processcellular response to heat
A0044804biological_processnucleophagy
A0045128biological_processnegative regulation of reciprocal meiotic recombination
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0051321biological_processmeiotic cell cycle
A0061186biological_processnegative regulation of silent mating-type cassette heterochromatin formation
A0061188biological_processnegative regulation of rDNA heterochromatin formation
A0070210cellular_componentRpd3L-Expanded complex
A0070211cellular_componentSnt2C complex
A0070550biological_processrDNA chromatin condensation
A0070822cellular_componentSin3-type complex
B0003714molecular_functiontranscription corepressor activity
B0006355biological_processregulation of DNA-templated transcription
D0000122biological_processnegative regulation of transcription by RNA polymerase II
D0000123cellular_componenthistone acetyltransferase complex
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0006281biological_processDNA repair
D0006325biological_processchromatin organization
D0006334biological_processnucleosome assembly
D0006335biological_processDNA replication-dependent chromatin assembly
D0006337biological_processnucleosome disassembly
D0006338biological_processchromatin remodeling
D0006351biological_processDNA-templated transcription
D0006355biological_processregulation of DNA-templated transcription
D0006357biological_processregulation of transcription by RNA polymerase II
D0006368biological_processtranscription elongation by RNA polymerase II
D0009889biological_processregulation of biosynthetic process
D0030174biological_processregulation of DNA-templated DNA replication initiation
D0032221cellular_componentRpd3S complex
D0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
D0035064molecular_functionmethylated histone binding
D0035267cellular_componentNuA4 histone acetyltransferase complex
D0043487biological_processregulation of RNA stability
D0045892biological_processnegative regulation of DNA-templated transcription
D0060195biological_processnegative regulation of antisense RNA transcription
D1990453cellular_componentnucleosome disassembly/reassembly complex
E0000118cellular_componenthistone deacetylase complex
E0000122biological_processnegative regulation of transcription by RNA polymerase II
E0005634cellular_componentnucleus
E0006325biological_processchromatin organization
E0006334biological_processnucleosome assembly
E0006357biological_processregulation of transcription by RNA polymerase II
E0006368biological_processtranscription elongation by RNA polymerase II
E0008270molecular_functionzinc ion binding
E0030174biological_processregulation of DNA-templated DNA replication initiation
E0032221cellular_componentRpd3S complex
E0045944biological_processpositive regulation of transcription by RNA polymerase II
E0046872molecular_functionmetal ion binding
E0060195biological_processnegative regulation of antisense RNA transcription
F0000122biological_processnegative regulation of transcription by RNA polymerase II
F0000123cellular_componenthistone acetyltransferase complex
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0006281biological_processDNA repair
F0006325biological_processchromatin organization
F0006334biological_processnucleosome assembly
F0006335biological_processDNA replication-dependent chromatin assembly
F0006337biological_processnucleosome disassembly
F0006338biological_processchromatin remodeling
F0006351biological_processDNA-templated transcription
F0006355biological_processregulation of DNA-templated transcription
F0006357biological_processregulation of transcription by RNA polymerase II
F0006368biological_processtranscription elongation by RNA polymerase II
F0009889biological_processregulation of biosynthetic process
F0030174biological_processregulation of DNA-templated DNA replication initiation
F0032221cellular_componentRpd3S complex
F0032968biological_processpositive regulation of transcription elongation by RNA polymerase II
F0035064molecular_functionmethylated histone binding
F0035267cellular_componentNuA4 histone acetyltransferase complex
F0043487biological_processregulation of RNA stability
F0045892biological_processnegative regulation of DNA-templated transcription
F0060195biological_processnegative regulation of antisense RNA transcription
F1990453cellular_componentnucleosome disassembly/reassembly complex
G0000118cellular_componenthistone deacetylase complex
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0005634cellular_componentnucleus
G0006325biological_processchromatin organization
G0006334biological_processnucleosome assembly
G0006357biological_processregulation of transcription by RNA polymerase II
G0006368biological_processtranscription elongation by RNA polymerase II
G0008270molecular_functionzinc ion binding
G0030174biological_processregulation of DNA-templated DNA replication initiation
G0032221cellular_componentRpd3S complex
G0045944biological_processpositive regulation of transcription by RNA polymerase II
G0046872molecular_functionmetal ion binding
G0060195biological_processnegative regulation of antisense RNA transcription
Functional Information from PROSITE/UniProt
site_idPS01359
Number of Residues44
DetailsZF_PHD_1 Zinc finger PHD-type signature. CsaCnqsgsf.......................................LcCdt..Cpks.FHflCldppidpnnlpkgd...............................WhCneC
ChainResidueDetails
ECYS263-CYS306

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues98
DetailsZN_FING: PHD-type 1 => ECO:0000255|PROSITE-ProRule:PRU00146
ChainResidueDetails
EGLU260-LYS309
GGLU260-LYS309

site_idSWS_FT_FI2
Number of Residues116
DetailsZN_FING: PHD-type 2; atypical => ECO:0000255|PROSITE-ProRule:PRU00146
ChainResidueDetails
EPHE414-THR472
GPHE414-THR472

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22814378
ChainResidueDetails
EMET1
GMET1

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956
ChainResidueDetails
ESER68
GSER68

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
ESER683
GSER683

224004

PDB entries from 2024-08-21

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