8J9Z

cryo-EM structure of viral topoisomerase in conformation 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000819	biological_process	sister chromatid segregation
A	0003677	molecular_function	DNA binding
A	0003916	molecular_function	DNA topoisomerase activity
A	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0006259	biological_process	DNA metabolic process
A	0006265	biological_process	DNA topological change
A	0016853	molecular_function	isomerase activity
A	0030430	cellular_component	host cell cytoplasm
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0000819	biological_process	sister chromatid segregation
B	0003677	molecular_function	DNA binding
B	0003916	molecular_function	DNA topoisomerase activity
B	0003918	molecular_function	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
B	0005524	molecular_function	ATP binding
B	0006259	biological_process	DNA metabolic process
B	0006265	biological_process	DNA topological change
B	0016853	molecular_function	isomerase activity
B	0030430	cellular_component	host cell cytoplasm
B	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00177
Number of Residues	9
Details	TOPOISOMERASE_II DNA topoisomerase II signature. AAEGDSALS

Chain	Residue	Details
A	ALA436-SER444

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