8JL4

membrane proteins

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005764	cellular_component	lysosome
A	0005765	cellular_component	lysosomal membrane
A	0005886	cellular_component	plasma membrane
A	0007041	biological_process	lysosomal transport
A	0015019	molecular_function	heparan-alpha-glucosaminide N-acetyltransferase activity
A	0016020	cellular_component	membrane
A	0016746	molecular_function	acyltransferase activity
A	0030200	biological_process	heparan sulfate proteoglycan catabolic process
A	0035579	cellular_component	specific granule membrane
A	0043202	cellular_component	lysosomal lumen
A	0051259	biological_process	protein complex oligomerization
A	0070821	cellular_component	tertiary granule membrane
B	0005764	cellular_component	lysosome
B	0005765	cellular_component	lysosomal membrane
B	0005886	cellular_component	plasma membrane
B	0007041	biological_process	lysosomal transport
B	0015019	molecular_function	heparan-alpha-glucosaminide N-acetyltransferase activity
B	0016020	cellular_component	membrane
B	0016746	molecular_function	acyltransferase activity
B	0030200	biological_process	heparan sulfate proteoglycan catabolic process
B	0035579	cellular_component	specific granule membrane
B	0043202	cellular_component	lysosomal lumen
B	0051259	biological_process	protein complex oligomerization
B	0070821	cellular_component	tertiary granule membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	584
Details	TOPO_DOM: Lumenal, vesicle => ECO:0000255

Chain	Residue	Details
A	MET1-SER190
B	GLY442-GLY500
B	LYS551-ASN564
B	HIS614-LYS634
A	HIS297-GLY302
A	SER367-PRO374
A	GLY442-GLY500
A	LYS551-ASN564
A	HIS614-LYS634
B	MET1-SER190
B	HIS297-GLY302
B	SER367-PRO374

---

site_id	SWS_FT_FI2
Number of Residues	440
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	ASN191-LEU211
A	GLY593-GLY613
A	GLU635-TYR655
B	ASN191-LEU211
B	GLY276-LYS296
B	LEU303-LEU323
B	SER346-LEU366
B	GLY375-ALA395
B	TRP421-PRO441
B	ILE501-LEU521
B	ASP530-THR550
A	GLY276-LYS296
B	LEU565-LEU585
B	GLY593-GLY613
B	GLU635-TYR655
A	LEU303-LEU323
A	SER346-LEU366
A	GLY375-ALA395
A	TRP421-PRO441
A	ILE501-LEU521
A	ASP530-THR550
A	LEU565-LEU585

---

site_id	SWS_FT_FI3
Number of Residues	256
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	ARG212-ARG275
B	LEU522-LYS529
B	TYR586-LYS592
B	ARG656-ILE663
A	SER324-ARG345
A	LYS396-GLN420
A	LEU522-LYS529
A	TYR586-LYS592
A	ARG656-ILE663
B	ARG212-ARG275
B	SER324-ARG345
B	LYS396-GLN420

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:20650889

Chain	Residue	Details
A	HIS297
B	HIS297

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER243
B	SER243

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER245
B	SER245

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN94
A	ASN162
B	ASN94
B	ASN162

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218

Chain	Residue	Details
A	ASN142
B	ASN142

---