8JF0

Human sodium-dependent vitamin C transporter 1 in an intermediate state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0006814	biological_process	sodium ion transport
A	0007420	biological_process	brain development
A	0008520	molecular_function	L-ascorbate:sodium symporter activity
A	0009636	biological_process	response to toxic substance
A	0009925	cellular_component	basal plasma membrane
A	0015081	molecular_function	sodium ion transmembrane transporter activity
A	0015143	molecular_function	urate transmembrane transporter activity
A	0015205	molecular_function	nucleobase transmembrane transporter activity
A	0015229	molecular_function	L-ascorbic acid transmembrane transporter activity
A	0015293	molecular_function	symporter activity
A	0015747	biological_process	urate transport
A	0015851	biological_process	nucleobase transport
A	0015882	biological_process	L-ascorbic acid transmembrane transport
A	0016020	cellular_component	membrane
A	0016324	cellular_component	apical plasma membrane
A	0019852	biological_process	L-ascorbic acid metabolic process
A	0022857	molecular_function	transmembrane transporter activity
A	0030324	biological_process	lung development
A	0033300	molecular_function	dehydroascorbic acid transmembrane transporter activity
A	0035725	biological_process	sodium ion transmembrane transport
A	0043229	cellular_component	intracellular organelle
A	0055085	biological_process	transmembrane transport
A	0070062	cellular_component	extracellular exosome
A	0070837	biological_process	dehydroascorbic acid transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	217
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	57
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	76
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19379732","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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