Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8JKE

AfsR(T337A) transcription activation complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
A	0005737	cellular_component	cytoplasm
A	0006351	biological_process	DNA-templated transcription
A	0009295	cellular_component	nucleoid
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0046983	molecular_function	protein dimerization activity
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
B	0005737	cellular_component	cytoplasm
B	0006351	biological_process	DNA-templated transcription
B	0009295	cellular_component	nucleoid
B	0016779	molecular_function	nucleotidyltransferase activity
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0046983	molecular_function	protein dimerization activity
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
C	0006351	biological_process	DNA-templated transcription
C	0016779	molecular_function	nucleotidyltransferase activity
C	0032549	molecular_function	ribonucleoside binding
C	0034062	molecular_function	5'-3' RNA polymerase activity
D	0000287	molecular_function	magnesium ion binding
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0003677	molecular_function	DNA binding
D	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
D	0006351	biological_process	DNA-templated transcription
D	0008270	molecular_function	zinc ion binding
D	0016779	molecular_function	nucleotidyltransferase activity
D	0034062	molecular_function	5'-3' RNA polymerase activity
D	0046872	molecular_function	metal ion binding
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0016779	molecular_function	nucleotidyltransferase activity
E	0034062	molecular_function	5'-3' RNA polymerase activity
F	0001108	molecular_function	bacterial-type RNA polymerase holo enzyme binding
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0005515	molecular_function	protein binding
F	0005737	cellular_component	cytoplasm
F	0006352	biological_process	DNA-templated transcription initiation
F	0006355	biological_process	regulation of DNA-templated transcription
F	0010468	biological_process	regulation of gene expression
F	0016987	molecular_function	sigma factor activity
F	2000142	biological_process	regulation of DNA-templated transcription initiation
G	0001000	molecular_function	bacterial-type RNA polymerase core enzyme binding
G	0001108	molecular_function	bacterial-type RNA polymerase holo enzyme binding
G	0005515	molecular_function	protein binding
G	0008270	molecular_function	zinc ion binding
G	0045893	biological_process	positive regulation of DNA-templated transcription
G	0046677	biological_process	response to antibiotic
G	0046872	molecular_function	metal ion binding
H	0009303	biological_process	rRNA transcription
I	0000160	biological_process	phosphorelay signal transduction system
I	0003677	molecular_function	DNA binding
I	0005524	molecular_function	ATP binding
I	0006355	biological_process	regulation of DNA-templated transcription
I	0017000	biological_process	antibiotic biosynthetic process
I	0031409	molecular_function	pigment binding
I	0043531	molecular_function	ADP binding
J	0000160	biological_process	phosphorelay signal transduction system
J	0003677	molecular_function	DNA binding
J	0005524	molecular_function	ATP binding
J	0006355	biological_process	regulation of DNA-templated transcription
J	0017000	biological_process	antibiotic biosynthetic process
J	0031409	molecular_function	pigment binding
J	0043531	molecular_function	ADP binding
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed 5'-3' RNA polymerase activity
K	0005737	cellular_component	cytoplasm
K	0006351	biological_process	DNA-templated transcription
K	0009295	cellular_component	nucleoid
K	0016779	molecular_function	nucleotidyltransferase activity
K	0034062	molecular_function	5'-3' RNA polymerase activity
K	0046983	molecular_function	protein dimerization activity

Functional Information from PROSITE/UniProt

site_id	PS00715
Number of Residues	14
Details	SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnLGLIrAV

Chain	Residue	Details
F	ASP302-VAL315

site_id	PS00716
Number of Residues	27
Details	SIGMA70_2 Sigma-70 factors family signature 2. TldEIGkvygVTrerIrQIEsktMskL

Chain	Residue	Details
F	THR471-LEU497

site_id	PS00867
Number of Residues	8
Details	CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LLEANLRL

Chain	Residue	Details
F	LEU278-LEU285

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKLAGrHGNKGV

Chain	Residue	Details
C	GLY868-VAL880

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
G	CYS34
D	CYS969
D	CYS972
G	CYS56
G	CYS59
D	CYS78
D	ASP535
D	ASP537
D	ASP539
D	CYS886
D	CYS962

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01483

Chain	Residue	Details
G	HIS38
I	GLN974-ALA988
J	GLN796-ALA811
J	GLN974-ALA988

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
I	GLY330
J	GLY330

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)