8K0B
Cryo-EM structure of TMEM63C
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003094 | biological_process | glomerular filtration |
| A | 0005227 | molecular_function | calcium-activated cation channel activity |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006812 | biological_process | monoatomic cation transport |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0098655 | biological_process | monoatomic cation transmembrane transport |
| A | 1990760 | molecular_function | osmolarity-sensing monoatomic cation channel activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 200 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE33-LEU53 | |
| A | LEU685-GLY705 | |
| A | TYR135-VAL155 | |
| A | PHE182-GLY202 | |
| A | ILE409-ILE429 | |
| A | SER455-LEU475 | |
| A | ILE494-PHE514 | |
| A | GLY540-MET560 | |
| A | VAL604-LEU624 | |
| A | VAL655-LEU675 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079 |
| Chain | Residue | Details |
| A | SER75 | |
| A | SER78 |
