8JKD
Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0019049 | biological_process | virus-mediated perturbation of host defense response |
| A | 0044423 | cellular_component | virion component |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0019049 | biological_process | virus-mediated perturbation of host defense response |
| B | 0044423 | cellular_component | virion component |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0019049 | biological_process | virus-mediated perturbation of host defense response |
| C | 0044423 | cellular_component | virion component |
Functional Information from PROSITE/UniProt
| site_id | PS00028 |
| Number of Residues | 23 |
| Details | ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Ctgd.CperCgctsstclHkewp.H |
| Chain | Residue | Details |
| A | CYS1165-HIS1187 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 21 |
| Details | SITE: Involved in fusion with the host membrane => ECO:0000269|PubMed:34793197 |
| Chain | Residue | Details |
| A | TRP1068 | |
| B | TRP1197 | |
| B | TRP1199 | |
| B | MET1362 | |
| B | TRP1365 | |
| B | HIS1479 | |
| C | TRP1068 | |
| C | TRP1191 | |
| C | TRP1197 | |
| C | TRP1199 | |
| C | MET1362 | |
| A | TRP1191 | |
| C | TRP1365 | |
| C | HIS1479 | |
| A | TRP1197 | |
| A | TRP1199 | |
| A | MET1362 | |
| A | TRP1365 | |
| A | HIS1479 | |
| B | TRP1068 | |
| B | TRP1191 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000269|PubMed:17197010 |
| Chain | Residue | Details |
| A | ASN1054 | |
| A | ASN1563 | |
| B | ASN1054 | |
| B | ASN1563 | |
| C | ASN1054 | |
| C | ASN1563 |
