8J03

Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state I

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0005249	molecular_function	voltage-gated potassium channel activity
A	0006811	biological_process	monoatomic ion transport
A	0006813	biological_process	potassium ion transport
A	0016020	cellular_component	membrane
A	0055085	biological_process	transmembrane transport
D	0005216	molecular_function	monoatomic ion channel activity
D	0005249	molecular_function	voltage-gated potassium channel activity
D	0006811	biological_process	monoatomic ion transport
D	0006813	biological_process	potassium ion transport
D	0016020	cellular_component	membrane
D	0055085	biological_process	transmembrane transport
E	0000086	biological_process	G2/M transition of mitotic cell cycle
E	0000922	cellular_component	spindle pole
E	0002027	biological_process	regulation of heart rate
E	0005246	molecular_function	calcium channel regulator activity
E	0005509	molecular_function	calcium ion binding
E	0005513	biological_process	detection of calcium ion
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005819	cellular_component	spindle
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0005876	cellular_component	spindle microtubule
E	0005886	cellular_component	plasma membrane
E	0005929	cellular_component	cilium
E	0007186	biological_process	G protein-coupled receptor signaling pathway
E	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
E	0008076	cellular_component	voltage-gated potassium channel complex
E	0010856	molecular_function	adenylate cyclase activator activity
E	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
E	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
E	0016020	cellular_component	membrane
E	0016240	biological_process	autophagosome membrane docking
E	0019855	molecular_function	calcium channel inhibitor activity
E	0019901	molecular_function	protein kinase binding
E	0021762	biological_process	substantia nigra development
E	0030017	cellular_component	sarcomere
E	0030672	cellular_component	synaptic vesicle membrane
E	0031432	molecular_function	titin binding
E	0031514	cellular_component	motile cilium
E	0031982	cellular_component	vesicle
E	0032465	biological_process	regulation of cytokinesis
E	0032991	cellular_component	protein-containing complex
E	0034704	cellular_component	calcium channel complex
E	0035458	biological_process	cellular response to interferon-beta
E	0042995	cellular_component	cell projection
E	0043209	cellular_component	myelin sheath
E	0043539	molecular_function	protein serine/threonine kinase activator activity
E	0044305	cellular_component	calyx of Held
E	0044325	molecular_function	transmembrane transporter binding
E	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
E	0046872	molecular_function	metal ion binding
E	0048306	molecular_function	calcium-dependent protein binding
E	0050848	biological_process	regulation of calcium-mediated signaling
E	0051592	biological_process	response to calcium ion
E	0055117	biological_process	regulation of cardiac muscle contraction
E	0060291	biological_process	long-term synaptic potentiation
E	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
E	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
E	0071346	biological_process	cellular response to type II interferon
E	0072542	molecular_function	protein phosphatase activator activity
E	0097225	cellular_component	sperm midpiece
E	0097720	biological_process	calcineurin-mediated signaling
E	0098901	biological_process	regulation of cardiac muscle cell action potential
E	0099523	cellular_component	presynaptic cytosol
E	0140056	biological_process	organelle localization by membrane tethering
E	0140238	biological_process	presynaptic endocytosis
E	0141110	molecular_function	transporter inhibitor activity
E	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
E	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
E	1902494	cellular_component	catalytic complex
E	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
E	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
F	0000086	biological_process	G2/M transition of mitotic cell cycle
F	0000922	cellular_component	spindle pole
F	0002027	biological_process	regulation of heart rate
F	0005246	molecular_function	calcium channel regulator activity
F	0005509	molecular_function	calcium ion binding
F	0005513	biological_process	detection of calcium ion
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005813	cellular_component	centrosome
F	0005819	cellular_component	spindle
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0005876	cellular_component	spindle microtubule
F	0005886	cellular_component	plasma membrane
F	0005929	cellular_component	cilium
F	0007186	biological_process	G protein-coupled receptor signaling pathway
F	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
F	0008076	cellular_component	voltage-gated potassium channel complex
F	0010856	molecular_function	adenylate cyclase activator activity
F	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
F	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
F	0016020	cellular_component	membrane
F	0016240	biological_process	autophagosome membrane docking
F	0019855	molecular_function	calcium channel inhibitor activity
F	0019901	molecular_function	protein kinase binding
F	0021762	biological_process	substantia nigra development
F	0030017	cellular_component	sarcomere
F	0030672	cellular_component	synaptic vesicle membrane
F	0031432	molecular_function	titin binding
F	0031514	cellular_component	motile cilium
F	0031982	cellular_component	vesicle
F	0032465	biological_process	regulation of cytokinesis
F	0032991	cellular_component	protein-containing complex
F	0034704	cellular_component	calcium channel complex
F	0035458	biological_process	cellular response to interferon-beta
F	0042995	cellular_component	cell projection
F	0043209	cellular_component	myelin sheath
F	0043539	molecular_function	protein serine/threonine kinase activator activity
F	0044305	cellular_component	calyx of Held
F	0044325	molecular_function	transmembrane transporter binding
F	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
F	0046872	molecular_function	metal ion binding
F	0048306	molecular_function	calcium-dependent protein binding
F	0050848	biological_process	regulation of calcium-mediated signaling
F	0051592	biological_process	response to calcium ion
F	0055117	biological_process	regulation of cardiac muscle contraction
F	0060291	biological_process	long-term synaptic potentiation
F	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
F	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
F	0071346	biological_process	cellular response to type II interferon
F	0072542	molecular_function	protein phosphatase activator activity
F	0097225	cellular_component	sperm midpiece
F	0097720	biological_process	calcineurin-mediated signaling
F	0098901	biological_process	regulation of cardiac muscle cell action potential
F	0099523	cellular_component	presynaptic cytosol
F	0140056	biological_process	organelle localization by membrane tethering
F	0140238	biological_process	presynaptic endocytosis
F	0141110	molecular_function	transporter inhibitor activity
F	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
F	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
F	1902494	cellular_component	catalytic complex
F	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
F	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
G	0005216	molecular_function	monoatomic ion channel activity
G	0005249	molecular_function	voltage-gated potassium channel activity
G	0006811	biological_process	monoatomic ion transport
G	0006813	biological_process	potassium ion transport
G	0016020	cellular_component	membrane
G	0055085	biological_process	transmembrane transport
H	0000086	biological_process	G2/M transition of mitotic cell cycle
H	0000922	cellular_component	spindle pole
H	0002027	biological_process	regulation of heart rate
H	0005246	molecular_function	calcium channel regulator activity
H	0005509	molecular_function	calcium ion binding
H	0005513	biological_process	detection of calcium ion
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005813	cellular_component	centrosome
H	0005819	cellular_component	spindle
H	0005829	cellular_component	cytosol
H	0005856	cellular_component	cytoskeleton
H	0005876	cellular_component	spindle microtubule
H	0005886	cellular_component	plasma membrane
H	0005929	cellular_component	cilium
H	0007186	biological_process	G protein-coupled receptor signaling pathway
H	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
H	0008076	cellular_component	voltage-gated potassium channel complex
H	0010856	molecular_function	adenylate cyclase activator activity
H	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
H	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
H	0016020	cellular_component	membrane
H	0016240	biological_process	autophagosome membrane docking
H	0019855	molecular_function	calcium channel inhibitor activity
H	0019901	molecular_function	protein kinase binding
H	0021762	biological_process	substantia nigra development
H	0030017	cellular_component	sarcomere
H	0030672	cellular_component	synaptic vesicle membrane
H	0031432	molecular_function	titin binding
H	0031514	cellular_component	motile cilium
H	0031982	cellular_component	vesicle
H	0032465	biological_process	regulation of cytokinesis
H	0032991	cellular_component	protein-containing complex
H	0034704	cellular_component	calcium channel complex
H	0035458	biological_process	cellular response to interferon-beta
H	0042995	cellular_component	cell projection
H	0043209	cellular_component	myelin sheath
H	0043539	molecular_function	protein serine/threonine kinase activator activity
H	0044305	cellular_component	calyx of Held
H	0044325	molecular_function	transmembrane transporter binding
H	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
H	0046872	molecular_function	metal ion binding
H	0048306	molecular_function	calcium-dependent protein binding
H	0050848	biological_process	regulation of calcium-mediated signaling
H	0051592	biological_process	response to calcium ion
H	0055117	biological_process	regulation of cardiac muscle contraction
H	0060291	biological_process	long-term synaptic potentiation
H	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
H	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
H	0071346	biological_process	cellular response to type II interferon
H	0072542	molecular_function	protein phosphatase activator activity
H	0097225	cellular_component	sperm midpiece
H	0097720	biological_process	calcineurin-mediated signaling
H	0098901	biological_process	regulation of cardiac muscle cell action potential
H	0099523	cellular_component	presynaptic cytosol
H	0140056	biological_process	organelle localization by membrane tethering
H	0140238	biological_process	presynaptic endocytosis
H	0141110	molecular_function	transporter inhibitor activity
H	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
H	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
H	1902494	cellular_component	catalytic complex
H	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
H	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering
I	0005216	molecular_function	monoatomic ion channel activity
I	0005249	molecular_function	voltage-gated potassium channel activity
I	0006811	biological_process	monoatomic ion transport
I	0006813	biological_process	potassium ion transport
I	0016020	cellular_component	membrane
I	0055085	biological_process	transmembrane transport
J	0000086	biological_process	G2/M transition of mitotic cell cycle
J	0000922	cellular_component	spindle pole
J	0002027	biological_process	regulation of heart rate
J	0005246	molecular_function	calcium channel regulator activity
J	0005509	molecular_function	calcium ion binding
J	0005513	biological_process	detection of calcium ion
J	0005515	molecular_function	protein binding
J	0005576	cellular_component	extracellular region
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005813	cellular_component	centrosome
J	0005819	cellular_component	spindle
J	0005829	cellular_component	cytosol
J	0005856	cellular_component	cytoskeleton
J	0005876	cellular_component	spindle microtubule
J	0005886	cellular_component	plasma membrane
J	0005929	cellular_component	cilium
J	0007186	biological_process	G protein-coupled receptor signaling pathway
J	0007259	biological_process	cell surface receptor signaling pathway via JAK-STAT
J	0008076	cellular_component	voltage-gated potassium channel complex
J	0010856	molecular_function	adenylate cyclase activator activity
J	0010880	biological_process	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
J	0010881	biological_process	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
J	0016020	cellular_component	membrane
J	0016240	biological_process	autophagosome membrane docking
J	0019855	molecular_function	calcium channel inhibitor activity
J	0019901	molecular_function	protein kinase binding
J	0021762	biological_process	substantia nigra development
J	0030017	cellular_component	sarcomere
J	0030672	cellular_component	synaptic vesicle membrane
J	0031432	molecular_function	titin binding
J	0031514	cellular_component	motile cilium
J	0031982	cellular_component	vesicle
J	0032465	biological_process	regulation of cytokinesis
J	0032991	cellular_component	protein-containing complex
J	0034704	cellular_component	calcium channel complex
J	0035458	biological_process	cellular response to interferon-beta
J	0042995	cellular_component	cell projection
J	0043209	cellular_component	myelin sheath
J	0043539	molecular_function	protein serine/threonine kinase activator activity
J	0044305	cellular_component	calyx of Held
J	0044325	molecular_function	transmembrane transporter binding
J	0046427	biological_process	positive regulation of receptor signaling pathway via JAK-STAT
J	0046872	molecular_function	metal ion binding
J	0048306	molecular_function	calcium-dependent protein binding
J	0050848	biological_process	regulation of calcium-mediated signaling
J	0051592	biological_process	response to calcium ion
J	0055117	biological_process	regulation of cardiac muscle contraction
J	0060291	biological_process	long-term synaptic potentiation
J	0060314	biological_process	regulation of ryanodine-sensitive calcium-release channel activity
J	0060315	biological_process	negative regulation of ryanodine-sensitive calcium-release channel activity
J	0071346	biological_process	cellular response to type II interferon
J	0072542	molecular_function	protein phosphatase activator activity
J	0097225	cellular_component	sperm midpiece
J	0097720	biological_process	calcineurin-mediated signaling
J	0098901	biological_process	regulation of cardiac muscle cell action potential
J	0099523	cellular_component	presynaptic cytosol
J	0140056	biological_process	organelle localization by membrane tethering
J	0140238	biological_process	presynaptic endocytosis
J	0141110	molecular_function	transporter inhibitor activity
J	1901842	biological_process	negative regulation of high voltage-gated calcium channel activity
J	1901844	biological_process	regulation of cell communication by electrical coupling involved in cardiac conduction
J	1902494	cellular_component	catalytic complex
J	1905913	biological_process	negative regulation of calcium ion export across plasma membrane
J	1990456	biological_process	mitochondrion-endoplasmic reticulum membrane tethering

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL

Chain	Residue	Details
E	ASP21-LEU33
E	ASP57-PHE69
E	ASP94-LEU106
E	ASP130-PHE142

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	88
Details	Transmembrane: {"description":"Helical; Name=Segment S1","evidences":[{"source":"PubMed","id":"32884139","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CR3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	112
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	84
Details	Transmembrane: {"description":"Helical; Name=Segment S2","evidences":[{"source":"PubMed","id":"32884139","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CR3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	112
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	76
Details	Transmembrane: {"description":"Helical; Name=Segment S3","evidences":[{"source":"PubMed","id":"32884139","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CR3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	72
Details	Transmembrane: {"description":"Helical; Voltage-sensor; Name=Segment S4","evidences":[{"source":"PubMed","id":"32884139","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CR3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	100
Details	Transmembrane: {"description":"Helical; Name=Segment S5","evidences":[{"source":"PubMed","id":"32884139","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CR3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	48
Details	Intramembrane: {"description":"Pore-forming; Name=Segment H5","evidences":[{"source":"PubMed","id":"32884139","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CR3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	104
Details	Transmembrane: {"description":"Helical; Name=Segment S6","evidences":[{"source":"PubMed","id":"32884139","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CR3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	404
Details	Region: {"description":"Mediates interaction with SLC5A3/SMIT1","evidences":[{"source":"UniProtKB","id":"O88943","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	20
Details	Motif: {"description":"Selectivity filter","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"37857637","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8J01","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8W4U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"37857637","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8W4U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"16319223","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	140
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	140
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	140
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1474585","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25441029","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27564677","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4UMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4V0C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5J03","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1474585","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27564677","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29724949","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5J03","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6CNN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6CNO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"1474585","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27564677","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5J03","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine; by CaMK4","evidences":[{"source":"UniProtKB","id":"P0DP29","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	4
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"24129315","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"UniProtKB","id":"P62157","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---