8J6O
transport T2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000902 | biological_process | cell morphogenesis |
| A | 0003323 | biological_process | type B pancreatic cell development |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003725 | molecular_function | double-stranded RNA binding |
| A | 0005764 | cellular_component | lysosome |
| A | 0005765 | cellular_component | lysosomal membrane |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006401 | biological_process | RNA catabolic process |
| A | 0008218 | biological_process | bioluminescence |
| A | 0009749 | biological_process | response to glucose |
| A | 0035612 | molecular_function | AP-2 adaptor complex binding |
| A | 0035650 | molecular_function | AP-1 adaptor complex binding |
| A | 0042593 | biological_process | glucose homeostasis |
| A | 0044342 | biological_process | type B pancreatic cell proliferation |
| A | 0050658 | biological_process | RNA transport |
| A | 0051032 | molecular_function | nucleic acid transmembrane transporter activity |
| A | 0051033 | molecular_function | RNA transmembrane transporter activity |
| A | 0061178 | biological_process | regulation of insulin secretion involved in cellular response to glucose stimulus |
| B | 0000902 | biological_process | cell morphogenesis |
| B | 0003323 | biological_process | type B pancreatic cell development |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003725 | molecular_function | double-stranded RNA binding |
| B | 0005764 | cellular_component | lysosome |
| B | 0005765 | cellular_component | lysosomal membrane |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006401 | biological_process | RNA catabolic process |
| B | 0008218 | biological_process | bioluminescence |
| B | 0009749 | biological_process | response to glucose |
| B | 0035612 | molecular_function | AP-2 adaptor complex binding |
| B | 0035650 | molecular_function | AP-1 adaptor complex binding |
| B | 0042593 | biological_process | glucose homeostasis |
| B | 0044342 | biological_process | type B pancreatic cell proliferation |
| B | 0050658 | biological_process | RNA transport |
| B | 0051032 | molecular_function | nucleic acid transmembrane transporter activity |
| B | 0051033 | molecular_function | RNA transmembrane transporter activity |
| B | 0061178 | biological_process | regulation of insulin secretion involved in cellular response to glucose stimulus |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 804 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | HIS19-GLY296 | |
| B | TYR653-ARG688 | |
| B | LYS737-LEU746 | |
| B | ASP818-PHE832 | |
| A | ILE469-ALA499 | |
| A | HIS568-SER605 | |
| A | TYR653-ARG688 | |
| A | LYS737-LEU746 | |
| A | ASP818-PHE832 | |
| B | HIS19-GLY296 | |
| B | ILE469-ALA499 | |
| B | HIS568-SER605 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 400 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | MET297-TRP317 | |
| A | ASP797-LEU817 | |
| B | MET297-TRP317 | |
| B | ILE448-VAL468 | |
| B | PHE500-ILE520 | |
| B | PHE547-TYR567 | |
| B | ALA606-PHE626 | |
| B | ALA632-LEU652 | |
| B | MET689-MET709 | |
| B | SER716-MET736 | |
| B | ILE747-PHE767 | |
| A | ILE448-VAL468 | |
| B | ASP797-LEU817 | |
| A | PHE500-ILE520 | |
| A | PHE547-TYR567 | |
| A | ALA606-PHE626 | |
| A | ALA632-LEU652 | |
| A | MET689-MET709 | |
| A | SER716-MET736 | |
| A | ILE747-PHE767 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 382 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | GLU318-GLN447 | |
| B | GLN768-HIS796 | |
| A | LEU521-HIS546 | |
| A | GLY627-THR631 | |
| A | ARG710-ALA715 | |
| A | GLN768-HIS796 | |
| B | GLU318-GLN447 | |
| B | LEU521-HIS546 | |
| B | GLY627-THR631 | |
| B | ARG710-ALA715 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648 |
| Chain | Residue | Details |
| A | SER401 | |
| A | SER403 | |
| A | SER404 | |
| B | SER401 | |
| B | SER403 | |
| B | SER404 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN27 | |
| A | ASN603 | |
| B | ASN27 | |
| B | ASN54 | |
| B | ASN60 | |
| B | ASN123 | |
| B | ASN141 | |
| B | ASN165 | |
| B | ASN476 | |
| B | ASN496 | |
| B | ASN572 | |
| A | ASN54 | |
| B | ASN603 | |
| A | ASN60 | |
| A | ASN123 | |
| A | ASN141 | |
| A | ASN165 | |
| A | ASN476 | |
| A | ASN496 | |
| A | ASN572 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: (Z)-2,3-didehydrotyrosine => ECO:0000269|PubMed:8448132 |
| Chain | Residue | Details |
| A | TYR-159 | |
| B | TYR-159 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | CROSSLNK: 5-imidazolinone (Ser-Gly) => ECO:0000269|PubMed:8448132 |
| Chain | Residue | Details |
| A | THR-160 | |
| A | GLY-158 | |
| B | THR-160 | |
| B | GLY-158 |
