Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8IUJ

Cryo-EM structure of Euglena gracilis super-complex III2+IV2, composite

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
4a	0004129	molecular_function	cytochrome-c oxidase activity
4a	0009055	molecular_function	electron transfer activity
4a	0016020	cellular_component	membrane
4a	0019646	biological_process	aerobic electron transport chain
4a	0022904	biological_process	respiratory electron transport chain
4A	0004129	molecular_function	cytochrome-c oxidase activity
4A	0009055	molecular_function	electron transfer activity
4A	0016020	cellular_component	membrane
4A	0019646	biological_process	aerobic electron transport chain
4A	0022904	biological_process	respiratory electron transport chain
c1	0004129	molecular_function	cytochrome-c oxidase activity
c1	0005743	cellular_component	mitochondrial inner membrane
c1	0006119	biological_process	oxidative phosphorylation
c1	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
c1	0009060	biological_process	aerobic respiration
c1	0015990	biological_process	electron transport coupled proton transport
c1	0016020	cellular_component	membrane
c1	0016491	molecular_function	oxidoreductase activity
c1	0020037	molecular_function	heme binding
c1	0022904	biological_process	respiratory electron transport chain
c1	0046872	molecular_function	metal ion binding
C1	0004129	molecular_function	cytochrome-c oxidase activity
C1	0005743	cellular_component	mitochondrial inner membrane
C1	0006119	biological_process	oxidative phosphorylation
C1	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
C1	0009060	biological_process	aerobic respiration
C1	0015990	biological_process	electron transport coupled proton transport
C1	0016020	cellular_component	membrane
C1	0016491	molecular_function	oxidoreductase activity
C1	0020037	molecular_function	heme binding
C1	0022904	biological_process	respiratory electron transport chain
C1	0046872	molecular_function	metal ion binding
c2	0004129	molecular_function	cytochrome-c oxidase activity
c2	0005507	molecular_function	copper ion binding
c2	0005743	cellular_component	mitochondrial inner membrane
c2	0016020	cellular_component	membrane
c2	0022900	biological_process	electron transport chain
c2	0022904	biological_process	respiratory electron transport chain
c2	0042773	biological_process	ATP synthesis coupled electron transport
c2	0046872	molecular_function	metal ion binding
c2	1902600	biological_process	proton transmembrane transport
C2	0004129	molecular_function	cytochrome-c oxidase activity
C2	0005507	molecular_function	copper ion binding
C2	0005743	cellular_component	mitochondrial inner membrane
C2	0016020	cellular_component	membrane
C2	0022900	biological_process	electron transport chain
C2	0022904	biological_process	respiratory electron transport chain
C2	0042773	biological_process	ATP synthesis coupled electron transport
C2	0046872	molecular_function	metal ion binding
C2	1902600	biological_process	proton transmembrane transport
c3	0009055	molecular_function	electron transfer activity
c3	0016020	cellular_component	membrane
C3	0009055	molecular_function	electron transfer activity
C3	0016020	cellular_component	membrane
Qa	0004222	molecular_function	metalloendopeptidase activity
Qa	0006508	biological_process	proteolysis
Qa	0046872	molecular_function	metal ion binding
QA	0004222	molecular_function	metalloendopeptidase activity
QA	0006508	biological_process	proteolysis
QA	0046872	molecular_function	metal ion binding
Qb	0005739	cellular_component	mitochondrion
Qb	0005743	cellular_component	mitochondrial inner membrane
Qb	0022904	biological_process	respiratory electron transport chain
Qb	0046872	molecular_function	metal ion binding
QB	0005739	cellular_component	mitochondrion
QB	0005743	cellular_component	mitochondrial inner membrane
QB	0022904	biological_process	respiratory electron transport chain
QB	0046872	molecular_function	metal ion binding
Qc	0005743	cellular_component	mitochondrial inner membrane
Qc	0009055	molecular_function	electron transfer activity
Qc	0016020	cellular_component	membrane
Qc	0016491	molecular_function	oxidoreductase activity
Qc	0022904	biological_process	respiratory electron transport chain
Qc	0046872	molecular_function	metal ion binding
QC	0005743	cellular_component	mitochondrial inner membrane
QC	0009055	molecular_function	electron transfer activity
QC	0016020	cellular_component	membrane
QC	0016491	molecular_function	oxidoreductase activity
QC	0022904	biological_process	respiratory electron transport chain
QC	0046872	molecular_function	metal ion binding
Qd	0005743	cellular_component	mitochondrial inner membrane
Qd	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Qd	0008121	molecular_function	quinol-cytochrome-c reductase activity
Qd	0009055	molecular_function	electron transfer activity
Qd	0016020	cellular_component	membrane
Qd	0020037	molecular_function	heme binding
Qd	0022904	biological_process	respiratory electron transport chain
Qd	0046872	molecular_function	metal ion binding
Qd	1902600	biological_process	proton transmembrane transport
QD	0005743	cellular_component	mitochondrial inner membrane
QD	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
QD	0008121	molecular_function	quinol-cytochrome-c reductase activity
QD	0009055	molecular_function	electron transfer activity
QD	0016020	cellular_component	membrane
QD	0020037	molecular_function	heme binding
QD	0022904	biological_process	respiratory electron transport chain
QD	0046872	molecular_function	metal ion binding
QD	1902600	biological_process	proton transmembrane transport
Qe	0008121	molecular_function	quinol-cytochrome-c reductase activity
Qe	0016020	cellular_component	membrane
Qe	0051537	molecular_function	2 iron, 2 sulfur cluster binding
QE	0008121	molecular_function	quinol-cytochrome-c reductase activity
QE	0016020	cellular_component	membrane
QE	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Qg	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Qg	0045275	cellular_component	respiratory chain complex III
QG	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
QG	0045275	cellular_component	respiratory chain complex III
Qk	0005743	cellular_component	mitochondrial inner membrane
Qk	0022904	biological_process	respiratory electron transport chain
QK	0005743	cellular_component	mitochondrial inner membrane
QK	0022904	biological_process	respiratory electron transport chain

Functional Information from PROSITE/UniProt

site_id	PS00077
Number of Residues	55
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyviilpvfgltsliltsiihkdifgregmmyciisigvvgyfvwa..HH

Chain	Residue	Details
C1	TRP246-HIS300

site_id	PS00078
Number of Residues	49
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. ViHsfalptlgikvdaipgrinnisingltqglyvgy......CselCgsgHafM

Chain	Residue	Details
C2	VAL141-MET189

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsrweteknnGvAHFLEHMnFkGT

Chain	Residue	Details
QA	GLY57-THR80

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	78
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	378
Details	Domain: {"description":"Cytochrome c"}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"2558110","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P07143","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)