8JMI
The cryo-EM structure of insect gustatory receptor Gr64a from Drosophila melanogaster in complex with maltose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001582 | biological_process | detection of chemical stimulus involved in sensory perception of sweet taste |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007165 | biological_process | signal transduction |
| A | 0007637 | biological_process | proboscis extension reflex |
| A | 0008527 | molecular_function | taste receptor activity |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0033041 | molecular_function | sweet taste receptor activity |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0050909 | biological_process | sensory perception of taste |
| A | 0050912 | biological_process | detection of chemical stimulus involved in sensory perception of taste |
| A | 0050916 | biological_process | sensory perception of sweet taste |
| A | 0170023 | molecular_function | ionotropic sweet taste receptor activity |
| B | 0001582 | biological_process | detection of chemical stimulus involved in sensory perception of sweet taste |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007165 | biological_process | signal transduction |
| B | 0007637 | biological_process | proboscis extension reflex |
| B | 0008527 | molecular_function | taste receptor activity |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0033041 | molecular_function | sweet taste receptor activity |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0050909 | biological_process | sensory perception of taste |
| B | 0050912 | biological_process | detection of chemical stimulus involved in sensory perception of taste |
| B | 0050916 | biological_process | sensory perception of sweet taste |
| B | 0170023 | molecular_function | ionotropic sweet taste receptor activity |
| C | 0001582 | biological_process | detection of chemical stimulus involved in sensory perception of sweet taste |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0007165 | biological_process | signal transduction |
| C | 0007637 | biological_process | proboscis extension reflex |
| C | 0008527 | molecular_function | taste receptor activity |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| C | 0033041 | molecular_function | sweet taste receptor activity |
| C | 0034220 | biological_process | monoatomic ion transmembrane transport |
| C | 0050909 | biological_process | sensory perception of taste |
| C | 0050912 | biological_process | detection of chemical stimulus involved in sensory perception of taste |
| C | 0050916 | biological_process | sensory perception of sweet taste |
| C | 0170023 | molecular_function | ionotropic sweet taste receptor activity |
| D | 0001582 | biological_process | detection of chemical stimulus involved in sensory perception of sweet taste |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0007165 | biological_process | signal transduction |
| D | 0007637 | biological_process | proboscis extension reflex |
| D | 0008527 | molecular_function | taste receptor activity |
| D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
| D | 0033041 | molecular_function | sweet taste receptor activity |
| D | 0034220 | biological_process | monoatomic ion transmembrane transport |
| D | 0050909 | biological_process | sensory perception of taste |
| D | 0050912 | biological_process | detection of chemical stimulus involved in sensory perception of taste |
| D | 0050916 | biological_process | sensory perception of sweet taste |
| D | 0170023 | molecular_function | ionotropic sweet taste receptor activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 88 |
| Details | Transmembrane: {"description":"Helical; Name=S1","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 292 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 84 |
| Details | Transmembrane: {"description":"Helical; Name=S2","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 496 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 88 |
| Details | Transmembrane: {"description":"Helical; Name=S3","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 100 |
| Details | Transmembrane: {"description":"Helical; Name=S4","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 92 |
| Details | Transmembrane: {"description":"Helical; Name=S5","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 88 |
| Details | Transmembrane: {"description":"Helical; Name=S6","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 76 |
| Details | Transmembrane: {"description":"Helical; Name=S7b","evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JME","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JMH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38305684","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8JMI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
