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8JKS

T95R mutant IRF4 DNA-binding domain bound to an DNA containing GAGA motif

Functional Information from GO Data
ChainGOidnamespacecontents
C0000976molecular_functiontranscription cis-regulatory region binding
C0003700molecular_functionDNA-binding transcription factor activity
C0006355biological_processregulation of DNA-templated transcription
D0000976molecular_functiontranscription cis-regulatory region binding
D0003700molecular_functionDNA-binding transcription factor activity
D0006355biological_processregulation of DNA-templated transcription
G0000976molecular_functiontranscription cis-regulatory region binding
G0003700molecular_functionDNA-binding transcription factor activity
G0006355biological_processregulation of DNA-templated transcription
H0000976molecular_functiontranscription cis-regulatory region binding
H0003700molecular_functionDNA-binding transcription factor activity
H0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00601
Number of Residues34
DetailsIRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WeNeeksiFrIPWkHagkqdynreeDaaLFKaWA
ChainResidueDetails
CTRP42-ALA75

227561

PDB entries from 2024-11-20

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