8J4Y

Structure of Mycobacterium tuberculosis NrdF2:NrdIcomplex (reduced) determined at 3 angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
A	0005515	molecular_function	protein binding
A	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
A	0006260	biological_process	DNA replication
A	0009263	biological_process	deoxyribonucleotide biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
B	0005515	molecular_function	protein binding
B	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
B	0006260	biological_process	DNA replication
B	0009263	biological_process	deoxyribonucleotide biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
C	0005515	molecular_function	protein binding
C	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
C	0006260	biological_process	DNA replication
C	0009263	biological_process	deoxyribonucleotide biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
D	0005515	molecular_function	protein binding
D	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
D	0006260	biological_process	DNA replication
D	0009263	biological_process	deoxyribonucleotide biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
E	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
E	0005515	molecular_function	protein binding
E	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
E	0006260	biological_process	DNA replication
E	0009263	biological_process	deoxyribonucleotide biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
F	0004748	molecular_function	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
F	0005515	molecular_function	protein binding
F	0005971	cellular_component	ribonucleoside-diphosphate reductase complex
F	0006260	biological_process	DNA replication
F	0009263	biological_process	deoxyribonucleotide biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
G	0010181	molecular_function	FMN binding
I	0010181	molecular_function	FMN binding

Functional Information from PROSITE/UniProt

site_id	PS00368
Number of Residues	17
Details	RIBORED_SMALL Ribonucleotide reductase small subunit signature. MEs.VHAkSYsqIfstLC

Chain	Residue	Details
A	MET102-CYS118

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE:

Chain	Residue	Details
A	TYR110
B	TYR110
C	TYR110
D	TYR110
E	TYR110
F	TYR110

---

site_id	SWS_FT_FI2
Number of Residues	30
Details	BINDING:

Chain	Residue	Details
A	GLU103
B	HIS200
C	GLU103
C	HIS106
C	GLU163
C	GLU197
C	HIS200
D	GLU103
D	HIS106
D	GLU163
D	GLU197
A	HIS106
D	HIS200
E	GLU103
E	HIS106
E	GLU163
E	GLU197
E	HIS200
F	GLU103
F	HIS106
F	GLU163
F	GLU197
A	GLU163
F	HIS200
A	GLU197
A	HIS200
B	GLU103
B	HIS106
B	GLU163
B	GLU197

---