8JPS

Structure of Duffy Antigen Receptor for Chemokines (DARC)/ACKR1 in complex with the chemokine, CCL7 (Composite map)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006954	biological_process	inflammatory response
A	0016020	cellular_component	membrane
A	0019956	molecular_function	chemokine binding
A	0070098	biological_process	chemokine-mediated signaling pathway
B	0006954	biological_process	inflammatory response
B	0016020	cellular_component	membrane
B	0019956	molecular_function	chemokine binding
B	0070098	biological_process	chemokine-mediated signaling pathway
C	0005576	cellular_component	extracellular region
C	0006955	biological_process	immune response
C	0008009	molecular_function	chemokine activity
D	0005576	cellular_component	extracellular region
D	0006955	biological_process	immune response
D	0008009	molecular_function	chemokine activity

Functional Information from PROSITE/UniProt

site_id	PS00472
Number of Residues	43
Details	SMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCYrfinkk..IpkqrLesYrrttssh.Cpre.AVIFktkldkei.CA

Chain	Residue	Details
D	CYS11-ALA53

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	44
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	104
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	46
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	40
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---