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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8KBZ

Cryo-EM structure of human ATG9A in LMNG micelles

Functional Information from GO Data
ChainGOidnamespacecontents
A0000045biological_processautophagosome assembly
A0000139cellular_componentGolgi membrane
A0000407cellular_componentphagophore assembly site
A0000421cellular_componentautophagosome membrane
A0000423biological_processmitophagy
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005768cellular_componentendosome
A0005770cellular_componentlate endosome
A0005776cellular_componentautophagosome
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005794cellular_componentGolgi apparatus
A0005802cellular_componenttrans-Golgi network
A0006869biological_processlipid transport
A0006914biological_processautophagy
A0010936biological_processnegative regulation of macrophage cytokine production
A0016020cellular_componentmembrane
A0017121biological_processplasma membrane phospholipid scrambling
A0017128molecular_functionphospholipid scramblase activity
A0031410cellular_componentcytoplasmic vesicle
A0031902cellular_componentlate endosome membrane
A0031966cellular_componentmitochondrial membrane
A0032688biological_processnegative regulation of interferon-beta production
A0034045cellular_componentphagophore assembly site membrane
A0034067biological_processprotein localization to Golgi apparatus
A0034497biological_processprotein localization to phagophore assembly site
A0034727biological_processpiecemeal microautophagy of the nucleus
A0045087biological_processinnate immune response
A0055037cellular_componentrecycling endosome
A0055038cellular_componentrecycling endosome membrane
A0060349biological_processbone morphogenesis
A0061709biological_processreticulophagy
A0097060cellular_componentsynaptic membrane
A0097300biological_processprogrammed necrotic cell death
B0000045biological_processautophagosome assembly
B0000139cellular_componentGolgi membrane
B0000407cellular_componentphagophore assembly site
B0000421cellular_componentautophagosome membrane
B0000423biological_processmitophagy
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005768cellular_componentendosome
B0005770cellular_componentlate endosome
B0005776cellular_componentautophagosome
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0005794cellular_componentGolgi apparatus
B0005802cellular_componenttrans-Golgi network
B0006869biological_processlipid transport
B0006914biological_processautophagy
B0010936biological_processnegative regulation of macrophage cytokine production
B0016020cellular_componentmembrane
B0017121biological_processplasma membrane phospholipid scrambling
B0017128molecular_functionphospholipid scramblase activity
B0031410cellular_componentcytoplasmic vesicle
B0031902cellular_componentlate endosome membrane
B0031966cellular_componentmitochondrial membrane
B0032688biological_processnegative regulation of interferon-beta production
B0034045cellular_componentphagophore assembly site membrane
B0034067biological_processprotein localization to Golgi apparatus
B0034497biological_processprotein localization to phagophore assembly site
B0034727biological_processpiecemeal microautophagy of the nucleus
B0045087biological_processinnate immune response
B0055037cellular_componentrecycling endosome
B0055038cellular_componentrecycling endosome membrane
B0060349biological_processbone morphogenesis
B0061709biological_processreticulophagy
B0097060cellular_componentsynaptic membrane
B0097300biological_processprogrammed necrotic cell death
C0000045biological_processautophagosome assembly
C0000139cellular_componentGolgi membrane
C0000407cellular_componentphagophore assembly site
C0000421cellular_componentautophagosome membrane
C0000423biological_processmitophagy
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005768cellular_componentendosome
C0005770cellular_componentlate endosome
C0005776cellular_componentautophagosome
C0005783cellular_componentendoplasmic reticulum
C0005789cellular_componentendoplasmic reticulum membrane
C0005794cellular_componentGolgi apparatus
C0005802cellular_componenttrans-Golgi network
C0006869biological_processlipid transport
C0006914biological_processautophagy
C0010936biological_processnegative regulation of macrophage cytokine production
C0016020cellular_componentmembrane
C0017121biological_processplasma membrane phospholipid scrambling
C0017128molecular_functionphospholipid scramblase activity
C0031410cellular_componentcytoplasmic vesicle
C0031902cellular_componentlate endosome membrane
C0031966cellular_componentmitochondrial membrane
C0032688biological_processnegative regulation of interferon-beta production
C0034045cellular_componentphagophore assembly site membrane
C0034067biological_processprotein localization to Golgi apparatus
C0034497biological_processprotein localization to phagophore assembly site
C0034727biological_processpiecemeal microautophagy of the nucleus
C0045087biological_processinnate immune response
C0055037cellular_componentrecycling endosome
C0055038cellular_componentrecycling endosome membrane
C0060349biological_processbone morphogenesis
C0061709biological_processreticulophagy
C0097060cellular_componentsynaptic membrane
C0097300biological_processprogrammed necrotic cell death
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues267
DetailsTransmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"32610138","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33106659","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WQZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLQ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues723
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues30
DetailsIntramembrane: {"evidences":[{"source":"PubMed","id":"32610138","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33106659","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WQZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLQ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues24
DetailsIntramembrane: {"evidences":[{"source":"PubMed","id":"32610138","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33106659","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WQZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WR4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLQ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues24
DetailsTopological domain: {"description":"Lumenal","evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues27
DetailsIntramembrane: {"evidences":[{"source":"PubMed","id":"32610138","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WQZ","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues24
DetailsIntramembrane: {"evidences":[{"source":"PubMed","id":"32610138","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33106659","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WQZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7JLP","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

238895

PDB entries from 2025-07-16

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