8JXM

Human 3-methylcrotonyl-CoA carboxylase in BCCP-H2 state with MCoA

Functional Information from PROSITE/UniProt

site_id	PS00188
Number of Residues	18
Details	BIOTIN Biotin-requiring enzymes attachment site. GDsLmvMiAMKMehtIkS

Chain	Residue	Details
L	GLY671-SER688

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site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. FMEMNTRL

Chain	Residue	Details
L	PHE333-LEU340

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P24182

Chain	Residue	Details
L	ARG339
E	LYS495
J	LYS70
J	LYS495
B	ARG339
F	ARG339
G	ARG339
I	ARG339
M	ARG339
H	LYS70
H	LYS495
E	LYS70

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site_id	SWS_FT_FI2
Number of Residues	36
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P24182

Chain	Residue	Details
L	LYS163
B	HIS255
B	HIS282
B	GLU322
F	LYS163
F	LYS205
F	GLY211
F	HIS255
F	HIS282
F	GLU322
G	LYS163
L	LYS205
G	LYS205
G	GLY211
G	HIS255
G	HIS282
G	GLU322
I	LYS163
I	LYS205
I	GLY211
I	HIS255
I	HIS282
L	GLY211
I	GLU322
M	LYS163
M	LYS205
M	GLY211
M	HIS255
M	HIS282
M	GLU322
L	HIS255
L	HIS282
L	GLU322
B	LYS163
B	LYS205
B	GLY211

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site_id	SWS_FT_FI3
Number of Residues	12
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q99MR8

Chain	Residue	Details
L	LYS237
I	LYS494
M	LYS237
M	LYS494
L	LYS494
B	LYS237
B	LYS494
F	LYS237
F	LYS494
G	LYS237
G	LYS494
I	LYS237

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site_id	SWS_FT_FI4
Number of Residues	6
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q99MR8

Chain	Residue	Details
L	LYS581
B	LYS581
F	LYS581
G	LYS581
I	LYS581
M	LYS581

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site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: N6-biotinyllysine => ECO:0000255|PROSITE-ProRule:PRU01066

Chain	Residue	Details
L	LYS681
B	LYS681
F	LYS681
G	LYS681
I	LYS681
M	LYS681

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