8JGJ
Cryo-EM structure of mClC-3 with ATP
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 634 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:P35523 |
| Chain | Residue | Details |
| A | MET1-ALA125 | |
| A | GLY625-ASN818 | |
| B | MET1-ALA125 | |
| B | GLY625-ASN818 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 434 |
| Details | TRANSMEM: Helical => ECO:0000250|UniProtKB:P35523 |
| Chain | Residue | Details |
| A | TRP126-SER163 | |
| A | TYR606-PHE624 | |
| B | TRP126-SER163 | |
| B | MET209-PHE232 | |
| B | GLY258-GLY276 | |
| B | GLU282-PRO301 | |
| B | LEU349-ASN367 | |
| B | PHE391-ARG416 | |
| B | PHE423-PHE443 | |
| B | ILE500-ILE520 | |
| B | GLY525-ALA544 | |
| A | MET209-PHE232 | |
| B | TYR606-PHE624 | |
| A | GLY258-GLY276 | |
| A | GLU282-PRO301 | |
| A | LEU349-ASN367 | |
| A | PHE391-ARG416 | |
| A | PHE423-PHE443 | |
| A | ILE500-ILE520 | |
| A | GLY525-ALA544 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 104 |
| Details | INTRAMEM: Helical => ECO:0000250|UniProtKB:P35523 |
| Chain | Residue | Details |
| A | ILE241-LEU248 | |
| B | THR590-THR601 | |
| A | VAL313-ALA325 | |
| A | PRO329-LEU337 | |
| A | GLY572-VAL586 | |
| A | THR590-THR601 | |
| B | ILE241-LEU248 | |
| B | VAL313-ALA325 | |
| B | PRO329-LEU337 | |
| B | GLY572-VAL586 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | INTRAMEM: Note=Loop between two helices => ECO:0000250|UniProtKB:P35523 |
| Chain | Residue | Details |
| A | GLY602-GLU605 | |
| B | GLY602-GLU605 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER239 | |
| B | THR796 | |
| A | PHE527 | |
| A | TYR630 | |
| A | TYR689 | |
| A | THR796 | |
| B | SER239 | |
| B | PHE527 | |
| B | TYR630 | |
| B | TYR689 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Mediates proton transfer from the outer aqueous phase to the interior of the protein; involved in linking H(+) and Cl(-) transport => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU282 | |
| B | GLU282 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | SITE: Mediates proton transfer from the protein to the inner aqueous phase => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU339 | |
| B | GLU339 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN177 | |
| A | ASN451 | |
| A | ASN479 | |
| B | ASN177 | |
| B | ASN451 | |
| B | ASN479 |
