8K1L

Cryo-EM structure of Na+,K+-ATPase alpha2 from Artemia salina in cation-free E2P form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005215	molecular_function	transporter activity
A	0005391	molecular_function	P-type sodium:potassium-exchanging transporter activity
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006813	biological_process	potassium ion transport
A	0006814	biological_process	sodium ion transport
A	0006883	biological_process	intracellular sodium ion homeostasis
A	0008556	molecular_function	P-type potassium transmembrane transporter activity
A	0010248	biological_process	establishment or maintenance of transmembrane electrochemical gradient
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0030007	biological_process	intracellular potassium ion homeostasis
A	0036376	biological_process	sodium ion export across plasma membrane
A	0046872	molecular_function	metal ion binding
A	1902600	biological_process	proton transmembrane transport
A	1990573	biological_process	potassium ion import across plasma membrane
B	0005890	cellular_component	sodium:potassium-exchanging ATPase complex
B	0006813	biological_process	potassium ion transport
B	0006814	biological_process	sodium ion transport

Functional Information from PROSITE/UniProt

site_id	PS00154
Number of Residues	7
Details	ATPASE_E1_E2 E1-E2 ATPases phosphorylation site. DKTGTLT

Chain	Residue	Details
A	ASP353-THR359

site_id	PS00390
Number of Residues	21
Details	ATPASE_NA_K_BETA_1 Sodium and potassium ATPases beta subunits signature 1. VktFiWNsetsefMGRTgvnW

Chain	Residue	Details
B	VAL43-TRP63

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: 4-aspartylphosphate intermediate => ECO:0000305

Chain	Residue	Details
A	ASP353