8JSC
Structure of the FSP1 protein from Human
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004174 | molecular_function | electron-transferring-flavoprotein dehydrogenase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005615 | cellular_component | extracellular space |
| C | 0005634 | cellular_component | nucleus |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005741 | cellular_component | mitochondrial outer membrane |
| C | 0005811 | cellular_component | lipid droplet |
| C | 0005829 | cellular_component | cytosol |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006743 | biological_process | ubiquinone metabolic process |
| C | 0008637 | biological_process | apoptotic mitochondrial changes |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016655 | molecular_function | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor |
| C | 0022904 | biological_process | respiratory electron transport chain |
| C | 0031966 | cellular_component | mitochondrial membrane |
| C | 0042373 | biological_process | vitamin K metabolic process |
| C | 0043065 | biological_process | positive regulation of apoptotic process |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0110076 | biological_process | negative regulation of ferroptosis |
| C | 1900407 | biological_process | regulation of cellular response to oxidative stress |
| C | 1990748 | biological_process | cellular detoxification |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37739993","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38414669","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39160155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8WIK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YO8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YOQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YOX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37739993","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37739993","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39160155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YO8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YOQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YOX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38414669","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39160155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8WIK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YO8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YOQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YOX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37739993","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38414669","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JSC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8WIK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38414669","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8WIK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39160155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8YOQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"39160155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8YO8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38414669","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39160155","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8WIK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8YOQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Site: {"description":"4-hydroxy-2-nonenal adduction","evidences":[{"source":"UniProtKB","id":"Q8BUE4","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine; by KAT2B","evidences":[{"source":"PubMed","id":"39881208","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
