Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8JSG

Structure of the 30S-IF3 complex from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0002181	biological_process	cytoplasmic translation
1	0003735	molecular_function	structural constituent of ribosome
1	0005515	molecular_function	protein binding
1	0005737	cellular_component	cytoplasm
1	0005829	cellular_component	cytosol
1	0005840	cellular_component	ribosome
1	0006412	biological_process	translation
1	0019843	molecular_function	rRNA binding
1	0022627	cellular_component	cytosolic small ribosomal subunit
1	0048027	molecular_function	mRNA 5'-UTR binding
1	0070181	molecular_function	small ribosomal subunit rRNA binding
1	1990904	cellular_component	ribonucleoprotein complex
2	0003735	molecular_function	structural constituent of ribosome
2	0005840	cellular_component	ribosome
2	0006412	biological_process	translation
3	0000028	biological_process	ribosomal small subunit assembly
3	0002181	biological_process	cytoplasmic translation
3	0003723	molecular_function	RNA binding
3	0003735	molecular_function	structural constituent of ribosome
3	0005737	cellular_component	cytoplasm
3	0005829	cellular_component	cytosol
3	0005840	cellular_component	ribosome
3	0006412	biological_process	translation
3	0008073	molecular_function	ornithine decarboxylase inhibitor activity
3	0015935	cellular_component	small ribosomal subunit
3	0019843	molecular_function	rRNA binding
3	0022627	cellular_component	cytosolic small ribosomal subunit
3	0070181	molecular_function	small ribosomal subunit rRNA binding
3	1990904	cellular_component	ribonucleoprotein complex
A	0003723	molecular_function	RNA binding
A	0003743	molecular_function	translation initiation factor activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006413	biological_process	translational initiation
A	0009409	biological_process	response to cold
A	0016020	cellular_component	membrane
A	0032790	biological_process	ribosome disassembly
A	0043022	molecular_function	ribosome binding
h	0003676	molecular_function	nucleic acid binding
h	0003723	molecular_function	RNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0006412	biological_process	translation
j	0000028	biological_process	ribosomal small subunit assembly
j	0002181	biological_process	cytoplasmic translation
j	0003735	molecular_function	structural constituent of ribosome
j	0005515	molecular_function	protein binding
j	0005737	cellular_component	cytoplasm
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
j	0008270	molecular_function	zinc ion binding
j	0015935	cellular_component	small ribosomal subunit
j	0022627	cellular_component	cytosolic small ribosomal subunit
j	1990904	cellular_component	ribonucleoprotein complex
k	0000028	biological_process	ribosomal small subunit assembly
k	0002181	biological_process	cytoplasmic translation
k	0003723	molecular_function	RNA binding
k	0003735	molecular_function	structural constituent of ribosome
k	0005515	molecular_function	protein binding
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0015935	cellular_component	small ribosomal subunit
k	0019843	molecular_function	rRNA binding
k	0022627	cellular_component	cytosolic small ribosomal subunit
k	0046677	biological_process	response to antibiotic
k	1990145	biological_process	maintenance of translational fidelity
k	1990904	cellular_component	ribonucleoprotein complex
l	0000028	biological_process	ribosomal small subunit assembly
l	0000900	molecular_function	mRNA regulatory element binding translation repressor activity
l	0002181	biological_process	cytoplasmic translation
l	0003723	molecular_function	RNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0005515	molecular_function	protein binding
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0006353	biological_process	DNA-templated transcription termination
l	0006412	biological_process	translation
l	0006417	biological_process	regulation of translation
l	0015935	cellular_component	small ribosomal subunit
l	0019843	molecular_function	rRNA binding
l	0022627	cellular_component	cytosolic small ribosomal subunit
l	0031564	biological_process	transcription antitermination
l	0042254	biological_process	ribosome biogenesis
l	0042274	biological_process	ribosomal small subunit biogenesis
l	0045947	biological_process	negative regulation of translational initiation
l	0046677	biological_process	response to antibiotic
l	0048027	molecular_function	mRNA 5'-UTR binding
l	1990145	biological_process	maintenance of translational fidelity
l	1990904	cellular_component	ribonucleoprotein complex
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0006412	biological_process	translation
m	0015935	cellular_component	small ribosomal subunit
n	0003735	molecular_function	structural constituent of ribosome
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
n	0019843	molecular_function	rRNA binding
o	0000049	molecular_function	tRNA binding
o	0002181	biological_process	cytoplasmic translation
o	0003723	molecular_function	RNA binding
o	0003735	molecular_function	structural constituent of ribosome
o	0005737	cellular_component	cytoplasm
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0022627	cellular_component	cytosolic small ribosomal subunit
o	1990904	cellular_component	ribonucleoprotein complex
p	0000028	biological_process	ribosomal small subunit assembly
p	0002181	biological_process	cytoplasmic translation
p	0003735	molecular_function	structural constituent of ribosome
p	0005737	cellular_component	cytoplasm
p	0005829	cellular_component	cytosol
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
p	0006417	biological_process	regulation of translation
p	0019843	molecular_function	rRNA binding
p	0022627	cellular_component	cytosolic small ribosomal subunit
p	0043488	biological_process	regulation of mRNA stability
p	1990904	cellular_component	ribonucleoprotein complex
P	0000028	biological_process	ribosomal small subunit assembly
P	0002181	biological_process	cytoplasmic translation
P	0003735	molecular_function	structural constituent of ribosome
P	0005737	cellular_component	cytoplasm
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0008270	molecular_function	zinc ion binding
P	0019843	molecular_function	rRNA binding
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	0046677	biological_process	response to antibiotic
P	0070181	molecular_function	small ribosomal subunit rRNA binding
P	1990904	cellular_component	ribonucleoprotein complex
q	0002181	biological_process	cytoplasmic translation
q	0003735	molecular_function	structural constituent of ribosome
q	0005515	molecular_function	protein binding
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005840	cellular_component	ribosome
q	0006412	biological_process	translation
q	0019843	molecular_function	rRNA binding
q	0022627	cellular_component	cytosolic small ribosomal subunit
q	0070181	molecular_function	small ribosomal subunit rRNA binding
q	1990904	cellular_component	ribonucleoprotein complex
r	0000049	molecular_function	tRNA binding
r	0001072	molecular_function	transcription antitermination factor activity, RNA binding
r	0002181	biological_process	cytoplasmic translation
r	0003723	molecular_function	RNA binding
r	0003735	molecular_function	structural constituent of ribosome
r	0005515	molecular_function	protein binding
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	0008023	cellular_component	transcription elongation factor complex
r	0015935	cellular_component	small ribosomal subunit
r	0022627	cellular_component	cytosolic small ribosomal subunit
r	0031564	biological_process	transcription antitermination
r	0032784	biological_process	regulation of DNA-templated transcription elongation
r	0042254	biological_process	ribosome biogenesis
r	1990904	cellular_component	ribonucleoprotein complex
s	0000049	molecular_function	tRNA binding
s	0002181	biological_process	cytoplasmic translation
s	0003676	molecular_function	nucleic acid binding
s	0003723	molecular_function	RNA binding
s	0003735	molecular_function	structural constituent of ribosome
s	0005515	molecular_function	protein binding
s	0005737	cellular_component	cytoplasm
s	0005829	cellular_component	cytosol
s	0005840	cellular_component	ribosome
s	0006412	biological_process	translation
s	0015935	cellular_component	small ribosomal subunit
s	0019843	molecular_function	rRNA binding
s	0022627	cellular_component	cytosolic small ribosomal subunit
s	1990904	cellular_component	ribonucleoprotein complex
t	0000049	molecular_function	tRNA binding
t	0000372	biological_process	Group I intron splicing
t	0002181	biological_process	cytoplasmic translation
t	0003735	molecular_function	structural constituent of ribosome
t	0005515	molecular_function	protein binding
t	0005737	cellular_component	cytoplasm
t	0005829	cellular_component	cytosol
t	0005840	cellular_component	ribosome
t	0006412	biological_process	translation
t	0015935	cellular_component	small ribosomal subunit
t	0019843	molecular_function	rRNA binding
t	0022627	cellular_component	cytosolic small ribosomal subunit
t	0033120	biological_process	positive regulation of RNA splicing
t	0034336	molecular_function	misfolded RNA binding
t	0034337	biological_process	RNA folding
t	0046677	biological_process	response to antibiotic
t	1990145	biological_process	maintenance of translational fidelity
t	1990904	cellular_component	ribonucleoprotein complex
u	0000028	biological_process	ribosomal small subunit assembly
u	0002181	biological_process	cytoplasmic translation
u	0003735	molecular_function	structural constituent of ribosome
u	0005737	cellular_component	cytoplasm
u	0005829	cellular_component	cytosol
u	0005840	cellular_component	ribosome
u	0006412	biological_process	translation
u	0006417	biological_process	regulation of translation
u	0019843	molecular_function	rRNA binding
u	0022627	cellular_component	cytosolic small ribosomal subunit
u	0070181	molecular_function	small ribosomal subunit rRNA binding
u	1990904	cellular_component	ribonucleoprotein complex
w	0000028	biological_process	ribosomal small subunit assembly
w	0000049	molecular_function	tRNA binding
w	0002181	biological_process	cytoplasmic translation
w	0003735	molecular_function	structural constituent of ribosome
w	0005737	cellular_component	cytoplasm
w	0005840	cellular_component	ribosome
w	0006412	biological_process	translation
w	0015935	cellular_component	small ribosomal subunit
w	0019843	molecular_function	rRNA binding
w	0022627	cellular_component	cytosolic small ribosomal subunit
w	1990904	cellular_component	ribonucleoprotein complex
y	0000028	biological_process	ribosomal small subunit assembly
y	0000400	molecular_function	four-way junction DNA binding
y	0002181	biological_process	cytoplasmic translation
y	0003735	molecular_function	structural constituent of ribosome
y	0004519	molecular_function	endonuclease activity
y	0004520	molecular_function	DNA endonuclease activity
y	0005737	cellular_component	cytoplasm
y	0005840	cellular_component	ribosome
y	0006259	biological_process	DNA metabolic process
y	0006412	biological_process	translation
y	0015935	cellular_component	small ribosomal subunit
y	0022627	cellular_component	cytosolic small ribosomal subunit
y	1990904	cellular_component	ribonucleoprotein complex
z	0003723	molecular_function	RNA binding
z	0003735	molecular_function	structural constituent of ribosome
z	0005840	cellular_component	ribosome
z	0006412	biological_process	translation
z	0015935	cellular_component	small ribosomal subunit

Functional Information from PROSITE/UniProt

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. SeLlakFVnilmvdGKKstaesIVysA

Chain	Residue	Details
m	SER19-ALA45

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GiaVVSTSkGVMtdraAR

Chain	Residue	Details
p	GLY99-ARG116

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. IrALnaA.GFrItnitDvTPiPHN

Chain	Residue	Details
q	ILE96-ASN118

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR

Chain	Residue	Details
t	LYS42-ARG49

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIrEcRPLS

Chain	Residue	Details
P	GLY55-SER67

site_id	PS00057
Number of Residues	24
Details	RIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.IatLknYITEs.GKIvpsRI

Chain	Residue	Details
1	ILE20-ILE43

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. PdhkhavialTsiYGVGKTRSkAILaAAG

Chain	Residue	Details
s	PRO9-GLY37

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT

Chain	Residue	Details
z	ASN52-THR76

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGisGQagAirhGiTRAL

Chain	Residue	Details
o	GLY68-LEU86

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT

Chain	Residue	Details
r	ALA29-THR44

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. LqgHFaehKkDhhSrrgLlrMvsqrrkLldY

Chain	Residue	Details
u	LEU38-TYR68

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR

Chain	Residue	Details
w	ARG63-ARG85

site_id	PS00548
Number of Residues	35
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG

Chain	Residue	Details
h	ALA162-GLY196

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI

Chain	Residue	Details
k	GLY27-ILE59

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LEgRLdnvVYRmgfGaTraeARqLV

Chain	Residue	Details
l	LEU93-VAL117

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ

Chain	Residue	Details
s	ARG86-GLN99

site_id	PS00732
Number of Residues	10
Details	RIBOSOMAL_S16 Ribosomal protein S16 signature. VtIRLARHGA

Chain	Residue	Details
y	VAL2-ALA11

site_id	PS00938
Number of Residues	14
Details	IF3 Initiation factor 3 signature. RIMDYGKFlYEksK

Chain	Residue	Details
A	ARG66-LYS79

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. MrDMLKAGVHFG

Chain	Residue	Details
j	MET5-GLY16

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdaLFViDadhEhiaIkEannlGIP

Chain	Residue	Details
j	PRO157-PRO181

site_id	PS01048
Number of Residues	10
Details	RIBOSOMAL_S6 Ribosomal protein S6 signature. GrRQLAYpIN

Chain	Residue	Details
n	GLY43-ASN52

site_id	PS01181
Number of Residues	13
Details	RIBOSOMAL_S21 Ribosomal protein S21 signature. DvALRRFKRsceK

Chain	Residue	Details
2	ASP12-LYS24

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Important for 30S binding => ECO:0000305\|PubMed:1457399

Chain	Residue	Details
A	TYR107
A	LYS110

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-methylmethionine; in Translation initiation factor IF-3; alternate => ECO:0000269\|PubMed:330233

Chain	Residue	Details
A	MET1

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)