8KA1
Crystal structure of Vibrio vulnificus RID-dependent transforming NADase domain (RDTND)/calmodulin-binding domain of Rho inactivation domain (RID-CBD) complexed with Ca2+-free calmodulin
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL |
| Chain | Residue | Details |
| B | ASP21-LEU33 | |
| B | ASP57-PHE69 | |
| B | ASP94-LEU106 | |
| B | ASP130-PHE142 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 80 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:1474585 |
| Chain | Residue | Details |
| B | ASP21 | |
| B | GLU68 | |
| B | ASP94 | |
| B | ASP96 | |
| B | ASN98 | |
| B | TYR100 | |
| B | GLU105 | |
| B | ASP130 | |
| B | ASP132 | |
| B | ASP134 | |
| B | GLN136 | |
| B | ASP23 | |
| B | GLU141 | |
| D | ASP21 | |
| D | ASP23 | |
| D | ASP25 | |
| D | THR27 | |
| D | GLU32 | |
| D | ASP57 | |
| D | ASP59 | |
| D | ASN61 | |
| D | THR63 | |
| B | ASP25 | |
| D | GLU68 | |
| D | ASP94 | |
| D | ASP96 | |
| D | ASN98 | |
| D | TYR100 | |
| D | GLU105 | |
| D | ASP130 | |
| D | ASP132 | |
| D | ASP134 | |
| D | GLN136 | |
| B | THR27 | |
| D | GLU141 | |
| F | ASP21 | |
| F | ASP23 | |
| F | ASP25 | |
| F | THR27 | |
| F | GLU32 | |
| F | ASP57 | |
| F | ASP59 | |
| F | ASN61 | |
| F | THR63 | |
| B | GLU32 | |
| F | GLU68 | |
| F | ASP94 | |
| F | ASP96 | |
| F | ASN98 | |
| F | TYR100 | |
| F | GLU105 | |
| F | ASP130 | |
| F | ASP132 | |
| F | ASP134 | |
| F | GLN136 | |
| B | ASP57 | |
| F | GLU141 | |
| H | ASP21 | |
| H | ASP23 | |
| H | ASP25 | |
| H | THR27 | |
| H | GLU32 | |
| H | ASP57 | |
| H | ASP59 | |
| H | ASN61 | |
| H | THR63 | |
| B | ASP59 | |
| H | GLU68 | |
| H | ASP94 | |
| H | ASP96 | |
| H | ASN98 | |
| H | TYR100 | |
| H | GLU105 | |
| H | ASP130 | |
| H | ASP132 | |
| H | ASP134 | |
| H | GLN136 | |
| B | ASN61 | |
| H | GLU141 | |
| B | THR63 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: N-acetylalanine => ECO:0000269|PubMed:7093203, ECO:0000269|Ref.9, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712 |
| Chain | Residue | Details |
| B | ALA2 | |
| D | ALA2 | |
| F | ALA2 | |
| H | ALA2 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| B | LYS22 | |
| D | LYS22 | |
| F | LYS22 | |
| H | LYS22 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by CaMK4 => ECO:0000250|UniProtKB:P0DP30 |
| Chain | Residue | Details |
| B | THR45 | |
| D | THR45 | |
| F | THR45 | |
| H | THR45 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| B | SER82 | |
| D | SER82 | |
| F | SER82 | |
| H | SER82 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| B | LYS95 | |
| D | LYS95 | |
| F | LYS95 | |
| H | LYS95 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332 |
| Chain | Residue | Details |
| B | TYR100 | |
| D | TYR100 | |
| F | TYR100 | |
| H | TYR100 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| B | SER102 | |
| D | SER102 | |
| F | SER102 | |
| H | SER102 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| B | THR111 | |
| D | THR111 | |
| F | THR111 | |
| H | THR111 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0007744|PubMed:24129315 |
| Chain | Residue | Details |
| B | LYS116 | |
| D | LYS116 | |
| F | LYS116 | |
| H | LYS116 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:19690332 |
| Chain | Residue | Details |
| B | TYR139 | |
| D | TYR139 | |
| F | TYR139 | |
| H | TYR139 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250|UniProtKB:P62157 |
| Chain | Residue | Details |
| B | LYS22 | |
| D | LYS22 | |
| F | LYS22 | |
| H | LYS22 |
