8K0E

Human collagen prolyl processing enzyme complex, P3H1/CRTAP heterodimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0031418	molecular_function	L-ascorbic acid binding
A	0032963	biological_process	collagen metabolic process

Functional Information from PROSITE/UniProt

site_id	PS00014
Number of Residues	4
Details	ER_TARGET Endoplasmic reticulum targeting sequence. KDEL

Chain	Residue	Details
A	LYS733-LEU736

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	33
Details	Repeat: {"description":"TPR 1"}

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site_id	SWS_FT_FI2
Number of Residues	33
Details	Repeat: {"description":"TPR 2"}

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site_id	SWS_FT_FI3
Number of Residues	33
Details	Repeat: {"description":"TPR 3"}

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site_id	SWS_FT_FI4
Number of Residues	33
Details	Repeat: {"description":"TPR 4"}

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site_id	SWS_FT_FI5
Number of Residues	114
Details	Domain: {"description":"Fe2OG dioxygenase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"}]}

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"39245686","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8K0M","evidenceCode":"ECO:0007744"}]}

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site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"39245686","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8K0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K17","evidenceCode":"ECO:0007744"}]}

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site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"39245686","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8K0E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K0F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K17","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8KC9","evidenceCode":"ECO:0007744"}]}

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site_id	SWS_FT_FI9
Number of Residues	3
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"39245686","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8K0F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K0I","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K17","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8KC9","evidenceCode":"ECO:0007744"}]}

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site_id	SWS_FT_FI10
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

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site_id	SWS_FT_FI11
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39245686","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8K0F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K0M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8K17","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8KC9","evidenceCode":"ECO:0007744"}]}

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