8JP9

Cryo-EM structure of the head region of full-length ERGIC-53 with MCFD2 (Substate D)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
B	0016020	cellular_component	membrane
C	0005509	molecular_function	calcium ion binding
C	0005515	molecular_function	protein binding
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005793	cellular_component	endoplasmic reticulum-Golgi intermediate compartment
C	0005794	cellular_component	Golgi apparatus
C	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
C	0012507	cellular_component	ER to Golgi transport vesicle membrane
C	0015031	biological_process	protein transport
C	0016192	biological_process	vesicle-mediated transport
C	0033116	cellular_component	endoplasmic reticulum-Golgi intermediate compartment membrane
C	0046872	molecular_function	metal ion binding
D	0005509	molecular_function	calcium ion binding
D	0005515	molecular_function	protein binding
D	0005783	cellular_component	endoplasmic reticulum
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0005793	cellular_component	endoplasmic reticulum-Golgi intermediate compartment
D	0005794	cellular_component	Golgi apparatus
D	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
D	0012507	cellular_component	ER to Golgi transport vesicle membrane
D	0015031	biological_process	protein transport
D	0016192	biological_process	vesicle-mediated transport
D	0033116	cellular_component	endoplasmic reticulum-Golgi intermediate compartment membrane
D	0046872	molecular_function	metal ion binding
E	0016020	cellular_component	membrane
F	0016020	cellular_component	membrane
G	0005509	molecular_function	calcium ion binding
G	0005515	molecular_function	protein binding
G	0005783	cellular_component	endoplasmic reticulum
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0005793	cellular_component	endoplasmic reticulum-Golgi intermediate compartment
G	0005794	cellular_component	Golgi apparatus
G	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
G	0012507	cellular_component	ER to Golgi transport vesicle membrane
G	0015031	biological_process	protein transport
G	0016192	biological_process	vesicle-mediated transport
G	0033116	cellular_component	endoplasmic reticulum-Golgi intermediate compartment membrane
G	0046872	molecular_function	metal ion binding
H	0005509	molecular_function	calcium ion binding
H	0005515	molecular_function	protein binding
H	0005783	cellular_component	endoplasmic reticulum
H	0005789	cellular_component	endoplasmic reticulum membrane
H	0005793	cellular_component	endoplasmic reticulum-Golgi intermediate compartment
H	0005794	cellular_component	Golgi apparatus
H	0006888	biological_process	endoplasmic reticulum to Golgi vesicle-mediated transport
H	0012507	cellular_component	ER to Golgi transport vesicle membrane
H	0015031	biological_process	protein transport
H	0016192	biological_process	vesicle-mediated transport
H	0033116	cellular_component	endoplasmic reticulum-Golgi intermediate compartment membrane
H	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DYDGNNLLDglEL

Chain	Residue	Details
C	ASP81-LEU93
C	ASP129-PHE141

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	892
Details	Domain: {"description":"L-type lectin-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00658","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00658","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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